CAS 161796-78-7

Esomeprazol sódico

Descripción:

Esomeprazol sódico es un inhibidor de la bomba de protones (IBP) utilizado principalmente para tratar la enfermedad por reflujo gastroesofágico (ERGE) y otras condiciones asociadas con la producción excesiva de ácido estomacal. Es el S-enantiómero del omeprazol, lo que mejora su eficacia y biodisponibilidad. Este compuesto se presenta típicamente como una sal sódica, lo que mejora su solubilidad en soluciones acuosas. Esomeprazol sódico actúa inhibiendo de forma irreversible la enzima H+/K+ ATPasa en las células parietales gástricas, lo que lleva a una reducción significativa en la secreción de ácido gástrico. Se caracteriza por su forma de polvo cristalino blanco a blanco amarillento, con una fórmula molecular que incluye carbono, hidrógeno, nitrógeno, oxígeno y sodio. La sustancia es generalmente estable en condiciones normales, pero debe almacenarse alejada de la humedad y la luz para mantener su potencia. Comúnmente administrado en forma oral, Esomeprazol sódico se absorbe bien en el tracto gastrointestinal, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la administración. Su farmacocinética puede verse influenciada por factores como la ingesta de alimentos y las variaciones metabólicas individuales.

Fórmula: C₁₇H₁₉N₃O₃S·Na

InChI: InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1

Clave InChI: InChIKey=HVAJOLFRLWQQQL-JIDHJSLPSA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]

Sinónimos:

• (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• (S)-Omeprazole sodium
• 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt, (S)-
• 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
• 1H-benzimidazole, 5-Methoxy-2-[[(4-Methoxy-3,5-dimethyl-2-PYRIDINYL)methyl]sulfinyl]-, sodium salt
• 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
• Bis[5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)Methylsulfinyl]Benzimidazol-1-Yl]Magnesium
• Esomeprazole Na
• Esomeprazole sodium salt
• Esomeprazoleandsalts
• H 199/18 sodium
• Sodium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide
• sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-2,3-dihydrobenzimidazol-1-ide

Esomeprazole Sodium

CAS: 161796-78-7

Forma y color: Neat

Ref: 61-FOR3373.00

ESOMEPRAZOLE SODIUM CRS

CAS: 161796-78-7

ESOMEPRAZOLE SODIUM CRS

Forma y color: Added Added

Ref: 41-Y0002075

Esomeprazole Sodium

CAS: 161796-78-7

Compounds containing an unfused pyridine ring in the structure, nesoi

Fórmula: C₁₇H₁₈N₃NaO₃S

Forma y color: White Off-White Powder

Peso molecular: 367.09666

Ref: 45-1249790

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: %

Forma y color: Solid

Peso molecular: 367.3979

Ref: IN-DA001VVZ

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium

Pureza: ≥98%

Peso molecular: 367.4g/mol

Ref: 54-BUP10558

Esomeprazole sodium salt hydrate

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: (Titration) ≥ 98.0%

Forma y color: White to off-white or pale yellow crystalline powder

Peso molecular: 367.40

Ref: 7W-GP5980

Esomeprazole Sodium Salt

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃O₃S·Na

Forma y color: White To Off-White Solid

Peso molecular: 344.42 22.99

Ref: 4Z-O-029

Esomeprazole Sodium

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃O₃S·Na

Forma y color: Neat

Peso molecular: 367.40

Ref: 86-MM3373.00

(S)-Omeprazole Sodium Salt

CAS: 161796-78-7

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 367.40

Ref: 3B-O0560

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.

Fórmula: C₁₇H₁₈N₃O₃S·Na

Pureza: 98.17% - >99.99%

Forma y color: Solid

Peso molecular: 367.4

Ref: TM-T2686L

Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

CAS: 161796-78-7

Pureza: 95.0%

Peso molecular: 367.3999938964844

Ref: 10-F219014

Esomeprazole sodium

CAS: 161796-78-7

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: (%) Min. 95%

Forma y color: Powder

Peso molecular: 367.4 g/mol

Ref: 3D-IM58097

Esomeprazole sodium - EP

CAS: 161796-78-7

Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.

Fórmula: C₁₇H₁₈N₃NaO₃S

Pureza: Min. 95%

Forma y color: White/Off-White Solid

Peso molecular: 367.4 g/mol

Ref: 3D-IE177087

Esomeprazole Sodium

CAS: 161796-78-7

Fórmula: C₁₇H₁₉N₃O₃SNa

Peso molecular: 345.4 : 23.0

Ref: ST-EA-CP-E14021