CAS 1784-03-8

L-Arginina, N2-[(4-metilfenil)sulfonil]-, éster metílico, clorhidrato (1:1)

Descripción:

L-Arginina, N2-[(4-metilfenil)sulfonil]-, éster metílico, clorhidrato (1:1) es un compuesto químico que presenta una combinación de un aminoácido, L-arginina, y un grupo sulfonilo unido a un moiety de metilfenilo. Este compuesto se caracteriza por su estructura de aminoácido básico, que incluye un grupo guanidinio, contribuyendo a su papel en varios procesos biológicos, como la síntesis de proteínas y la producción de óxido nítrico. La presencia del éster metílico indica que es un derivado de L-arginina, que puede mejorar su solubilidad y biodisponibilidad. La forma de clorhidrato sugiere que es una sal, que típicamente mejora la estabilidad y las propiedades de manejo. Este compuesto puede exhibir diversas actividades farmacológicas, incluyendo roles potenciales en la salud cardiovascular y la función inmunológica. Su grupo sulfonilo también puede influir en su reactividad e interacción con objetivos biológicos. En general, L-Arginina, N2-[(4-metilfenil)sulfonilo]-, éster metílico, clorhidrato es de interés tanto en la investigación bioquímica como en aplicaciones terapéuticas potenciales.

Fórmula: C₁₄H₂₂N₄O₄S·ClH

InChI: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

Clave InChI: InChIKey=JIQFFACVQXXHMY-YDALLXLXSA-N

SMILES: S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1.Cl

Sinónimos:

• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride
• Arginine, N²-(p-tolylsulfonyl)-, methyl ester, monohydrochloride, <span class="text-smallcaps">L</span>-
• N-alpha-Toluenesulfonylarginine methyl ester hydrochloride
• N-alpha-Tosyl-L-arginine methyl ester hydrochloride
• N-p-Tosyl-L-arginine methyl ester hydrochloride
• N-α-p-Tosyl-L-arginine methyl ester hydrochloride
• N^α-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Nalpha-(4-Toluenesulfonyl)-L-Arginine Methyl Ester Hydrochloride
• Tame
• Tos-Arg-OMe . HCl
• Tos-Arg-OMe・HCl
• Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Tosylarginine methyl ester hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]-L-ornithinate hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]ornithinate hydrochloride
• na-P-tosyl-L-arginine methyl*ester hydrochloride
• α-N-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• α-N-Tosyl-L-arginine methyl ester hydrochloride
• Nα-Tosyl-L-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride

Nα-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: >98.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 378.87

Ref: 3B-T0330

Tos-Arg-OMe · HCl

CAS: 1784-03-8

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: > 99%

Forma y color: White Powder

Peso molecular: 378.88

Ref: 01-4002251

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

CAS: 1784-03-8

Fórmula: C₁₄H₂₃ClN₄O₄S

Pureza: 98%

Forma y color: Solid

Peso molecular: 378.8748

Ref: IN-DA0025ZQ

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Fórmula: C₁₄H₂₃ClN₄O₄S

Pureza: 99.11% - 99.21%

Forma y color: White Fine Crystalline Powder

Peso molecular: 378.87

Ref: TM-T1731

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride

Pureza: ≥95%

Peso molecular: 378.87g/mol

Ref: 54-BUP17017

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

Pureza: 98%

Peso molecular: 378.87g/mol

Ref: 54-OR1014507

TAME Hydrochloride

CAS: 1784-03-8

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: ≥ 98.0%

Forma y color: White to almost white powder

Peso molecular: 378.87

Ref: 7W-GM4942

N-α-Tosyl-L-arginine methyl ester hydrochloride

CAS: 1784-03-8

N-alpha-Tosyl-L-arginine methyl ester hydrochloride is a potent inhibitor of the serine protease leishmania. It inhibits the enzyme by binding to its active site and interfering with the enzymatic reaction. This drug has been shown to be effective in treating bladder infections caused by leishmania, although it can cause a decrease in responsiveness in an animal model. N-alpha-Tosyl-L-arginine methyl ester hydrochloride also has anti-HIV activities, which may be due to its ability to inhibit HIV replication. The drug is most likely absorbed through the apical surface of the bladder epithelium and then diffuses into the extracellular space, where it inhibits key enzymes involved in viral replication.

Fórmula: C₁₄H₂₂N₄O₄S·HCl

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 378.88 g/mol

Ref: 3D-FT55915

TAME hydrochloride

CAS: 1784-03-8

Pureza: 98%

Peso molecular: 378.87

Ref: 10-M03112

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Applications N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.
References Hummel, B. et al.: Can. J. Biochem. Physiol., 37, 1393 (1959); Matsuda, Y. et al.: J. Biochem. 80, 671 (1976);

Fórmula: C₁₄H₂₃ClN₄O₄S

Forma y color: Neat

Peso molecular: 378.87

Ref: TR-T570000

TAME hydrochloride

CAS: 1784-03-8

Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.

Fórmula: C₁₄H₂₂N₄O₄S·ClH

Pureza: Min. 95%

Peso molecular: 378.87 g/mol

Ref: 3D-STR-3003