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CAS 17575-21-2

:

lanatósido B

Descripción:
lanatósido B es un glucósido cardíaco derivado de las hojas de la planta Digitalis lanata, comúnmente conocida como dedalera lanosa. Se caracteriza por su capacidad para inhibir la enzima Na+/K+ ATPasa, lo que lleva a un aumento de las concentraciones intracelulares de sodio y calcio, mejorando en última instancia la contractilidad cardíaca. Esta propiedad hace que lanatósido B sea útil en el tratamiento de ciertas afecciones cardíacas, como la insuficiencia cardíaca y la fibrilación auricular. El compuesto tiene una estructura compleja, con un núcleo esteroide que presenta múltiples grupos hidroxilo y una porción de azúcar, lo que contribuye a su solubilidad y actividad biológica. lanatósido B se administra típicamente de manera controlada debido a su estrecho índice terapéutico, lo que significa que la diferencia entre las dosis terapéuticas y tóxicas es pequeña. Además, puede presentar efectos secundarios como trastornos gastrointestinales y arritmias, lo que requiere un monitoreo cuidadoso de los pacientes que reciben este medicamento. En general, lanatósido B es un compuesto importante en farmacología, particularmente en cardiología, debido a sus potentes efectos sobre la función cardíaca.
Fórmula:C49H76O20
InChI:InChI=1/C49H76O20/c1-21-43(67-37-16-31(53)44(22(2)62-37)68-38-17-33(64-24(4)51)45(23(3)63-38)69-46-42(58)41(57)40(56)34(19-50)66-46)30(52)15-36(61-21)65-27-9-11-47(5)26(14-27)7-8-29-28(47)10-12-48(6)39(25-13-35(55)60-20-25)32(54)18-49(29,48)59/h13,21-23,26-34,36-46,50,52-54,56-59H,7-12,14-20H2,1-6H3/t21-,22-,23-,26-,27+,28+,29-,30+,31+,32+,33+,34-,36+,37+,38+,39+,40-,41+,42-,43-,44-,45-,46+,47+,48-,49+/m1/s1
Clave InChI:InChIKey=XVAPNQFQPDAROQ-CAPSWCROSA-N
SMILES:O[C@@]12[C@@](C)([C@H]([C@@H](O)C1)C=3COC(=O)C3)CC[C@]4([C@]2(CC[C@]5([C@]4(C)CC[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](O[C@H]8C[C@H](OC(C)=O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](C)O8)[C@@H](C)O7)[C@@H](C)O6)C5)[H])[H])[H]
Sinónimos:
  • (3beta,5beta,16beta)-3-{[beta-D-glucopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-14,16-dihydroxycard-20(22)-enolide
  • (3beta,5beta,9xi,16alpha)-3-{[hexopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl]oxy}-14,16-dihydroxycard-20(22)-enolide
  • (3β,5β,16β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14,16-dihydroxycard-20(22)-enolide
  • 3-((O-beta-D-Glucopyranosyl-(1-4)-O-3-O-acetyl-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-14,16-dihydroxycard-20(22)-enolide (3beta,5beta,16beta)-
  • 3-{[hexopyranosyl-(1->4)-3-O-acetyl-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl]oxy}-14,16-dihydroxycard-20(22)-enolide
  • 5β-Card-20(22)-enolide, 3β-[[O-[O-(O-glucosyldigitoxosyl)digitoxosyl]digitoxosyl]oxy]-14,16β-dihydroxy-, acetate
  • Brn 0078394
  • Card-20(22)-enolide, 3-((O-beta-D-glucopyranosyl-(1-4)-O-3-O-acetyl-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-14,16-dihydroxy-, (3beta,5beta,16beta)- (9CI)
  • Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-14,16-dihydroxy-, (3β,5β,16β)-
  • Digilanid B
  • Ver más sinónimos
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Pureza (%)
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90
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95
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100
Encontrado 4 productos.
  • Lanatoside B
    Extrasynthese
    + Info

    Lanatoside B

    CAS:
    Lanatoside B analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
    Fórmula:C49H76O20
    Pureza:(HPLC) ≥85%
    Forma y color:Powder
    Peso molecular:985.14

    Ref: 11-0816

    5mg
    171,00€
  • Lanatoside B
    Targetmol
    + Info

    Lanatoside B

    CAS:
    Lanatoside B is a natural product from Polygonum lapathifolium.
    Fórmula:C49H76O20
    Pureza:98%
    Forma y color:Solid
    Peso molecular:985.12

    Ref: TM-TN1850

  • Lanatoside B
    TRC
    + Info

    Lanatoside B

    Producto controlado
    CAS:
    Fórmula:C49H76O20
    Forma y color:Off-White
    Peso molecular:985.12

    Ref: TR-L177393

    25mg
    5.147,00€
  • Lanatoside B
    Biosynth
    + Info

    Lanatoside B

    CAS:
    <p>Lanatoside B is a cardiac glycoside, which is a type of compound obtained from the leaves of the Digitalis lanata plant, commonly known as woolly foxglove. This compound belongs to a class of organic substances known for their potent effects on the heart's contractile capability. The primary mode of action of Lanatoside B involves inhibiting the sodium-potassium ATPase enzyme in cardiac tissues. This inhibition leads to an increase in intracellular sodium concentration, which subsequently boosts calcium ions available for myocardial contraction via the sodium-calcium exchange mechanism.</p>
    Fórmula:C49H76O20
    Pureza:Min. 95%
    Peso molecular:985.12 g/mol

    Ref: 3D-FL137800

    1mg
    336,00€
    2mg
    473,00€
    5mg
    798,00€
    10mg
    1.190,00€
    25mg
    2.074,00€