CAS 168626-94-6
:Clorhidrato de conivaptán
Descripción:
Clorhidrato de conivaptán es un compuesto sintético clasificado como un antagonista dual de los receptores de vasopresina, que se dirige específicamente a los receptores V1A y V2. Se utiliza principalmente en el tratamiento de condiciones asociadas con hiponatremia, particularmente en pacientes con insuficiencia cardíaca o síndrome de secreción inadecuada de hormona antidiurética (SIADH). La sustancia se administra típicamente por vía intravenosa y es conocida por su capacidad para promover la aquaresis, que es la excreción de agua libre sin la pérdida de electrolitos. Clorhidrato de conivaptán se caracteriza por su relativamente baja solubilidad en agua, lo que puede influir en su formulación y métodos de entrega. El compuesto tiene una estructura molecular específica que contribuye a su actividad farmacológica, y se metaboliza principalmente en el hígado, con una vida media que permite regímenes de dosificación efectivos. Al igual que con cualquier medicamento, los efectos secundarios potenciales pueden incluir hipotensión, desequilibrios electrolíticos y reacciones en el sitio de infusión, lo que requiere un monitoreo cuidadoso durante el tratamiento.
Fórmula:C32H26N4O2·HCl
InChI:InChI=1/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
Clave InChI:InChIKey=BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C(C3=C(CC1)N=C(C)N3)=CC=CC2)C4=CC=C(NC(=O)C5=C(C=CC=C5)C6=CC=CC=C6)C=C4.Cl
Sinónimos:- Conivaptan Monohydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamidhydrochlorid
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride (1:1)
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazépin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide chlorhydrate
- Vaprisol
- Ym 087
- [1,1'-biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- [1,1′-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
- Conivaptan hydrochloride
- N-[4-[(4,5-Dihydro-2-MethyliMidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxaMide Hydrochloride
- N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochkoride
- Conivaptan Hydrochloride Q: What is the CAS Number of
- Conivaptan HCl
- Conivaptan HydrochlorideQ: What is
- Conivaptan HCI
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide hydrochloride
- Conivaptan hydrochloride [usan]
- Conivaptan Hydrochloride Q: What is the storage condition of
- Conivaptan Hydrochloride Q: What are the applications of
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamid
- Unii-75L57R6X36
- Conivaptan hydrochloride USP/EP/BP
- N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochloride, >=99%
- [1,1'-Biphenyl]-2-carboxamide,N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-,hydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-biphenyl]-2-carboxamide, hydrochloride (1:1)
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Encontrado 9 productos.
[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
CAS:Fórmula:C32H27ClN4O2Pureza:98%Forma y color:SolidPeso molecular:535.0354Conivaptan HCl
CAS:Fórmula:C32H26N4O2·HClForma y color:White To Off-White SolidPeso molecular:498.59 36.46Conivaptan Hydrochloride
CAS:Producto controladoFórmula:C32H26N4O2·ClHForma y color:NeatPeso molecular:535.04Conivaptan hydrochloride
CAS:<p>Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and</p>Fórmula:C32H26N4O2·HClPureza:98.33% - 99.86%Forma y color:SolidPeso molecular:535.04Conivaptan Hydrochloride
CAS:Producto controlado<p>Applications Used in treatment of congestive heart failure.<br>References Mao, Z., et al.: Clin. Ther., 31, 1542 (2009), Arai, Y., et al.: J. Pharm. Sci., 109, 53 (2009),<br></p>Fórmula:C32H26N4O2·ClHForma y color:NeatPeso molecular:535.04Conivaptan hydrochloride
CAS:Producto controlado<p>Conivaptan hydrochloride is a selective, orally active vasopressin receptor antagonist that has been shown to be effective in the treatment of congestive heart failure. Conivaptan hydrochloride is used in experimental models to study its efficacy and safety. The long-term efficacy of conivaptan hydrochloride was demonstrated in a chronic oral study with rats. Optimum concentrations for conivaptan hydrochloride are between 0.5 and 2 mg/kg body weight, which should be administered three times daily. In patients with hepatic impairment, the concentration–time curve of conivaptan hydrochloride may be affected so that higher doses are required to achieve the desired effect. This drug also interacts with drugs such as warfarin, beta blockers, or calcium channel blockers. Patients with high body mass index or systolic pressure should not use this medication because it can lead to serious side effects.</p>Fórmula:C32H27ClN4O2Pureza:Min. 95%Forma y color:White PowderPeso molecular:535.04 g/mol
![[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)car…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001Y6H.jpg&w=3840&q=75)
