CAS 152-62-5

Didrogesterona

Descripción:

Didrogesterona, con el número CAS 152-62-5, es un progestágeno sintético, que es un tipo de hormona que imita los efectos de la progesterona, una hormona natural involucrada en el ciclo menstrual y el embarazo. Se caracteriza por su capacidad para regular varios procesos reproductivos, lo que lo hace útil en el tratamiento de condiciones como la amenorrea, la endometriosis y ciertos tipos de infertilidad. Didrogesterona se administra típicamente por vía oral y es conocido por su favorable perfil de seguridad, ya que no presenta actividad androgénica o estrogénica significativa. La sustancia se absorbe generalmente bien en el tracto gastrointestinal y tiene una vida media relativamente corta, lo que requiere dosis regulares. Su estructura química presenta un esqueleto esteroide, que es común entre los progestágenos, y a menudo se formula en varias preparaciones farmacéuticas. Debido a su acción específica sobre los receptores de progesterona, Didrogesterona desempeña un papel crucial en la terapia de reemplazo hormonal y en el manejo de varios trastornos ginecológicos.

Fórmula: C₂₁H₂₈O₂

InChI: InChI=1/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20?,21+/m0/s1

Clave InChI: InChIKey=JGMOKGBVKVMRFX-HQZYFCCVSA-N

SMILES: C[C@]12[C@]3([C@]([C@]4([C@](C)(CC3)[C@@H](C(C)=O)CC4)[H])(C=CC1=CC(=O)CC2)[H])[H]

Sinónimos:

• (9Beta,10Xi)-Pregna-4,6-Diene-3,20-Dione
• (9b,10a)-Pregna-4,6-diene-3,20-dione
• (9beta,10alpha)-Pregna-4,6-diene-3,20-dione
• .DELTA.6-Retroprogesterone
• 10a-Isopregnenone
• 6-Dehydro-9.beta.,10.alpha.-progesterone
• 6-Dehydro-9b,10a-progesterone
• 6-Dehydroretroprogesterone
• 6α-Dehydro-retro-Δ4-pregnene-3,20-dione
• 6α-Dehydro-retro-Δ⁴-pregnene-3,20-dione
• 9beta,10alpha-Pregna-4,6-diene-3,20-dione (8CI)
• D6-Retroprogesterone
• Didrogesterona
• Diphaston
• Dufaston
• Duphaston
• Duvaron
• Dydrogesteron
• Gestatron
• Gynorest
• Hydrogesterone
• Isopregnenone
• Nsc 92336
• Pregna-4,6-diene-3,20-dione, (9β,10α)-
• Prodel
• Retro-6-dehydroprogesterone
• Retrone
• Retroprogesterone, 6-dehydro-
• Terolut
• Δ⁶-Retroprogesterone
• dyhdrogesterone
• 6-dehydro-9beta,10alpha-progesterone
• 10alpha-isopregnenone
• delta(sup6)-retroprogesterone
• 20-dione,(9beta,10alpha)-pregna-6-diene-3
• 17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
• 6-dehydro-retro-progesterone
• 20-dione,(9-beta,10-alpha)-pregna-6-diene-3
• 6-dehydro-retroprogesteron
• 10α-pregna-4,6-diene-3,20-dione

Dydrogesterone

CAS: 152-62-5

Forma y color: Neat

Ref: 61-FOR0328.00

DYDROGESTERONE CRS

CAS: 152-62-5

DYDROGESTERONE CRS

Ref: 41-Y0001004

Dydrogesterone

CAS: 152-62-5

Estrogens and progestins

Fórmula: C₂₁H₂₈O₂

Forma y color: White Off-White Solid

Peso molecular: 312.20893

Ref: 45-1231003

Dydrogesterone

CAS: 152-62-5

Fórmula: C₂₁H₂₈O₂

Forma y color: White To Off-White Solid

Peso molecular: 312.45

Ref: 4Z-D-123001

Dydrogesterone-d6

CAS: 152-62-5

Fórmula: C₂₁H₂₂D₆O₂

Peso molecular: 318.49

Ref: 4Z-D-123005

Dydrogesterone

CAS: 152-62-5

Dydrogesterone

Pureza: ≥98%

Peso molecular: 312.45g/mol

Ref: 54-BUP12472

Dydrogesterone

CAS: 152-62-5

Fórmula: C₂₁H₂₈O₂

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 312.45

Ref: 3B-D6262

Dydrogesterone

CAS: 152-62-5

Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies.

Fórmula: C₂₁H₂₈O₂

Pureza: 99.78% - 99.87%

Forma y color: Crystals From Acetone + Hexane Solid

Peso molecular: 312.45

Ref: TM-T3036

Dydrogesterone-d6 (Major)

Producto controlado

CAS: 152-62-5

Applications Labelled Dydrogesterone. A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.
References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),

Fórmula: C₂₁H₂₂D₆O₂

Forma y color: Neat

Peso molecular: 318.48

Ref: TR-D826002

Dydrogesterone

Producto controlado

CAS: 152-62-5

Dydrogesterone is a progestin medication that is used to treat symptoms of endometriosis in women. It can be used alone or in combination with estradiol benzoate. Dydrogesterone is not active against bacteria. High-sensitivity C-reactive protein (hsCRP) levels are an indicator of inflammation and have been shown to be elevated in untreated women with endometriosis. Histological analysis of tissue from these patients has revealed increased levels of dydrogesterone. Dydrogesterone binds to the progesterone receptor, which regulates the expression of genes that play a role in cell proliferation and differentiation. This regulation is mediated by nuclear DNA, which is transcribed into messenger RNA and translated into protein by ribosomes. Coumarin derivatives inhibit the production of mRNA by binding to the enzyme RNA polymerase II, which catalyzes the transcription process. Studies have shown that coumarin derivatives can reduce

Fórmula: C₂₁H₂₈O₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 312.45 g/mol

Ref: 3D-FD22631

Dydrogesterone

Producto controlado

CAS: 152-62-5

Applications A synthetic progestin largely used in hormone therapy, on the central nervous system by studying two markers of the neuroendocrine function: the neurosteroid allopregnanolone and the opioid .beta.-endorphin. Progestogen.
References Bernardi, F., et al.: Eur. J. Endocrinol., 138, 316 (1998), Rupprecht, R., et al.: Steroids, 64, 83 (1999), Uzunova, V., et al.: Brain Res., 976, 1 (2003), Pluchino, N., et al.: J. Steroid Biochem. Mol. Biol., 102, 205 (2006),

Fórmula: C₂₁H₂₈O₂

Forma y color: Neat

Peso molecular: 312.45

Ref: TR-D826000

Dydrogesterone

CAS: 152-62-5

Dydrogesterone

Forma y color: White

Ref: 47-138