CAS 16391-75-6

29-Nordammara-17(20),24-dieno-21-ácido oico, 16-(acetiloxi)-3,11-dihidroxi-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, comp. con 2,2′-iminobis[etanol] (1:1)

Descripción:

29-Nordammara-17(20),24-dien-21-ácido oico, 16-(acetyloxy)-3,11-dihidroxi-, es un compuesto orgánico complejo caracterizado por su estructura esteroidal única, que incluye múltiples grupos hidroxilo y un grupo funcional acetyloxy. Este compuesto presenta una estereoequilibrio específico, denotado por su configuración detallada, que influye en su actividad biológica e interacciones. La presencia de 2,2′-iminobis[etanol] indica que forma un complejo 1:1 con esta amina, lo que podría afectar su solubilidad y reactividad. Es probable que el compuesto exhiba diversas propiedades farmacológicas, dadas sus características estructurales, que pueden incluir efectos antiinflamatorios u otros efectos terapéuticos. Su número CAS, 16391-75-6, permite una identificación precisa en bases de datos químicas. En general, las características de esta sustancia sugieren que puede tener aplicaciones en química medicinal o farmacología, aunque las actividades biológicas específicas requerirían una investigación adicional a través de estudios empíricos.

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

InChI: InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

Clave InChI: InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H].N(CCO)CCO

Sinónimos:

• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid - 2,2'-iminodiethanol (1:1)
• (3alpha,8alpha,9beta,13alpha,14beta,16beta,17(Z))-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1)
• (4alpha,8alpha,9beta,13alpha,14beta,17Z)-16beta-Acetoxy-3alpha,11alpha-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compound with 2,2'-iminodiethanol (1:1)
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, compd. with 2,2′-iminodiethanol (1:1), (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)
• Diethanolamine fusidate
• Ethanol, 2,2′-iminobis-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oate (salt)

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate

Fórmula: C₃₁H₄₇NaO₆ / C₃₁H₄₈O₆

Pureza: 81.2% / 77.8%

Forma y color: White

Peso molecular: 538.32703 / 516.34509

Ref: 47-118

Diethanolamine Fusidate

CAS: 16391-75-6

Fórmula: C₃₅H₅₉NO₈

Forma y color: Solid

Peso molecular: 621.8449

Ref: IN-DA001UJN

Diethanolamine Fusidate

CAS: 16391-75-6

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Forma y color: White To Off-White Solid

Peso molecular: 516.72 105.14

Ref: 4Z-F-5418

Diethanolamine Fusidate

CAS: 16391-75-6

Forma y color: Neat

Ref: 86-MM3832.00

Diethanolamine Fusidate

CAS: 16391-75-6

Stability Hygroscopic
Applications A bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid (F865500). Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Findon, G. et al.: Lab. Anim. Sci., 41, 462 (1991); Parsons, R.L. et al.: Curr. Chemother. Proc. Int. Cong. Chemother., 10, 384 (1978);

Fórmula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Forma y color: Neat

Peso molecular: 621.84

Ref: TR-D441880

Diethanolamine Fusidate

CAS: 16391-75-6

Diethanolamine Fusidate: orally better-absorbed bacteriostatic antibiotic; inhibits protein synthesis in prokaryotes.

Fórmula: C₃₅H₅₉NO₈

Forma y color: Solid

Peso molecular: 621.86

Ref: TM-T70323

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate is an aminoglycoside antibiotic that inhibits protein synthesis in bacteria by binding to the ribosomes. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Diethanolamine fusidate has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Fórmula: C₃₅H₅₉NO₈

Pureza: 95%Min

Peso molecular: 621.84 g/mol

Ref: 3D-FD173301