CAS 15690-38-7

ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico

Descripción:

La sustancia química conocida como ácido (6R,7R)-7-amino-3-(hidroximetil)-8-oxo-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico, con el número CAS 15690-38-7, es un compuesto bicíclico que presenta una estructura de anillo de tiazolidina. Este compuesto se caracteriza por la presencia de un grupo amino, un grupo hidroximetilo y un grupo funcional ácido carboxílico, lo que contribuye a su potencial actividad biológica. La estereoquímica indicada por la configuración (6R,7R) sugiere disposiciones espaciales específicas de átomos que pueden influir en las interacciones del compuesto con objetivos biológicos. Su grupo oxo y el componente tiazolidina sugieren una reactividad potencial e interacciones con varios sistemas biológicos. Este compuesto es de interés en la química medicinal, particularmente en el desarrollo de antibióticos, debido a sus similitudes estructurales con agentes antibióticos conocidos. La estructura bicíclica única también puede conferir propiedades farmacológicas específicas, convirtiéndolo en un tema de investigación en el diseño y desarrollo de fármacos.

Fórmula: C₈H₁₀N₂O₄S

InChI: InChI=1S/C8H10N2O4S/c9-4-6(12)10-5(8(13)14)3(1-11)2-15-7(4)10/h4,7,11H,1-2,9H2,(H,13,14)/t4-,7-/m1/s1

Clave InChI: InChIKey=BQIMPGFMMOZASS-CLZZGJSISA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CO)[H]

Sinónimos:

• (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-Amino-3-hydroxymethylceph-3-em-4-carboxylic acid
• 3-Hydroxymethyl-7-aminoceph-3-em-4-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans)-
• 7-Amino-3-(Hydroxymethyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• 7-Amino-3-hydoxymethyl-3-cephem-carboxylic acid
• 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid
• 7-Amino-deacetylcephalosporanic acid
• 7β-Amino-3-(hydroxymethyl)-3-cephem-4-carboxylic acid
• Deacetyl-7-aminocephalosporanic acid

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Pureza: 95%

Forma y color: Solid

Peso molecular: 230.2410

Ref: IN-DA007HQ7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

CAS: 15690-38-7

(6R,7R)-7-Amino-3-Hydroxymethyl-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0.]Oct-2-Ene-2-Carboxylic Acid

Pureza: 98%

Peso molecular: 230.24g/mol

Ref: 54-OR1029784

Cefazedone Impurity 11

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Forma y color: Off-White Solid

Peso molecular: 230.24

Ref: 4Z-C-108012

Deacetyl-7-aminocephalosporanic acid

CAS: 15690-38-7

Deacetyl-7-aminocephalosporanic acid serves as a crucial intermediate in the production of β-lactam broad-spectrum cephalosporin antibiotics.

Fórmula: C₈H₁₀N₂O₄S

Pureza: 99.97%

Forma y color: Solid

Peso molecular: 230.24

Ref: TM-T21006

7-Aminodeacetylcephalosporanic Acid

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Pureza: >97.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 230.24

Ref: 3B-A2878

7-Amino-deacetylcephalosporanic Acid

Producto controlado

CAS: 15690-38-7

Applications Intermediate in the semi-synthetic cephalosporins synthesis. Found in Acremonium chrysogenum.
References Fukagawa, M. et al.; Agr. Biol. Chem. 55, 2163 (1991)

Fórmula: C₈H₁₀N₂O₄S

Forma y color: Neat

Peso molecular: 230.24

Ref: TR-A603420

(6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 15690-38-7

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 230.24000549316406

Ref: 10-F243053

Cefazedone Impurity 1

CAS: 15690-38-7

Fórmula: C₈H₁₀N₂O₄S

Peso molecular: 230.24

Ref: ST-EA-CP-C209001

7-Amino-3-(hydroxymethyl)-cephem-4-carboxylic acid

CAS: 15690-38-7

Cefepime is a broad-spectrum antibiotic that belongs to the group of β-lactam antibiotics. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit, which prevents bacterial protein synthesis. Cefepime hydrochloride is a prodrug that is hydrolyzed in vivo to cefepime, its active form. Cefepime hydrochloride has been shown to inhibit the production of subtilisin and acylase, enzymes involved in the digestion of proteins and fats. The hydrolysis reaction also increases the solubility of cefepime. The crystallization process for cefepime hydrochloride involves heating with organic solvents such as methanol and ethanol. This process can be used for purification and isolation from impurities.

Fórmula: C₈H₁₀N₂O₄S

Pureza: Min. 95%

Peso molecular: 230.24 g/mol

Ref: 3D-FA36388