CAS 17090-79-8

Monensina

Descripción:

Monensina es un antibiótico ionóforo de polietileno producido principalmente por la fermentación de la bacteria *Streptomyces cinnamonensis*. Se caracteriza por su capacidad para transportar iones de sodio a través de membranas lipídicas, lo que interrumpe el equilibrio iónico celular y afecta varios procesos biológicos. Monensina es un polvo cristalino blanco a blanco sucio que es soluble en disolventes orgánicos como el metanol y el etanol, pero tiene una solubilidad limitada en agua. Su fórmula molecular es C36H61NaO11, y tiene una estructura compleja que presenta múltiples anillos de éter cíclicos. Monensina se utiliza ampliamente en medicina veterinaria, particularmente en ganado, para mejorar la eficiencia alimentaria y prevenir la coccidiosis, una enfermedad parasitaria. Además, se ha estudiado por sus posibles aplicaciones en medicina humana, incluido el tratamiento del cáncer y como agente antiviral. Sin embargo, su uso debe ser gestionado cuidadosamente debido a la posible toxicidad y el desarrollo de resistencia en los organismos objetivo. En general, Monensina es un compuesto significativo tanto en contextos agrícolas como farmacéuticos.

Fórmula: C₃₆H₆₁NaO₁₁

InChI: InChI=1/C37H64O10.Na/c1-11-35(32-21(4)18-27(43-32)29-20(3)17-22(5)37(41,12-2)46-29)14-13-28(44-35)34(9)15-16-36(47-34)19-26(38)23(6)31(45-36)24(7)30(42-10)25(8)33(39)40;/h20-32,38,41H,11-19H2,1-10H3,(H,39,40);/q;+1/p-1/t20-,21-,22+,23+,24+,25-,26-,27+,28+,29?,30+,31-,32?,34-,35-,36?,37-;/m0./s1

Clave InChI: InChIKey=GAOZTHIDHYLHMS-KEOBGNEYSA-N

SMILES: C[C@@]1(O[C@]2(O[C@]([C@H]([C@H]([C@@H](C(O)=O)C)OC)C)([C@H](C)[C@@H](O)C2)[H])CC1)[C@@]3(O[C@@](CC)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H]

Sinónimos:

• 1,6-Dioxaspiro[4.5]decane, monensin deriv.
• 1,6-Dioxaspiro[4.5]decane-7-butyric acid, 2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-
• A 3823A
• Elancoban
• Monelan
• Monensic acid
• Monensin A
• Rumensin 90
• Rumensin CRC
• Stereoisomer of 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butanoic acid
• Monensin
• (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-{(2S,2'S,3'R,5R,5'S)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid
• sodium (2S,3R,4R)-4-[(2S,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(3S,5R)-5-[(3S,5R,6S)-6-ethyl-6-hydroxy-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methyl-pentanoate
• 4-(2-{2-Ethyl-5'-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl)-3-methoxy-2-methylpentanoate
• 2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid
• 1,6-dioxaspiro[4.5]decane-7-butanoato, 2-[2-ethyloctahydro-3'-methyl-5'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-, ion(1-)
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid
• MONENSIN(PURE)
• monensicacid
• Monensine sodium
• MONENSIN SODIUM
• MONENSIN SODIUM SALT
• gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph
• 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid
• a3823a
• 4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE
• MONENSINSODIUMSALT(30%)
• MONENSIN A SODIUM SALT
• MONENSIN NA
• Romensin

Monensin

CAS: 17090-79-8

Fórmula: C₃₆H₆₂O₁₁

Peso molecular: 670.87

Ref: 7W-GP7543

Monensin

CAS: 17090-79-8

Monensin, from Streptomyces cinnamonensis, inhibits Wnt/β-catenin. Potential anticancer agent.

Fórmula: C₃₆H₆₂O₁₁

Pureza: 98%

Forma y color: Crystals White Or Off-White Crystals

Peso molecular: 670.87

Ref: TM-T1033L

Monensin

CAS: 17090-79-8

Monensin is a polyether ionophore antibiotic, which is derived from the fermentation of the bacterium *Streptomyces cinnamonensis*. It operates by disrupting ion transport across biological membranes, primarily by facilitating the exchange of sodium and potassium ions. This ionophore action alters the osmotic balance in target cells, leading to their destabilization and death, particularly in Gram-positive bacteria and certain protozoa.

Fórmula: C₃₆H₆₂O₁₁

Pureza: Min. 95%

Peso molecular: 670.87 g/mol

Ref: 3D-FM31903