CAS 17321-77-6
:clorhidrato de clomipramina
Descripción:
clorhidrato de clomipramina es un antidepresivo tricíclico utilizado principalmente en el tratamiento del trastorno obsesivo-compulsivo (TOC) y otros trastornos del estado de ánimo. Funciona inhibiendo la recaptación de neurotransmisores, particularmente serotonina y norepinefrina, mejorando así su disponibilidad en la hendidura sináptica. Este compuesto aparece como un polvo cristalino blanco a blanco sucio y es soluble en agua, lo que lo hace adecuado para la administración oral. clorhidrato de clomipramina tiene una vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Su perfil farmacológico incluye una variedad de efectos secundarios, como sedación, boca seca y posibles efectos cardiovasculares, lo que requiere un monitoreo cuidadoso en los pacientes. La sustancia está clasificada como un medicamento de prescripción y está sujeta a controles regulatorios debido a su potencial de efectos secundarios e interacciones con otros medicamentos. En general, clorhidrato de clomipramina es un agente terapéutico importante en psiquiatría, particularmente para pacientes con TOC resistente al tratamiento.
Fórmula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
Clave InChI:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Sinónimos:- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl
- ANAFRANIL HYDROCHLORIDE
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- CLOMIPRAMINE HYDROCHLORIDE
- Clomipraminhydrochlorid
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
- Chlomipramine
- 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
- 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
- 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
- f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
- CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
- 3-chloroimipraminehydrochloride
- CHLOROIMIPRAMINE HYDROCHLORIDE
- Ver más sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Se han encontrado 23 productos.
Clomipramine hydrochloride
CAS:Potent, selective 5-HT uptake blockerFórmula:C19H24Cl2N2Forma y color:White to pale yellow, Crystals or crystalline powderPeso molecular:351.32Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFórmula:C19H23ClN2HClPureza:99.6%Forma y color:White To Off-WhitePeso molecular:350.13165Clomipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeuFórmula:C19H23ClN2·HCIForma y color:White Yellow PowderPeso molecular:454.06727(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
CAS:Fórmula:C19H24Cl2N2Pureza:99%Forma y color:SolidPeso molecular:351.3133Clomipramine Hydrochloride
CAS:Clomipramine HydrochlorideFórmula:C19H23ClN2HClPureza:>99%Forma y color:SolidPeso molecular:351.31Clomipramine hydrochloride
CAS:Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.Fórmula:C19H23ClN2·HClPureza:99.04% - 99.47%Forma y color:SolidPeso molecular:351.31Clomipramine-13C-d3 HCl
CAS:Fórmula:C1813CH20D3ClN2·HClForma y color:White To Off-White SolidPeso molecular:318.87 36.46Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFórmula:C19H23ClN2·HClPureza:≥98%Peso molecular:351.31Clomipramine Hydrochloride (Standard)
CAS:Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.Fórmula:C19H23ClN2·HClForma y color:SolidPeso molecular:351.31Clomipramine Hydrochloride
CAS:Fórmula:C19H23ClN2·HClPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:351.32Clomipramine Hydrochloride
CAS:Producto controladoFórmula:C19H23ClN2·ClHForma y color:NeatPeso molecular:351.31Clomipramine hydrochloride
CAS:Fórmula:C19H23ClN2·HClPureza:98.0 - 102.0 % (dried basis)Forma y color:White or almost white crystalline powderPeso molecular:351.32Clomipramine Hydrochloride
CAS:Producto controladoApplications Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990), Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995), Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000), Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005),Fórmula:C19H23ClN2·ClHForma y color:NeatPeso molecular:351.31Clomipramine hydrochloride - Bio-X ™
CAS:Producto controladoClomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.
Fórmula:C19H24Cl2N2Pureza:Min. 95%Forma y color:White PowderPeso molecular:351.31 g/molClomipramine hydrochloride
CAS:Producto controladoClomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.Fórmula:C19H24Cl2N2Pureza:Min. 95%Forma y color:SolidPeso molecular:351.31 g/mol
![(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethy…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001YPT.jpg&w=3840&q=75)
