CAS 1811-31-0

GalNAc

Descripción:

GalNAc, o N-acetilgalactosamina, es un aminoazúcar y un derivado de la galactosa. Se caracteriza por la presencia de un grupo acetilo unido al grupo amino en la molécula de galactosa. Este compuesto desempeña un papel crucial en varios procesos biológicos, particularmente en la síntesis de glicoproteínas y glicolípidos, donde actúa como un bloque de construcción para carbohidratos complejos. GalNAc también está involucrado en procesos de señalización y reconocimiento celular, influyendo en las interacciones celulares y las respuestas inmunitarias. Se encuentra típicamente en forma de un polvo cristalino blanco y es soluble en agua. El compuesto es no tóxico y se utiliza en diversas aplicaciones bioquímicas, incluyendo investigación y desarrollo terapéutico. Sus propiedades estructurales le permiten participar en varias reacciones enzimáticas, lo que lo hace significativo en el estudio de la glicobiología. En general, GalNAc es un componente esencial en la bioquímica de los organismos vivos, contribuyendo a la complejidad y funcionalidad de las estructuras celulares.

Fórmula: C₈H₁₅NO₆

InChI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8-/m0/s1

Clave InChI: InChIKey=MBLBDJOUHNCFQT-OSMVPFSASA-N

SMILES: [C@H]([C@H]([C@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O

Sinónimos:

• 2-(Acetylamino)-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-(Acetylamino)-2-deoxy-D-galactose
• 2-Acetamido-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-Acetamido-2-deoxy-D-galactose
• 2-Deoxy-2-acetamido-<span class="text-smallcaps">D</span>-galactose
• 2-Deoxy-2-acetamido-D-galactose
• 2-N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• 2-N-Acetyl-D-galactosamine
• <span class="text-smallcaps">D</span>-Galactose, 2-(acetylamino)-2-deoxy-
• <span class="text-smallcaps">D</span>-N-Acetylgalactosamine
• D-N-Acetylgalactosamine
• GalNAc
• Galactosamine, N-acetyl-, <span class="text-smallcaps">D</span>-
• Galactosamine, N-acetyl-, D-
• Galactose, 2-acetamido-2-deoxy-, <span class="text-smallcaps">D</span>-
• Galactose, 2-acetamido-2-deoxy-, D-
• N-Acetyl-2-amino-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• N-Acetyl-2-amino-2-deoxy-D-galactose
• N-Acetyl-2-amino-2-deoxygalactose
• N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• N-Acetyl-D-galactosamine
• N-Acetyl-β-D-galaktosamin
• N-Acetylchondrosamine
• N-Acetylgalactosamine
• N-acetil-β-D-galactosamina
• N-acetyl-β-D-galactosamine

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine is the initial O-linked sugar to many serine and threonine residues in protein glycosylation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The o

Fórmula: C₈H₁₅NO₆

Forma y color: Crystals or crystalline powder, White

Peso molecular: 221.21

Ref: 02-J66095

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Fórmula: C₈H₁₅NO₆

Pureza: 97%

Forma y color: White Solid

Peso molecular: 221.20779

Ref: 54-BIM1065

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Fórmula: C₈H₁₅NO₆

Pureza: 95%

Forma y color: White Solid-Powder

Peso molecular: 221.20779

Ref: 54-OR7700T

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine

Fórmula: C₈H₁₅NO₆

Pureza: ≥98%

Peso molecular: 221.21

Ref: 54-BUP18207

N-Acetyl-D-galactosamine

CAS: 1811-31-0

Fórmula: C₈H₁₅NO₆

Pureza: 98%

Forma y color: Solid

Peso molecular: 221.2078

Ref: IN-DA0022OP

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).

Fórmula: C₈H₁₅NO₆

Pureza: 99.79% - 99.93%

Forma y color: White Crystalline Powder

Peso molecular: 221.21

Ref: TM-T4708

N-Acetyl-D-galactosamine

Producto controlado

CAS: 1811-31-0

Applications N-Acetyl-D-galactosamine (cas# 1811-31-0) is a compound useful in organic synthesis.
References Nakajima, M., et al.: App. Microbiol. Biotechnol., 83, 109 (2009), Singh, S., et al.: Mol. Immunol., 46, 1240 (2009),

Fórmula: C₈H₁₅NO₆

Forma y color: Neat

Peso molecular: 221.2078

Ref: TR-A177000

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn'sdisease patients is significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohn's disease (Inoue, 2012).

Fórmula: C₈H₁₅NO₆

Pureza: Min. 98%

Forma y color: White Powder

Peso molecular: 221.21 g/mol

Ref: 3D-MA04390

N-acetyl-D-galactosamine-[UL-13C6]

CAS: 1811-31-0

Ref: BE-MD-8209

N-((2R,3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide

CAS: 1811-31-0

Fórmula: C₈H₁₅NO₆

Pureza: 80%

Forma y color: Solid

Peso molecular: 221.209

Ref: 10-F239286

D-N-Acetylgalactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Fórmula: C₈H₁₅NO₆

Pureza: 95%

Peso molecular: 221.21

Ref: IN-DG5483

N-Acetyl-D-galactosamine, plant-based

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose. It forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.This N-Acetyl-D-galactosamine product (MA184543) is plant-based and produced synthetically from Arabic gum.GalNAc clusters and derivatives, typically composed of three (or more) GalNAc moieties arranged in a specific spatial configuration, are a powerful tool for targeted delivery of nucleic acid therapeutics, specifically in liver targeted therapies. These multivalent ligands effectively bind and internalize via the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatocytes.

Fórmula: C₈H₁₅NO₆

Pureza: Min. 97 Area-%

Peso molecular: 221.21 g/mol

Ref: 3D-MA184543

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).

Fórmula: C₈H₁₅NO₆

Pureza: Min. 99.0 Area-%

Peso molecular: 221.21 g/mol

Ref: 3D-A-1170