CAS 18698-97-0

Ácido 2-bromofenilacético

Descripción:

Ácido 2-bromofenilacético es un compuesto orgánico caracterizado por su estructura aromática y la presencia de un átomo de bromo y un grupo funcional ácido carboxílico. Presenta un átomo de bromo unido a la segunda posición de un anillo fenilo, que está conectado a un grupo de ácido acético. Este compuesto típicamente aparece como un sólido blanco a blanco sucio y es soluble en disolventes orgánicos, con solubilidad limitada en agua debido a su componente aromático hidrofóbico. La presencia del sustituyente bromo puede influir en su reactividad, haciéndolo útil en diversas síntesis químicas y aplicaciones, incluyendo productos farmacéuticos y agroquímicos. Ácido 2-bromofenilacético puede participar en varias reacciones químicas, como sustituciones nucleofílicas y reacciones de acoplamiento, gracias a sus grupos funcionales. Además, puede exhibir actividad biológica, que puede ser explorada en química medicinal. Se deben consultar los datos de seguridad para el manejo y almacenamiento, como con cualquier sustancia química, para asegurar que se tomen las precauciones adecuadas.

Fórmula: C₈H₇BrO₂

InChI: InChI=1/C8H7BrO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)/p-1

Clave InChI: InChIKey=DWXSYDKEWORWBT-UHFFFAOYSA-N

SMILES: c1ccc(c(c1)CC(=O)[O-])Br

Sinónimos:

• (2-Bromophenyl)Acetate
• -Rarechem Al Bo 0109
• 2-(2-Bromophenyl)acetic acid
• 2-Bromobenzeneacetic acid
• 2-Bromophenylacetic acid, 98+%
• Acetic acid, (o-bromophenyl)-
• Benzeneacetic acid, 2-bromo-
• Labotest-Bb Lt00454446
• O-Bromophenylacetic Acid
• Timtec-Bb Sbb006626

2-Bromophenylacetic Acid

CAS: 18698-97-0

Fórmula: C₈H₇BrO₂

Pureza: >98.0%(GC)(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 215.05

Ref: 3B-B1957

2-Bromophenylacetic acid, 98+%

CAS: 18698-97-0

Employed as a pharmaceutical intermediate. It is also used in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code

Fórmula: C₈H₆BrO₂

Pureza: 98+%

Forma y color: White to pale cream, Crystalline powder or powder or crystals

Peso molecular: 214.04

Ref: 02-A16900

2-(2-Bromophenyl)acetic acid

CAS: 18698-97-0

Fórmula: C₈H₇BrO₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 215.0440

Ref: IN-DA00336R

2-Bromophenylacetic acid

CAS: 18698-97-0

Fórmula: C₈H₇BrO₂

Peso molecular: 215.05

Ref: 7W-GK0619

2-Bromophenylacetic acid

CAS: 18698-97-0

2-Bromophenylacetic acid

Fórmula: C₈H₇BrO₂

Pureza: 98%

Forma y color: white solid

Peso molecular: 215.04g/mol

Ref: 54-OR11296

2-Bromophenylacetic acid

CAS: 18698-97-0

2-Bromophenylacetic acid is a potent inhibitor of the human enzyme COX-2. It has been shown to have anticancer activity, which may be due to its ability to inhibit cellular proliferation and induce apoptosis in cancer cells. This compound has been tested in a variety of experimental models, including chromatographic assays and striatal membrane preparations, with promising results. 2-Bromophenylacetic acid also has potent inhibitory activity on the human enzyme COX-2 and can be used as a dietary supplement for anticancer therapy.
COX-2 inhibitors are usually administered as ethyl esters or solutes in order to prevent degradation by esterases or glucuronidases. The 2-bromophenyl group is electron donating and this may increase the reactivity of the carbon adjacent to it and lead to an acylation reaction with nucleophilic groups such as thiols or amines.

Fórmula: C₈H₇BrO₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 215.04 g/mol

Ref: 3D-FB16015

2-Bromophenylacetic acid

CAS: 18698-97-0

Fórmula: C₈H₇BrO₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 215.046

Ref: 10-F001133

2-Bromophenylacetic Acid

Producto controlado

CAS: 18698-97-0

Applications 2-Bromophenylacetic Acid is used as the starting material in the synthesis of 2,3,3a,12b-Tetradehydro Asenapine (T291630); a degredation product of Asenapine (A788000) which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist structurally related to Mianserin (M341500, HCl). Also used as an antipsychotic.
References Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989); Schotte, A., et al.: Brain Res., 631, 191 (1993); Andree, B., et al.: Psychopharmacology, 131, 339 (1997); Richelson, E., et al.: Life Sci., 68, 29 (2000)

Fórmula: C₈H₇BrO₂

Forma y color: Neat

Peso molecular: 215.04

Ref: TR-B687905