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CAS 1816990-29-0

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K-Opioid receptor agonist-1

Fórmula:C22H29Cl2N3O3
Sinónimos:
  • K-Opioid receptor agonist-1
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    K-Opioid receptor agonist-1

    CAS:
    K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.
    Fórmula:C22H29Cl2N3O3
    Peso molecular:454.39

    Ref: TM-T88205