CAS 17321-77-6

clorhidrato de clomipramina

Descripción:

clorhidrato de clomipramina es un antidepresivo tricíclico utilizado principalmente en el tratamiento del trastorno obsesivo-compulsivo (TOC) y otros trastornos del estado de ánimo. Funciona inhibiendo la recaptación de neurotransmisores, particularmente serotonina y norepinefrina, mejorando así su disponibilidad en la hendidura sináptica. Este compuesto aparece como un polvo cristalino blanco a blanco sucio y es soluble en agua, lo que lo hace adecuado para la administración oral. clorhidrato de clomipramina tiene una vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Su perfil farmacológico incluye una variedad de efectos secundarios, como sedación, boca seca y posibles efectos cardiovasculares, lo que requiere un monitoreo cuidadoso en los pacientes. La sustancia está clasificada como un medicamento de prescripción y está sujeta a controles regulatorios debido a su potencial de efectos secundarios e interacciones con otros medicamentos. En general, clorhidrato de clomipramina es un agente terapéutico importante en psiquiatría, particularmente para pacientes con TOC resistente al tratamiento.

Fórmula: C₁₉H₂₄Cl₂N₂

InChI: InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H

Clave InChI: InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N

SMILES: C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl

Sinónimos:

• 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
• 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
• 3-Chloroimipramine hydrochloride
• 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
• 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
• Anafranil
• Anaphranil
• Anatranil
• Chlorimipramine hydrochloride
• Chloroimipram-ine HCl
• Chloroimipramine monohydrochloride
• Clomipramine HCl
• ANAFRANIL HYDROCHLORIDE
• 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
• CLOMIPRAMINE HYDROCHLORIDE
• Clomipraminhydrochlorid
• 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
• Chlomipramine
• 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
• 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
• 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
• f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
• f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
• CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
• 3-chloroimipraminehydrochloride
• CHLOROIMIPRAMINE HYDROCHLORIDE

Clomipramine hydrochloride

Producto controlado

CAS: 17321-77-6

Clomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.

Fórmula: C₁₉H₂₄Cl₂N₂

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 351.31 g/mol

Ref: 3D-FC20505

Clomipramine hydrochloride - Bio-X ™

Producto controlado

CAS: 17321-77-6

Clomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.

Fórmula: C₁₉H₂₄Cl₂N₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 351.31 g/mol

Ref: 3D-BC164325