CAS 175481-36-4

Lacosamida

Descripción:

Lacosamida es un compuesto farmacéutico que se utiliza principalmente como anticonvulsivo en el tratamiento de la epilepsia. Se clasifica como un aminoácido funcionalizado y es conocido por su capacidad para estabilizar las membranas neuronales e inhibir la descarga neuronal repetitiva. La fórmula química de Lacosamida es C15H18N2O2, y presenta una estructura única que incluye un anillo fenilo y un grupo funcional amida. Lacosamida actúa mejorando la inactivación de los canales de sodio dependientes de voltaje, lo que ayuda a reducir la excitabilidad de las neuronas. Se administra típicamente por vía oral o intravenosa y se absorbe bien en el tracto gastrointestinal. La sustancia tiene un perfil farmacocinético favorable, con una vida media relativamente larga, lo que permite una dosificación una o dos veces al día. Los efectos secundarios comunes pueden incluir mareos, náuseas y dolor de cabeza, pero generalmente es bien tolerado. Lacosamida también se está investigando para su posible uso en otros trastornos neurológicos, lo que refleja su amplio potencial terapéutico más allá de la epilepsia.

Fórmula: C₁₃H₁₈N₂O₃

InChI: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1

Clave InChI: InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N

SMILES: C(NC([C@H](NC(C)=O)COC)=O)C1=CC=CC=C1

Sinónimos:

• (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
• (2R)-2-Acetamido-N-benzyl-3-methoxypropanamide
• (2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
• (R)-2-Acetamido-N-benzyl-3-methoxypropionamide
• (R)-2-acetamido-N-benzyl-3-methoxypropanamide
• Add 243037
• Erlosamide
• Harkoseride
• Lacosamide UCB
• Lacoset
• Lacoset 50
• N~2~-acetyl-N-benzyl-O-methyl-D-serinamide
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (R)-
• Spm 927

Lacosamide

CAS: 175481-36-4

Forma y color: Neat

Ref: 61-FOR3640.00

Lacosamide 1.0 mg/ml in Acetonitrile

Producto controlado

CAS: 175481-36-4

Forma y color: Single Solution

Ref: 61-AMP3640.00-11

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 175481-36-4

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001973

LACOSAMIDE CRS

CAS: 175481-36-4

LACOSAMIDE CRS

Ref: 41-Y0001982

Lacosamide

CAS: 175481-36-4

Fórmula: C₁₃H₁₈N₂O₃

Pureza: (HPLC) ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 250.29

Ref: 7W-GP3690

Lacosamide

CAS: 175481-36-4

Fórmula: C₁₃H₁₈N₂O₃

Forma y color: White To Off-White Solid

Peso molecular: 250.30

Ref: 4Z-L-281

Lacosamide-d3 (Acetyl-d3)

CAS: 175481-36-4

Fórmula: C₁₃H₁₅D₃N₂O₃

Forma y color: White To Off-White Solid

Peso molecular: 253.32

Ref: 4Z-L-283

Lacosamide

Producto controlado

CAS: 175481-36-4

Forma y color: Neat

Ref: 86-MM3640.00

Lacosamide

Producto controlado

CAS: 175481-36-4

Applications Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Fórmula: C₁₃H₁₈N₂O₃

Forma y color: Off-White

Peso molecular: 250.29

Ref: TR-L098500

Lacosamide - Bio-X ™

Producto controlado

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Fórmula: C₁₃H₁₈N₂O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 250.29 g/mol

Ref: 3D-BL164605

Lacosamide

Producto controlado

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Fórmula: C₁₃H₁₈N₂O₃

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 250.29 g/mol

Ref: 3D-FL24825

Lacosamide-d6

Producto controlado

CAS: 175481-36-4

Applications Labelled Lacosamide (L098500). Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Fórmula: C₁₃D₆H₁₂N₂O₃

Forma y color: Neat

Peso molecular: 256.331

Ref: TR-L098503

Lacosamide CV ((+)-(R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide)

Producto controlado

CAS: 175481-36-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Fórmula: C₁₃H₁₈N₂O₃

Forma y color: White Light Yellow Powder

Peso molecular: 250.13174

Ref: 45-1357103