CAS 17685-04-0

Etil β-D-glucurónido

Descripción:

Etil β-D-glucurónido (EtG) es un metabolito del etanol, formado a través de la conjugación del etanol con ácido glucurónico. Es un compuesto incoloro y soluble en agua que a menudo se utiliza como biomarcador del consumo de alcohol debido a su presencia en la orina y otros fluidos biológicos después de la ingesta de etanol. EtG se caracteriza por su estabilidad, lo que permite que se detecte durante un período más prolongado en comparación con el etanol mismo, lo que lo convierte en una herramienta útil en las pruebas de alcohol. El compuesto es no volátil y tiene un peso molecular relativamente bajo. Su síntesis implica la acción enzimática de UDP-glucuronosiltransferasas, que facilitan la transferencia de ácido glucurónico a varios sustratos, incluido el etanol. Etil β-D-glucurónido también es de interés en farmacología y toxicología, ya que puede proporcionar información sobre el metabolismo del alcohol y sus efectos en el cuerpo. Debido a su formación específica a partir del etanol, sirve como un indicador confiable del consumo reciente de alcohol, ayudando en investigaciones clínicas y forenses.

Fórmula: C₈H₁₄O₇

InChI: InChI=1S/C8H14O7/c1-2-14-8-5(11)3(9)4(10)6(15-8)7(12)13/h3-6,8-11H,2H2,1H3,(H,12,13)/t3-,4-,5+,6-,8+/m0/s1

Clave InChI: InChIKey=IWJBVMJWSPZNJH-UQGZVRACSA-N

SMILES: C(O)(=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OCC)O1

Sinónimos:

• 6-Ethoxy-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylicAcid
• Ba 2829
• Ethyl -D-glucuronide
• Ethyl Glucuronide
• Ethyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucuronide
• Glucopyranosiduronic acid, ethyl, β-<span class="text-smallcaps">D</span>-
• ethyl D-glucopyranosiduronic acid
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-Glucuronide
• β-D-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-glucopyranosiduronic acid
• Ethyl β-D-glucosiduronic acid

Ethyl-β-D-glucuronide, 1mg/ml in Methanol

CAS: 17685-04-0

Forma y color: Single Solution

Ref: LP-EGL-332-1LM

Ethyl-β-D-glucuronide

CAS: 17685-04-0

Forma y color: Neat

Ref: LP-EGL-332-10

β-D-Glucopyranosiduronic acid, ethyl

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Pureza: 95%

Forma y color: Solid

Peso molecular: 222.1926

Ref: IN-DA0024Z7

Ethyl b-D-glucuronide, 1mg/ml solution in Methanol

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Peso molecular: 222.19

Ref: 7W-GW8904

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide

Pureza: ≥98%

Peso molecular: 222.19g/mol

Ref: 54-BUP01629

Ethyl b-D-glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 222.19

Ref: 7W-GC5234

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide (Ethyl-β-D-glucuronide) is a non-oxidized ethanol metabolite that is a biomarker of chronic alcohol consumption.

Fórmula: C₈H₁₄O₇

Pureza: 99.56%

Forma y color: Off-White Solid

Peso molecular: 222.19

Ref: TM-T11242

Ethyl D-Glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Peso molecular: 222.20

Ref: 4Z-A-862

Ethyl b-D-Glucuronide (1 mg/mL in Methanol)

Producto controlado

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Forma y color: Colourless

Peso molecular: 222.19

Ref: TR-KIT8320

Ethyl β-D-Glucuronide

CAS: 17685-04-0

Fórmula: C₈H₁₄O₇

Forma y color: White To Beige

Peso molecular: 222.19

Ref: TR-E918425

Ethyl β-D-glucuronide

CAS: 17685-04-0

Ethyl β-D-glucuronide (EBG) is a metabolite of ethanol that is formed by the conjugation of glucuronic acid to ethanol in the liver. EBG has been shown to be a potential biomarker for alcohol consumption, as it can be detected in urine and blood. The presence of this molecule has also been associated with an increased risk of developing type 2 diabetes mellitus, cardiovascular disease, and cancer. EBG may also have pharmacological effects as it has been shown to inhibit lipid oxidation and increase insulin sensitivity. This molecule can be extracted from human serum using solid phase microextraction

Fórmula: C₈H₁₄O₇

Pureza: Min. 98 Area-%

Forma y color: Slightly Brown Powder

Peso molecular: 222.19 g/mol

Ref: 3D-ME07200

Ethyl glucuronide

CAS: 17685-04-0

Pureza: 98%

Peso molecular: 222.07

Ref: 10-F557140

D3-Ethyl β-D-glucuronide

CAS: 17685-04-0

D3-Ethyl β-D-glucuronide is a metabolite of ethanol. Detection of this compound may be used to diagnose alcohol consumption during pregnancy. The detection time is approximately 5 hours after a single drink. D3-Ethyl β-D-glucuronide can be reliably detected in maternal blood using solid phase microextraction and LC-MS/MS methods. The body mass index (BMI) can be used to determine the risk for alcohol consumption during pregnancy, with higher BMIs indicating an increased risk. Logistic regression models were created to estimate the probability of D3-Ethyl β-D glucuronide being present in maternal blood and the probability of alcohol consumption during pregnancy given a positive result. These models were then used to create diagnostic tools that are sensitive enough for clinical use.

Fórmula: C₈H₁₁D₃O₇

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 225.21 g/mol

Ref: 3D-ME29306