CAS 161973-10-0

esomeprazol magnésico

Descripción:

esomeprazol magnésico es un inhibidor de la bomba de protones (IBP) utilizado principalmente para tratar la enfermedad por reflujo gastroesofágico (ERGE) y otras condiciones asociadas con la producción excesiva de ácido estomacal. Es la sal de magnesio del esomeprazol, que es el S-enantiómero del omeprazol. Este compuesto actúa inhibiendo de forma irreversible la enzima H+/K+ ATPasa en las células parietales gástricas, lo que lleva a una disminución en la secreción de ácido gástrico. esomeprazol magnésico se administra típicamente en forma oral y es conocido por su mejor biodisponibilidad en comparación con su contraparte racémica. La sustancia se caracteriza por su apariencia de polvo cristalino blanco a blanco sucio, y es soluble en agua y metanol, lo que la hace adecuada para diversas formulaciones farmacéuticas. Su farmacocinética implica una rápida absorción, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la administración. Los efectos secundarios comunes pueden incluir dolor de cabeza, náuseas y dolor abdominal, mientras que el uso a largo plazo se ha asociado con riesgos potenciales como deficiencia de vitamina B12 y mayor susceptibilidad a infecciones gastrointestinales.

Fórmula: (C₁₇H₁₈N₃O₃S)₂·Mg

InChI: InChI=1/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1

Clave InChI: InChIKey=KWORUUGOSLYAGD-UHFFFAOYSA-N

SMILES: C(S1=O[Mg+2]2([N]3=C(S(CC4=C(C)C(OC)=C(C)C=N4)=O2)[N-]C=5C3=CC=C(OC)C5)[N]6=C1[N-]C=7C6=CC=C(OC)C7)C8=C(C)C(OC)=C(C)C=N8

Sinónimos:

• (-)-Omeprazole magnesium
• (S)-Omeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]magnesium
• H 199/18
• Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
• Magnesium Bis(5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide)
• Magnesium, bis[5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]-, [T-4-(S),(S)]-
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN³]-, (T-4)-
• Nexium
• Perprazole
• Raciper
• magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide)
• Esomeprazole magnesium
• (T-4)-Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]magnesium
• Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, (T-4)-
• Esomeprazole magnesium Q: What is the CAS Number of
• Esomeprazole Magnesium(Random Configuration)
• Esomeprazole magnesium Esomeprazole magnesium(API)
• 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt
• ESOMEPRAZOLE MAGNESIUM/SODIUM
• Esomeprazole magnesiumQ: What is
• (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1)
• Esomeprazole magnesium Q: What is the storage condition of
• Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide]
• Esomeprazole magnesium Q: What are the applications of
• Esomeprazole magnesium USP/EP/BP
• Chebi:50309
• Esomeprazole magnesium (S-Omeprazole magnesium)
• NEXIUM(esomeprazolemagnesium)
• Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
• Esomeprazole magnesium API
• Esomeprazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt
• ESOMEPRAZOLE MAGNESIUM SAMPLE
• EsMeprazole Magne-siuM Trihydrate
• S-Form magnesium salt

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 713.1212

Ref: IN-DA001SKP

Esomeprazole Magnesium Salt

CAS: 161973-10-0

Fórmula: C₁₇H₁₈N₃O₃S·Mg

Forma y color: White To Off-White Solid

Peso molecular: 2*344.41 24.30

Ref: 4Z-O-0213

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium

Pureza: ≥98%

Peso molecular: 713.12g/mol

Ref: 54-BUP13843

Esomeprazole Magnesium(Random Configuration)

CAS: 161973-10-0

Esomeprazole Magnesium(Random Configuration)

Pureza: 99%

Peso molecular: 713.12g/mol

Ref: 54-IN11944

Esomeprazole Magnesium

CAS: 161973-10-0

Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Pureza: 98.76% - 99.73%

Forma y color: Solid

Peso molecular: 713.12

Ref: TM-T2686

Esomeprazole magnesium

CAS: 161973-10-0

Esomeprazole magnesium is a proton-pump inhibitor that is used to treat gastroesophageal reflux disease, Zollinger–Ellison syndrome, and other conditions. Esomeprazole magnesium binds to the H+/K+ ATPase enzyme in the stomach and inhibits acid production. It also decreases the release of histamine from cells in the stomach lining, thereby decreasing gastric acid secretion. This drug has been shown to be effective for treating Helicobacter pylori infections and reducing the risk of ulcers associated with nonsteroidal anti-inflammatory drugs in patients with hepatic impairment or those taking omeprazole. The efficacy of esomeprazole magnesium can be measured by its concentration-time curve, which can be determined through blood sampling.

Fórmula: (C₁₇H₁₈N₃O₃S)₂•Mg

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 713.12 g/mol

Ref: 3D-FE46488

Esomeprazole Magnesium

CAS: 161973-10-0

Fórmula: C₃₄H₃₆MgN₆O₆S₂

Peso molecular: 713.12

Ref: ST-EA-CP-E14022