
CAS 172822-29-6
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Encontrado 7 productos.
Aprepitant Related Compound B (3-[[(2S,3R)-2-[(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C23H21F7N4O3Forma y color:White Off-White Crystalline PowderPeso molecular:534.150193-[[(2S,3R)-2-[(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one ((S,R,S)-Aprepitant)
CAS:Producto controladoFórmula:C23H21F7N4O3Forma y color:NeatPeso molecular:534.43ent-aprepitant
CAS:<p>Aprepitant is a drug that belongs to the class of antiemetics. It is an antagonist of the neurokinin-1 receptor (NK-1R) and blocks the apical portion of the NK-1R, preventing binding of substance P. Aprepitant also has been shown to have a matrix effect on human pharmacokinetics in vitro and to inhibit p450 activity in human serum. This drug has been found to induce apoptosis by inhibiting the expression of pro-apoptotic proteins and activating pro-survival proteins. Aprepitant has also been shown to be effective in treating solid tumours, particularly colorectal cancer, with synergism with chemotherapy drugs such as trifluoroacetic acid.</p>Fórmula:C23H21F7N4O3Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:534.43 g/molent-Aprepitant-13C15N2
CAS:Producto controladoFórmula:CC22H21F715N2N2O3Forma y color:NeatPeso molecular:537.406






