CAS 177325-13-2

Clorhidrato de Levofloxacina

Descripción:

Clorhidrato de Levofloxacina es un antibiótico sintético que pertenece a la clase de las fluoroquinolonas, utilizado principalmente para tratar una variedad de infecciones bacterianas. Se caracteriza por su actividad de amplio espectro contra bacterias Gram-positivas y Gram-negativas, lo que lo hace efectivo para infecciones del tracto respiratorio, infecciones del tracto urinario e infecciones cutáneas. El compuesto es una molécula quiral, siendo su forma levorotatoria el isómero activo, lo que mejora su eficacia antibacteriana en comparación con su contraparte racémica. Clorhidrato de Levofloxacina se administra típicamente por vía oral o intravenosa y es conocido por su buena biodisponibilidad. Su mecanismo de acción implica la inhibición de la girasa del ADN bacteriano y la topoisomerasa IV, enzimas cruciales para la replicación y transcripción del ADN. La sustancia generalmente es bien tolerada, aunque puede causar efectos secundarios como trastornos gastrointestinales, efectos en el sistema nervioso central y, en casos raros, daño en los tendones. Debido a su potencial para desarrollar resistencia, es importante usar levofloxacino de manera juiciosa y de acuerdo con los patrones de susceptibilidad.

Fórmula: C₁₈H₂₀FN₃O₄·HCl

InChI: InChI=1/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1

Clave InChI: InChIKey=CAOOISJXWZMLBN-PPHPATTJSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@H](C)N3C=C1C(O)=O.Cl

Sinónimos:

• (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride
• (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (S)-
• Carboxylic Acid Monohydrochloride
• Levofloxacin Hcl
• LevofloxacinHydrochloride
• Weilisu
• Levofloxacin hydrochloride
• -7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• -9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)
• usp27 99% Levofloxacin white powder Antibacterial
• Levofloxacin white powder Antibacterial
• 3S)-9-Fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid Monohydrochlori
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-,hydrochloride (1:1), (3S)-

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-

CAS: 177325-13-2

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 397.8284

Ref: IN-DA00258K

Levofloxacin hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·HCl

Pureza: ≥ 89.0% (C18H20FN3O4, dried basis)

Forma y color: Off-white to pale beige or light-yellow powder

Peso molecular: 397.9

Ref: 7W-GA2496

Levofloxacin Hydrochloride

CAS: 177325-13-2

Levofloxacin Hydrochloride

Pureza: 99%

Peso molecular: 397.83g/mol

Ref: 54-PC109232

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin hydrochloride

Pureza: ≥98%

Peso molecular: 397.8g/mol

Ref: 54-BUP19621

Levofloxacin Hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·HCl

Pureza: >95.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 397.83

Ref: 3B-L0460

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 99.78% - 99.98%

Forma y color: Solid

Peso molecular: 397.8

Ref: TM-T8747

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Levofloxacin has been shown to be effective against many infectious diseases, including urinary tract infections and some types of pneumonia. Levofloxacin also has inhibitory properties against gram-positive bacteria such as Streptococcus pyogenes and Staphylococcus aureus. The mechanism of action is not fully understood, but it is believed that levofloxacin interferes with protein synthesis by binding to the 30S subunit of the bacterial ribosome. The drug also binds to benzalkonium chloride (BAK) in wastewater treatment systems, which may contribute to its effectiveness in these

Fórmula: C₁₈H₂₀FN₃O₄•HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 397.83 g/mol

Ref: 3D-FL104256

(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₁ClFN₃O₄

Pureza: 98%

Forma y color: Solid, No data available.

Peso molecular: 397.83

Ref: 10-F054449

Levofloxacin Hydrochloride

CAS: 177325-13-2

Fórmula: C₁₈H₂₀FN₃O₄·(HCl)

Forma y color: White To Light Beige

Peso molecular: 361.37 + (36.46)

Ref: TR-L360258