CAS 1510820-22-0

3-Dehydroxy ezetimibe open ring impurity

CAS: 1510820-22-0

3-Dehydroxy ezetimibe open ring impurity is an analog of the cholesterol-lowering drug ezetimibe. This compound has been shown to have potent anticancer activity by inhibiting cyclin-dependent kinases (CDKs), which are enzymes that regulate cell division. It induces apoptosis in human cancer cells and has been identified as a potential tumor protein kinase inhibitor. 3-Dehydroxy ezetimibe open ring impurity also exhibits kinase inhibitory activity against Chinese hamster ovary cells, indicating its potential for use as an anticancer agent. This compound can be found in urine samples of patients taking ezetimibe and may serve as a useful biomarker for monitoring treatment efficacy.

Fórmula: C₂₄H₂₁F₂NO₂

Pureza: Min. 95%

Peso molecular: 393.4 g/mol

Ref: 3D-KKC82022