CAS 15220-11-8

Sulfato de 4-metilumbeliferona de potasio

Descripción:

Sulfato de 4-metilumbeliferona de potasio, con el número CAS 15220-11-8, es un compuesto químico que pertenece a la clase de derivados sulfonados de la umbeliferona, un cumarín natural. Este compuesto se caracteriza por su grupo sulfonato, que mejora su solubilidad en agua, haciéndolo útil en diversas aplicaciones bioquímicas. Típicamente exhibe propiedades de fluorescencia, que son valiosas en química analítica y ensayos biológicos, particularmente en la detección de enzimas como las sulfatases. La forma de sal potásica contribuye a su estabilidad y solubilidad en soluciones acuosas. Además, el sulfato de 4-metilumbeliferona se utiliza a menudo como sustrato en reacciones enzimáticas y como sonda fluorescente en estudios celulares. Sus características estructurales incluyen un grupo metilo en la posición 4 de la columna vertebral de la umbeliferona, lo que influye en su reactividad e interacción con sistemas biológicos. En general, este compuesto sirve como una herramienta importante en la investigación bioquímica, particularmente en estudios que involucran la actividad enzimática y las vías metabólicas.

Fórmula: C₁₀H₈O₆S·K

InChI: InChI=1S/C10H8O6S.K/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14;/h2-5H,1H3,(H,12,13,14);

Clave InChI: InChIKey=ACUFSQJGNBCODF-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC(OS(=O)(=O)O)=CC2)OC(=O)C1.[K]

Sinónimos:

• Potassium 4-methylumbelliferone sulfate
• 2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt (1:1)
• Potassium 4-methylumbelliferyl sulfate
• Coumarin, 7-hydroxy-4-methyl-, hydrogen sulfate potassium salt
• 2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt

4-Methylumbelliferyl sulfate potassium salt, 98%

CAS: 15220-11-8

Substrate for sulfatase

Fórmula: C₁₀H₇KO₆S

Pureza: 98%

Forma y color: White, Powder

Peso molecular: 294.32

Ref: 02-J66160

2H-1-BENZOPYRAN-2-ONE,4-METHYL-7-(SULFOOXY)-, POTASSIUM SALT

CAS: 15220-11-8

Fórmula: C₁₀H₇KO₆S

Pureza: 97%

Forma y color: Solid

Peso molecular: 294.3223

Ref: IN-DA00HXY4

4-Methylumbelliferyl sulfate potassium salt

CAS: 15220-11-8

Fórmula: C₁₀H₇KO₆S

Pureza: (HPLC) ≥ 98%

Forma y color: White powder or solid

Peso molecular: 294.30

Ref: 7W-GC5001

4-Methylumbelliferyl sulphate potassium salt

CAS: 15220-11-8

4-Methylumbelliferyl sulphate potassium salt

Pureza: By hplc: >99% (Typical Value in Batch COA)

Forma y color: white solid

Peso molecular: 294.32g/mol

Ref: 54-BIB6119

4-Methylumbelliferyl Sulfate Potassium Salt

CAS: 15220-11-8

Applications Met-enkephalin analog found in opioid extracts of brain and adrenal chromaffin cells that is an artifact generated by trichloroacetic acid extraction. MUS is used as a fluorimetric substrate for arylsulphatase enzyme. Subsitution of the hydroxyl group of 4-methylumbelliferone (4-methyl-7-hydroxy-coumarin) causes the excitation wavelength of the umbelliferone to shift to shorter values and also brings about a decrease in fluorescence.Fluorescence: max. Abs = 334 mm; max. Em. = 370 mm
References Harinath, B., et al.: J. Neurochem., 18, 245 (1971), Marniemi, J., et al.: Int. J. Biochem., 4, 95 (1973), Bojarova, P., et al.: ChemBioChem., 9, 613 (2008),

Fórmula: C₁₀H₇O₆S·K

Forma y color: Neat

Peso molecular: 294.32

Ref: TR-M333100

4-Methylumbelliferyl sulfate, potassium salt

CAS: 15220-11-8

4-Methylumbelliferyl sulfate, potassium salt is a metabolite of 4-methylumbelliferone and has been used as a human serum marker. This molecule is conjugated with glucuronide and p-hydroxybenzoic acid to form the sulfate, glucuronide conjugate. The reaction mechanism of this compound is not known, but it is thought that the metabolism may involve oxidation at the methyl group. The analytical method for this compound can be performed using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). This method can also be used in vitro to test antimicrobial activity against bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa.

Fórmula: C₁₀H₇KO₆S

Pureza: Min. 99.0 Area-%

Peso molecular: 294.33 g/mol

Ref: 3D-M-6200

4-Methylumbelliferyl sulfate potassium salt

CAS: 15220-11-8

4-Methylumbelliferyl sulfate potassium salt serves as a superior fluorogenic substrate in enzyme detection assays. Upon enzymatic hydrolysis, it releases a highly fluorescent 4-methylumbelliferone moiety, enabling real-time analysis and quantification of enzyme activities. This product is ideal for a variety of biological assay applications, including in vitro diagnostics, drug discovery, and research purposes. Its excellent sensitivity, specificity, and performance ensure accurate and consistent results every time.

Fórmula: C₁₀H₇KO₆S

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 294.32 g/mol

Ref: 3D-EM15697

4-Methylumbelliferyl sulfate potassium salt

CAS: 15220-11-8

M04140 - 4-Methylumbelliferyl sulfate potassium salt

Fórmula: C₁₀H₇KO₆S

Pureza: 97%

Forma y color: Solid

Peso molecular: 294.32

Ref: 10-M04140

4-Methylumbelliferyl Sulfate Potassium Salt extrapure, 99%

CAS: 15220-11-8

Fórmula: C₁₀H₇KO₆S

Pureza: min. 99%

Forma y color: White, Powder

Peso molecular: 294.30

Ref: SR-21400