CAS 1554458-53-5

Benzamide, N-cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-[(3,3,3-trifluoropropyl)amino]imidazo[1,2-b]pyridazin-3-yl]-2-methyl-

CAS: 1554458-53-5

Fórmula: C₂₇H₂₄F₅N₅O₃

Pureza: 98%

Peso molecular: 561.5032

Ref: IN-DA001NWW

BAY1217389

CAS: 1554458-53-5

BAY1217389

Pureza: ≥95%

Peso molecular: 561.5g/mol

Ref: 54-BUP12171

BAY1217389

CAS: 1554458-53-5

BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).

Fórmula: C₂₇H₂₄F₅N₅O₃

Pureza: 98.14% - 99.42%

Forma y color: Solid

Peso molecular: 561.5

Ref: TM-T3434

BAY 12-17389

CAS: 1554458-53-5

BAY 12-17389 is a novel anticancer drug that inhibits the activity of CDK4 and CDK6. It is an imidazopyrazine derivative, which binds to the ATP-binding pocket of the enzyme, thereby preventing its activation. BAY 12-17389 has shown anticancer activity in animal models for skin cancer and bladder cancer. In vitro assays have demonstrated that BAY 12-17389 is effective at inhibiting proliferation of cultured cells from different types of human cancers. The effective dose for BAY 12-17389 is not yet known but it has been shown to be safe at doses as high as 2 µM.

Fórmula: C₂₇H₂₄F₅N₅O₃

Pureza: Min. 95%

Peso molecular: 561.5 g/mol

Ref: 3D-EMC45853