CAS 17692-51-2

metergolina

Descripción:

metergolina es un compuesto químico clasificado como un antagonista del receptor de serotonina, que se dirige principalmente al subtipo de receptor 5-HT2. Se conoce por sus posibles aplicaciones en el campo de la neurociencia y la psicofarmacología, particularmente en el estudio de trastornos del estado de ánimo y condiciones psicóticas. metergolina exhibe una estructura compleja que incluye un moiety de indol, que es característico de muchos compuestos relacionados con la serotonina. La sustancia se administra típicamente en entornos de investigación, y su perfil farmacológico sugiere que puede influir en varios sistemas de neurotransmisores, afectando potencialmente el estado de ánimo y la percepción. metergolina ha sido investigado por sus efectos en las vías de serotonina tanto centrales como periféricas, contribuyendo a su interés en contextos terapéuticos. Sin embargo, al igual que muchos compuestos en esta categoría, también puede presentar efectos secundarios y requiere una cuidadosa consideración en términos de dosificación y administración. Al igual que con cualquier agente farmacológico, la investigación continua es esencial para comprender completamente sus mecanismos de acción y beneficios terapéuticos potenciales.

Fórmula: C₂₅H₂₉N₃O₂

InChI: InChI=1/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/p+1/t18-,21+,23+/m0/s1

Clave InChI: InChIKey=WZHJKEUHNJHDLS-QTGUNEKASA-N

SMILES: CN1C2=C3C([C@@]4([C@@](CC3=C1)(N(C)C[C@H](CNC(OCC5=CC=CC=C5)=O)C4)[H])[H])=CC=C2

Sinónimos:

• (((8-beta)-1,6-Dimethylergolin-8-yl)methyl)carbamic acid phenylmethyl ester
• (+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester
• (+)-N-Carboxy-1-methyl-9,10-dihydrolysergamide benzyl ester
• 1,6-Dimethyl-8-beta-carbobenzyloxaminomethyl-10-alpha-ergoline
• 1-Methyl-8-beta-carbobenzyloxyaminomethyl-10-alpha-ergoline
• 1-Methyl-N-carbobenzyloxydihydro-D-lysergamin
• 8β-Carbobenzyloxyaminomethyl-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carbobenzoxyamino)methyl]-1,6-dimethyl-10α-ergoline
• <span class="text-smallcaps">D</span>-8β-[(Carboxyamino)methyl]-1,6-dimethylergoline I benzyl ester
• <span class="text-smallcaps">D</span>-N-Carbobenzoxydihydro-1-methyllysergamine I
• <span class="text-smallcaps">D</span>-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• <span class="text-smallcaps">D</span>-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aα-indolo[4,3-fg]quinolin-9β-yl)methyl]carbamic acid benzyl ester
• Ahr 3009
• Benzyl 1,6-dimethylergolin-8beta-ylmethylcarbamat
• Benzyl {[(5Xi,10Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl}Carbamate
• Benzyl {[(8Beta)-1,6-Dimethylergolin-8-Yl]Methyl}Carbamate
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, benzyl ester
• Carbamic acid, (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester (9CI)
• Carbamic acid, (((8beta)-1,6-dimethylergolin-8-yl)methyl)-, phenylmethyl ester
• Carbamic acid, ((1,6-dimethylergolin-8-beta-yl)methyl)-, benzyl ester
• Carbamic acid, N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Carbamic acid, [(1,6-dimethylergolin-8β-yl)methyl]-, benzyl ester
• Carbamic acid, [[(8β)-1,6-dimethylergolin-8-yl]methyl]-, phenylmethyl ester
• Contralac
• D-8-beta-((Carbobenzoxyamino)methyl)-1,6-dimethyl-10-alpha-ergoline
• D-8-beta-((Carboxyamino)methyl)-1,6-dimethylergoline I benzyl ester
• D-N-Carbobenzoxydihydro-1-methyllysergamine I
• D-N-Carboxydihydro-1-methyllysergamine I benzyl ester
• Ergoline, carbamic acid deriv.
• Fi 6337
• Indolo[4,3-fg]quinoline, carbamic acid deriv.
• Liserdol
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester
• Lysergamine, N-carboxy-9,10-dihydro-1-methyl-, benzyl ester (7CI)
• MCE
• Metergolin
• Metergolina
• Metergolina [DCIT]
• Metergolina [Spanish]
• Metergoline [INN:BAN]
• Metergolinum
• Metergolinum [INN-Latin]
• Metergolinum [Latin]
• Methergoline
• Substance 355/255
• Unii-1501393Ly5
• Metergoline
• [((8BETA)-1,6-DIMETHYLERGOLIN-8-YL)METHYL]CARBAMIC ACID PHENYLMETHYL ESTER
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicaciphenylmethylest
• d-n-carbobenzoxydihydro-1-methyllysergaminei
• ((1,6-dimethylergolin-8-beta-yl)methyl)-carbamicacibenzylester
• d-n-carboxydihydro-1-methyllysergamineibenzylester
• ahr3009
• N-CBZ-[(8BETA)-1,6-DIMETHYLERGOLIN-8-YL]METHYLAMINE
• (((8-beta)-1,6-dimethylergolin-8-yl)methyl)-carbamicacibenzylester
• METERGOLINE PHENYLMETHYL ESTER

Metergoline

CAS: 17692-51-2

Fórmula: C₂₅H₂₉N₃O₂

Pureza: 99%

Forma y color: Solid

Peso molecular: 403.5167

Ref: IN-DA0078UU

Metergoline

CAS: 17692-51-2

Metergoline

Pureza: ≥98%

Peso molecular: 403.52g/mol

Ref: 54-BUP16416

Metergoline

CAS: 17692-51-2

Fórmula: C₂₅H₂₉N₃O₂

Peso molecular: 403.52

Ref: 7W-GP3682

Metergoline

CAS: 17692-51-2

Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.

Fórmula: C₂₅H₂₉N₃O₂

Pureza: 99.83% - 99.97%

Forma y color: Solid

Peso molecular: 403.52

Ref: TM-T4008

Metergoline

CAS: 17692-51-2

Applications Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.
References Aulakh, et al.: J. Pharmacol. Exp. Ther., 263, 588 (1992), Miller, et al.: Eur. J. Pharmacol., 227, 99 (1992),

Fórmula: C₂₅H₂₉N₃O₂

Forma y color: Off White Powder

Peso molecular: 403.5167

Ref: TR-M226270

[(8b)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester

CAS: 17692-51-2

Ergolines are a class of drugs that bind to serotonin receptors. The ergoline derivative [(8b)-1,6-dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester (DMPE) is a potent and selective 5-hydroxytryptamine (5-HT) receptor antagonist. DMPE has been shown to have the ability to increase serum prolactin levels in rats and antagonize the effects of metergoline in monkeys. It also reduces blood pressure in animals by blocking the vasoconstrictor effect of 5-HT on vascular smooth muscle cells.

Fórmula: C₂₅H₂₉N₃O₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 403.52 g/mol

Ref: 3D-FM12444