CAS 158966-92-8

Montelukast

Descripción:

Montelukast es un antagonista del receptor de leucotrienos que se utiliza principalmente en el manejo del asma y la rinitis alérgica. Funciona inhibiendo la acción de los leucotrienos, que son mediadores inflamatorios que contribuyen a la broncoconstricción y la producción de moco. Montelukast se administra típicamente por vía oral y está disponible en varias formulaciones, incluyendo tabletas y formas masticables. La sustancia tiene una fórmula molecular de C35H36ClNNaO3S y un peso molecular de aproximadamente 608.2 g/mol. Se caracteriza por su alta solubilidad en agua y su estabilidad en condiciones normales de almacenamiento. Montelukast generalmente es bien tolerado, con efectos secundarios comunes que incluyen dolor de cabeza, trastornos gastrointestinales y, en casos raros, cambios de humor. Su farmacocinética indica que tiene una vida media relativamente larga, lo que permite una dosificación una vez al día. El compuesto se clasifica como un medicamento de prescripción y a menudo se utiliza como parte de un plan integral de manejo del asma, particularmente para pacientes que experimentan broncoconstricción inducida por el ejercicio o alergias estacionales.

Fórmula: C₃₅H₃₆ClNO₃S

InChI: InChI=1/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/t32-/m1/s1

Clave InChI: InChIKey=UCHDWCPVSPXUMX-TZIWLTJVSA-N

SMILES: C(S[C@H](CCC1=C(C(C)(C)O)C=CC=C1)C2=CC(/C=C/C3=NC4=C(C=C3)C=CC(Cl)=C4)=CC=C2)C5(CC(O)=O)CC5

Sinónimos:

• (1-{[(1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl)sulfanyl]methyl}cyclopropyl)acetic acid
• (2Beta,3Alpha,5Alpha,16Beta,17Beta)-3,17-Bis(Acetyloxy)-16-(1-Methylpiperidinium-1-Yl)-2-(Piperidin-1-Yl)Androstane Bromide
• (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid
• 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid
• 1-[[[(R)-1-[3-[(E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid
• 2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
• 2-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropyl]acetic acid
• Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-
• Cyclopropaneacetic acid, 1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-, [R-(E)]-
• Montelukas
• Velukast
• [1-[[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)vinyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid
• {1-[({(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid
• {1-[({(1R)-1-{3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid

Cyclopropaneacetic acid,1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-

CAS: 158966-92-8

Fórmula: C₃₅H₃₆ClNO₃S

Pureza: 99%

Forma y color: Solid

Peso molecular: 586.1832

Ref: IN-DA00AOF9

(R,E)-2-(1-(((1-(3-(2-(7-Chloroquinolin-2-Yl)Vinyl)Phenyl)-3-(2-(2-Hydroxypropan-2-Yl)Phenyl)Propyl)Thio)Methyl)Cyclopropyl)Acetic Acid

CAS: 158966-92-8

(R,E)-2-(1-(((1-(3-(2-(7-Chloroquinolin-2-Yl)Vinyl)Phenyl)-3-(2-(2-Hydroxypropan-2-Yl)Phenyl)Propyl)Thio)Methyl)Cyclopropyl)Acetic Acid

Pureza: 99%

Peso molecular: 586.18g/mol

Ref: 54-OR1025583

Montelukast

CAS: 158966-92-8

Montelukast

Pureza: ≥98%

Peso molecular: 586.18g/mol

Ref: 54-BUP14076

Montelukast Sodium

CAS: 151767-02-1, 158966-92-8

Fórmula: C₃₅H₃₅ClNNaO₃S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 608.17

Ref: 3B-M2340

Montelukast

CAS: 158966-92-8

Montelukast (Singular), oral asthma med, linked to rare liver injury.

Fórmula: C₃₅H₃₆ClNO₃S

Pureza: 98.56% - >99.99%

Forma y color: Solid

Peso molecular: 586.18

Ref: TM-T1677

Montelukast Impurity 32

CAS: 1093746-29-2, 158966-92-8

Fórmula: C₂₉H₂₆ClNO

Peso molecular: 439.98

Ref: 4Z-M-3059

Montelukast - Bio-X ™

CAS: 158966-92-8

Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
Montelukast is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₃₅H₃₆ClNO₃S

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 586.19 g/mol

Ref: 3D-BM164608

Montelukast

CAS: 158966-92-8

Leukotriene receptor antagonist

Fórmula: C₃₅H₃₆ClNO₃S

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 586.18 g/mol

Ref: 3D-FM137467

Montelukast-d6 Sodium Salt

Producto controlado

CAS: 1093746-29-2, 151767-02-1, 158966-92-8

Fórmula: C₃₅H₂₉D₆ClNNaO₃S

Forma y color: Neat

Peso molecular: 614.2

Ref: TR-M568002

2’-Des(1-hydroxy-1-methylethyl)-2’-carboxy Montelukast Bissodium Salt

Producto controlado

CAS: 158966-92-8

Applications 2’-Des(1-hydroxy-1-methylethyl)-2’-carboxy Montelukast Bissodium Salt is an impurity of Montelukast Sodium Salt (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic.
References Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998)

Fórmula: C₃₃H₂₈ClNNa₂O₄S

Forma y color: Neat

Peso molecular: 616.077

Ref: TR-D290480