CAS 154-93-8

carmustina

Descripción:

carmustina, con el número CAS 154-93-8, es un potente agente alquilante utilizado principalmente en la quimioterapia del cáncer. Pertenece a la clase de las nitrosoureas, que se caracterizan por su capacidad para cruzar la barrera hematoencefálica, lo que las hace efectivas para tratar tumores cerebrales y ciertas otras malignidades. carmustina es un polvo cristalino blanco a blanco sucio que es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua. Su mecanismo de acción implica la formación de enlaces cruzados en el ADN, lo que inhibe la replicación y transcripción del ADN, llevando finalmente a la muerte celular. carmustina se administra típicamente por vía intravenosa y puede estar asociado con varios efectos secundarios, incluyendo mielosupresión, náuseas y efectos potenciales a largo plazo como toxicidad pulmonar. Debido a su reactividad y potencial para causar malignidades secundarias, es esencial un manejo y monitoreo cuidadosos durante su uso. En general, carmustina sigue siendo un componente crítico en los regímenes de tratamiento para ciertos cánceres, particularmente en casos donde otras terapias pueden ser menos efectivas.

Fórmula: C₅H₉Cl₂N₃O₂

InChI: InChI=1/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

Clave InChI: InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N

SMILES: N(C(NCCCl)=O)(CCCl)N=O

Sinónimos:

• 1,3-Bis(2-Chloroethyl)-1-Nitroso-Urea
• 1,3-Bis(2-chlorethyl)-1-nitrosourea
• 1,3-Bis(2-chloroethyl)-1-nitrosourea
• 1,3-Bis(2-chloroethyl)nitrosourea
• 1,3-Bis(β-chloroethyl)-1-nitrosourea
• Bcnu
• Becenum
• Becenun
• BiCNU
• Carmubris
• Carmustin
• Carmustina
• Dti 015
• Fda 0345
• Gliadel
• Gliadel Wafer
• N,N'-Bis(2-chloroethyl)-N-nitrosourea
• Nitrumon
• Nsc 409962
• Sk 27702
• Sri 1720
• Urea, 1,3-bis(2-chloroethyl)-1-nitroso-
• Urea, N,N'-bis(2-chloroethyl)-N'-nitroso-
• 1,3-bis(beta-chloroethyl)-1-nitrosourea
• n,n’-bis(2-chloroethyl)-n-nitroso-ure
• nci-c04773
• bischlorethylnitrosurea
• bis(2-chloroethyl)nitrosourea
• sk27702
• bischloroethylnitrosourea
• 1,3-bis(2-chloroethyl)-1-nitroso-ure
• fda0345

Carmustine

CAS: 154-93-8

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 214.05

Ref: 3B-C2634

CARMUSTINE CRS

CAS: 154-93-8

CARMUSTINE CRS

Forma y color: Powder

Ref: 41-Y0002128

Carmustine

CAS: 154-93-8

Compounds with other nitrogen function, nesoi

Fórmula: C₅H₉Cl₂N₃O₂

Forma y color: Light Yellow Powder

Peso molecular: 213.00718

Ref: 45-1096724

1,3-Bis(2-chloroethyl)nitrosourea

CAS: 154-93-8

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 214.0499

Ref: IN-DA003DHD

Carmustine

CAS: 154-93-8

Fórmula: C₅H₉Cl₂N₃O₂

Peso molecular: 214.05

Ref: 4Z-C-474001

Carmustine

CAS: 154-93-8

Carmustine

Pureza: ≥98%

Peso molecular: 214.05g/mol

Ref: 54-BUP13658

Carmustine

CAS: 154-93-8

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: ≥ 95.0%

Forma y color: Pale yellow to yellow-orange powder, amorphous solid or oily liquid

Peso molecular: 214.05

Ref: 7W-GP1721

Carmustine

CAS: 154-93-8

Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: 98% - 99.91%

Forma y color: Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)

Peso molecular: 214.05

Ref: TM-T3091

Carmustine

Producto controlado

CAS: 154-93-8

Stability Temperature Sensitive
Applications An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),

Fórmula: C₅H₉Cl₂N₃O₂

Forma y color: Light Yellow To Light Orange Colour

Peso molecular: 214.05

Ref: TR-C183875

Carmustine

CAS: 154-93-8

Carmustine is a DNA alkylating agent which also cross-links DNA. As a result Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, mean it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: Min. 85%

Forma y color: Powder

Peso molecular: 214.05 g/mol

Ref: 3D-FC19817

Carmustine - Bio-X ™

CAS: 154-93-8

Carmustine is a DNA alkylating agent which also cross-links DNA. As a result, Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, means it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.

Fórmula: C₅H₉Cl₂N₃O₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 214.05 g/mol

Ref: 3D-BC164289

1,3-BIS(2-CHLOROETHYL)NITROSOUREA

CAS: 154-93-8

Pureza: 97%

Peso molecular: 214.0500031

Ref: 10-F828460

1,3-Bis(2-chloroethyl-d4)-1-nitrosourea

Producto controlado

CAS: 154-93-8

Applications 1,3-Bis(2-chloroethyl-d4)-1-nitrosourea is a useful isotopically labeled compound of Carmustine (C183875)

Fórmula: C₅D₈HCl₂N₃O₂

Forma y color: Neat

Peso molecular: 222.09

Ref: TR-C183877