CAS 16053-52-4

1-(2'-desoxi-beta-treopentofuranosil)timina

Descripción:

1-(2'-desoxi-beta-treopentofuranosil)timina, con el número CAS 16053-52-4, es un análogo de nucleósido que presenta una base de timina unida a un azúcar de desoxirribosa. Este compuesto se caracteriza por su configuración única de azúcar, específicamente la forma beta-treo, que lo distingue de otros nucleósidos. La presencia de la porción de desoxirribosa indica que es un componente del ADN, y la base de timina contribuye a su papel en la estructura y función de los ácidos nucleicos. Este compuesto es de interés en la investigación bioquímica y farmacéutica, particularmente en el estudio de las interacciones de los ácidos nucleicos y el desarrollo de agentes antivirales o anticancerígenos. Sus propiedades estructurales pueden influir en su actividad biológica, estabilidad e interacción con enzimas u otras biomoléculas. Además, la modificación del componente de azúcar puede afectar la capacidad del compuesto para imitar nucleósidos naturales, lo que podría impactar su incorporación en ácidos nucleicos y su eficacia general en aplicaciones terapéuticas.

Fórmula: C₁₀H₁₄N₂O₅

InChI: InChI=1/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7-,8-/m1/s1

SMILES: Cc1cn([C@H]2C[C@H]([C@@H](CO)O2)O)c(=O)nc1O

Sinónimos:

• 1-(2'-Deoxy-beta-D-threo-pentofuranosyl)thymine
• 1-Dpft
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-threo-pentofuranosyl)-5-methyl-
• 1-(2-deoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(2'-Deoxy-beta-threopentofuranosyl)thymine
• beta-T 1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil, Zidovudine impurity 6,Zidovudine impurity M
• Stavudine EP Impurity B (Zidovudine EP Impurity F)
• 1-(2'-DEOXY-SS-THREOPENTOFURANOSYL)THYMINE
• Zidovudine Impurity 6(Zidovudine EP Impurity F)
• Zidovudine EP Impurity F (Stavudine EP Impurity B)
• 1-(2-Deoxy--D-xylofuranosyl)-5-methyluracil
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-threo-pentofuranosyl)-5-methyl-
• Zidovudine EP Impurity F
• 1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil
• 1-(2'-Deoxy-β-D-threo-pentofuranosyl)thymine
• 1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil
• 1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil, 3’-FddT, Alovudine
• Stavudine EP Impurity B
• 3'-β-Thymidine
• Stavudine Impurit Ⅳ: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione( 3'-β-Thymidine)
• Zidovudine impurity M
• 1-(2-Deoxy-β-D-threopentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• Stavudine Impurit Ⅳ: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione( 3’-β-Thymidine)
• 1-((2R,4R,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione
• 3’-β-Thymidine
• Thymidine 3''-Epimer
• 1-((2S,4R,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Zidovudine Impurity F

CAS: 16053-52-4

Fórmula: C₁₀H₁₄N₂O₅

Forma y color: White To Off-White Solid

Peso molecular: 242.23

Ref: 4Z-Z-087

1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil

CAS: 16053-52-4

1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil is a Nucleoside Derivative - Xylo-nucleoside.

Fórmula: C₁₀H₁₄N₂O₅

Forma y color: Solid

Peso molecular: 242.23

Ref: TM-TNU0990

3’-β-Thymidine-d3

Producto controlado

CAS: 16053-52-4

Applications An intermediate in the production of labelled fluorothymidine derivatives
References Roberts, G., et al.: Biochem. Pharmacol., 46, 2209 (1993), Hatano, A., et al.: Bioorg. Med. Chem., 16, 3866 (2008),

Fórmula: C₁₀H₁₁D₃N₂O₅

Forma y color: Neat

Peso molecular: 245.25

Ref: TR-T412007

3’-β-Thymidine

Producto controlado

CAS: 16053-52-4

Impurity Stavudine EP Impurity B
Applications 3’-β-Thymidine (Stavudine EP Impurity B) is an intermediate in the production of fluorothymidine and phosphorylase derivatives (1,2). Stavudine is used as an antiviral agent. Reverse transcriptase inhibitor (3).
References 1. Roberta, G. et al.: Biochem. Pharmacol. 1993 Dec 14;46(12):2209-18.2. Hatano, A. et al.: Bioorg. Med. Chem. 2008 Apr 1;16(7):3866-703. Santiprabhob, J. et al.: Biomed. Res. Int. 2017;2017:7481597.

Fórmula: C₁₀H₁₄N₂O₅

Forma y color: Neat

Peso molecular: 242.229

Ref: TR-T412005

1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil

CAS: 16053-52-4

1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.

Fórmula: C₁₀H₁₄N₂O₅

Pureza: Min. 95%

Peso molecular: 242.23 g/mol

Ref: 3D-ID144724

Zidovudine EP Impurity F

CAS: 16053-52-4

Fórmula: C₁₀H₁₄N₂O₅

Peso molecular: 242.23

Ref: ST-EA-CP-Z6006