CAS 171599-83-0

citrato de sildenafil

Descripción:

citrato de sildenafil es un compuesto farmacéutico conocido principalmente por su uso en el tratamiento de la disfunción eréctil y la hipertensión arterial pulmonar. Funciona como un inhibidor selectivo de la fosfodiesterasa tipo 5 (PDE5), lo que potencia los efectos del óxido nítrico al aumentar los niveles de monofosfato de guanosina cíclico (cGMP) en el cuerpo cavernoso, lo que lleva a la vasodilatación y mejora el flujo sanguíneo. La sustancia aparece como un polvo cristalino blanco a blanco sucio y es soluble en agua, lo que la hace adecuada para la administración oral. Su fórmula molecular es C22H30N6O4S, y tiene un peso molecular de aproximadamente 474.6 g/mol. citrato de sildenafil se administra típicamente en forma de tabletas, con varias dosis disponibles, y se conoce por tener un inicio de acción relativamente rápido. Los efectos secundarios comunes pueden incluir dolores de cabeza, enrojecimiento y dispepsia, mientras que las contraindicaciones incluyen el uso de nitratos y ciertas condiciones cardiovasculares. En general, citrato de sildenafil ha tenido un impacto significativo en el tratamiento de la disfunción eréctil desde su introducción, mejorando la calidad de vida de muchas personas.

Fórmula: C₂₈H₃₈N₆O₁₁S

InChI: InChI=1/C21H28N6O4S/c1-4-6-16-18-19(25-24-16)21(28)23-20(22-18)15-13-14(7-8-17(15)31-5-2)32(29,30)27-11-9-26(3)10-12-27/h7-8,13H,4-6,9-12H2,1-3H3,(H,24,25)(H,22,23,28)

Clave InChI: InChIKey=DEIYFTQMQPDXOT-UHFFFAOYSA-N

SMILES: O(CC)C1=C(C=C(S(=O)(=O)N2CCN(C)CC2)C=C1)C=3NC4=C(C(=O)N3)N(C)N=C4CCC.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Sinónimos:

• 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one citrate
• 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-3-propyl-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Actra-R_x
• Alisiga
• Apodefil
• Caverta 100
• Edegra
• Granpidam
• Kamagra
• Maxifort
• Mysildecard
• Niagra Actra-R_x
• Penegra
• Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Sidenafil citrate
• Sildegra
• Sildigra
• Siligra
• Sollevare
• Tonafil
• Uk 92480
• Uk 92480-10
• Vega (pharmaceutical)
• Viagra
• Vigrex
• Zenegra
• Sildenafil citrate
• 1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine, Citrate
• SILDENAFIL CITRATE(RG)
• uk92480-10
• 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
• SildenafilCitrate/SildenafilBaseC28H38N6O11S
• 5(2-ETHOXY-5(4-METHYLPIPERAZINE)SULPHONYLPHENYL)-1
• din-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methyl-,2-hydroxy-1,2,3-propanetricarbo
• piperazine,1-((3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1h-pyrazolo(4,3-d)pyrimi
• SildenafilBaseC28H38N6O11S
• 1-[[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
• SILDANAFIL CITRATE (BULK)

Sildenafil Citrate

CAS: 139755-83-2, 171599-83-0

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 666.70

Ref: 3B-S0986

Sildenafil citrate

CAS: 171599-83-0

Forma y color: Neat

Ref: LP-SIL-984-CI-10

Sildenafil citrate, 1mg/ml in Methanol (as free base)

CAS: 171599-83-0

Forma y color: Single Solution

Ref: LP-SIL-984-CI-1LM

Sildenafil citrate

CAS: 171599-83-0

Forma y color: Neat

Ref: 61-FOR0254.00

SILDENAFIL FOR PEAK IDENTIFICATION CRS

CAS: 171599-83-0

SILDENAFIL FOR PEAK IDENTIFICATION CRS

Fórmula: C₂₈H₃₈N₆O₁₁S

Peso molecular: 666.6999

Ref: 41-Y0001891

SILDENAFIL CITRATE CRS

CAS: 171599-83-0

SILDENAFIL CITRATE CRS

Fórmula: C₂₈H₃₈N₆O₁₁S

Peso molecular: 666.6999

Ref: 41-Y0001578

Sildenafil Citrate

CAS: 171599-83-0

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Forma y color: White Off-White Crystalline Powder

Peso molecular: 474.20492

Ref: 45-1612561

Sildenafil citrate

CAS: 171599-83-0

Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.

Fórmula: C₂₈H₃₈N₆O₁₁S

Pureza: 99.59% - 99.97%

Forma y color: White Solid

Peso molecular: 666.70

Ref: TM-T0467

Sildenafil Citrate

CAS: 171599-83-0

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Forma y color: White To Off-White Solid

Peso molecular: 474.58 192.12

Ref: 4Z-S-061

Sildenafil citrate

CAS: 171599-83-0

Sildenafil citrate

Pureza: ≥98%

Peso molecular: 666.7g/mol

Ref: 54-BUP17834

Sildenafil citrate

CAS: 171599-83-0

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Pureza: ≥ 99.0% (dried basis)

Forma y color: White powder

Peso molecular: 666.70

Ref: 7W-GP3242

Sildenafil citrate

CAS: 171599-83-0

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Forma y color: Neat

Peso molecular: 666.70

Ref: 04-C16946500

Sildenafil Citrate

CAS: 171599-83-0

Forma y color: Neat

Ref: 86-MM0254.00

Sildenafil Citrate

Producto controlado

CAS: 171599-83-0

Stability Store in Freezer
Applications Sildenafil Citrate is an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996), Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998),

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Forma y color: White To Off-White

Peso molecular: 666.70

Ref: TR-S435000

Sildenafil Citrate-d3

Producto controlado

CAS: 171599-83-0

Fórmula: C₂₂H₂₇D₃N₆O₄S•(C₆H₈O₇)

Forma y color: Off-White

Peso molecular: 669.71

Ref: TR-S435004

Sildenafil citrate

CAS: 171599-83-0

Sildenafil is an inhibitor of phosphodiesterase type-5 (PDE-5). It is used in the treatment of erectile dysfunction. Sildenafil inhibits the enzyme phosphodiesterase type-5, which prevents the conversion of cyclic guanosine monophosphate to cyclic adenosine monophosphate, and this results in relaxation of smooth muscle cells and increased blood flow to the corpus cavernosum. The PDE-5 inhibitors are selective for human PDE-5 and do not inhibit PDEs 1, 2, 3, or 6. The inhibition of PDE-5 by sildenafil is reversible. Sildenafil has been shown to be a potent inhibitor of cyclase activity in vitro. br> The LC/MS/MS method was developed to measure the concentration of sildenafil in human serum. This analytical method provides a linear calibration curve with limits of quant

Fórmula: C₂₈H₃₈N₆O₁₁S

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 666.7 g/mol

Ref: 3D-FS27829

Sildenafil citrate - Bio-X ™

CAS: 171599-83-0

A potent selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE-5), thereby reducing the degradation rate of cGMP. Sildenafil is used to treat erectile dysfunction and pulmonary arterial hypertension.
Sildenafil citrate is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₈H₃₈N₆O₁₁S

Pureza: Min. 95%

Peso molecular: 666.7 g/mol

Ref: 3D-BS164405