CAS 154445-77-9

N5-[[[(2,3-Dihidro-2,2,4,6,7-pentametil-5-benzofurano)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetoxi)carbonil]-L-ornitina

Descripción:

La sustancia química conocida como N5-[[[(2,3-Dihidro-2,2,4,6,7-pentametil-5-benzofurano)sulfonil]amino]iminometil]-N2-[(9H-fluoren-9-ilmetoxi)carbonil]-L-ornitina, con el número CAS 154445-77-9, es un compuesto orgánico complejo caracterizado por su intrincada estructura molecular. Presenta un grupo sulfonamida, conocido por su actividad biológica, particularmente en productos farmacéuticos. La presencia del moiety benzofurano contribuye a sus posibles interacciones con objetivos biológicos, mientras que el grupo fluorenilmetoxicarbonilo (Fmoc) se utiliza comúnmente en la síntesis de péptidos como un grupo protector. Se espera que el compuesto exhiba características específicas de solubilidad, estabilidad bajo ciertas condiciones y reactividad potencial debido a sus grupos funcionales. Su estructura sugiere aplicaciones potenciales en química medicinal, particularmente en el desarrollo de terapias dirigidas a vías biológicas específicas. Sin embargo, serían necesarios estudios detallados para elucidar completamente sus propiedades, incluyendo su farmacocinética, toxicidad y eficacia en sistemas biológicos.

Fórmula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m0/s1

Clave InChI: InChIKey=HNICLNKVURBTKV-NDEPHWFRSA-N

SMILES: C(OC(N[C@@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinónimos:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-5-[N′-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido]pentanoic acid
• (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]ornithine
• <span class="text-smallcaps">L</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-Arg(pbf)-OH
• FMOC-N-omega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
• Fmoc-<span class="text-smallcaps">L</span>-Arg(Pbf)
• Fmoc-L-Arg(Pbf)-OH
• N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N5-{N-[(2,2,4,5,7-pentamethyl-2,3-dihydro-1-benzofuran-6-yl)sulfonyl]carbamimidoyl}-D-ornithine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-ornithine
• Na-Fmoc-Nw-Pbf-L-arginine
• L-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 648.78

Ref: 3B-F0729

Nα-Fmoc-N^w-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-arginine, 98%

CAS: 154445-77-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 98%

Peso molecular: 648.78

Ref: 02-H59039

Fmoc-L-Arg(Pbf)-OH

CAS: 154445-77-9

M03398 - Fmoc-L-Arg(Pbf)-OH

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 96 %

Forma y color: Crystalline Powder

Peso molecular: 648.78

Ref: 10-M03398

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Pbf protection is especially recommended for multiple-Arg- and Trp-containinng peptides. TFA cleavage is best performed in the presence of a silane scavenger.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 99.4081%

Forma y color: White

Peso molecular: 648.78

Ref: 01-4089151

FMOC-Arg(Pbf)-OH

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: 98%

Forma y color: Solid

Peso molecular: 648.7690

Ref: IN-DA0039MD

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH

Pureza: 98%

Peso molecular: 648.77g/mol

Ref: 54-BI5913

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: ≥ 99.0%

Forma y color: White to almost white powder

Peso molecular: 648.77

Ref: 7W-GM9958

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

Fmoc-Arg(Pbf)-OH is an amido-resin that is used in the industrial preparation of polyamides and as a reactive component for the synthesis of various peptide or protein drugs. The polymerisation reaction leads to the formation of a linear chain with a high molecular weight and low viscosity. Fmoc-Arg(Pbf)-OH has been used as an envisaged component for the synthesis of acetylcholine, messenger RNA, and nicotinic acetylcholine receptor. Trifluoroacetic acid is commonly used as a solvent in this process.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: Min. 98.0 Area-%

Peso molecular: 648.77 g/mol

Ref: 3D-FLR-1746-PI

Fmoc-Arg(Pbf)-OH

CAS: 154445-77-9

The Fmoc-Arg(Pbf)-OH is a cyclic peptide that has been shown to have significant cytotoxicity against human tumor cells. It binds to integrin receptors, which are involved in transcriptional regulation and cellular proliferation. The Fmoc-Arg(Pbf)-OH has been shown to be hypoglycemic and it also possesses redox potential. The chemical biology of this compound is not yet known, but toxicity studies have shown that it is nontoxic in mice.

Fórmula: C₃₄H₄₀N₄O₇S

Pureza: Min. 98 Area-%

Forma y color: White Off-White Powder

Peso molecular: 648.77 g/mol

Ref: 3D-FF15787

Fmoc-Arg(Pbf)-OH

Producto controlado

CAS: 154445-77-9

Applications Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Fórmula: C₃₄H₄₀N₄O₇S

Forma y color: Neat

Peso molecular: 648.77

Ref: TR-F604100