CAS 1879-72-7

(11β,16α)-9-Fluoro-11,17-dihidroxi-16-metil-21-(1-oxo-3-fenilpropoxi)pregna-1,4-dieno-3,20-diona

Descripción:

La sustancia química conocida como "(11β,16α)-9-Fluoro-11,17-dihidroxi-16-metil-21-(1-oxo-3-fenilpropoxi)pregna-1,4-dieno-3,20-diona," con el número CAS 1879-72-7, es un corticosteroide sintético. Exhibe propiedades antiinflamatorias e inmunosupresoras, lo que la hace útil en diversas aplicaciones terapéuticas, particularmente en el tratamiento de condiciones como el asma, las alergias y los trastornos autoinmunes. La estructura de este compuesto presenta un átomo de flúor, grupos hidroxilo y una cadena lateral de fenilpropóxido, que contribuyen a su actividad biológica y farmacocinética. La presencia del esqueleto esteroide pregnano es característica de los corticosteroides, que se derivan del colesterol. La estereoequilibrio específico de este compuesto, indicado por la nomenclatura, juega un papel crucial en su interacción con los receptores de glucocorticoides, influyendo en su eficacia y potencia. Al igual que muchos corticosteroides, también puede tener efectos secundarios, incluidos impactos potenciales en el metabolismo y la función inmunológica, lo que requiere una cuidadosa consideración en el uso clínico.

Fórmula: C₃₁H₃₇FO₆

InChI: InChI=1/C31H37FO6/c1-19-15-24-23-11-10-21-16-22(33)13-14-28(21,2)30(23,32)25(34)17-29(24,3)31(19,37)26(35)18-38-27(36)12-9-20-7-5-4-6-8-20/h4-8,13-14,16,19,23-25,34,37H,9-12,15,17-18H2,1-3H3/t19-,23+,24+,25+,28+,29+,30+,31+/m1/s1

Clave InChI: InChIKey=CTKMBLPPDDQOSU-JPYVRCQISA-N

SMILES: F[C@@]12[C@]([C@]3([C@@](C)([C@](C(COC(CCC4=CC=CC=C4)=O)=O)(O)[C@H](C)C3)C[C@@H]1O)[H])(CCC=5[C@]2(C)C=CC(=O)C5)[H]

Sinónimos:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 3-Phenylpropanoate
• Dexamethasone 21-hydrocinnamate
• Dexamethasone 21-phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-hydrocinnamate
• Dexamethasone 21-(3-phenylpropionate)
• (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione
• Dexamethasone Phenylpropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(1-oxo-3-phenylpropoxy)-, (11.beta.,16.alpha.)-
• [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 3-phenylpropanoate
• 9-Fluoro-11β,17-dihydroxy-16α-methyl-21-(1-oxo-3-phenylpropoxy)pregna-1,4-diene-3,20-dione

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Pureza: 95%

Peso molecular: 524.6203

Ref: IN-DA002GK5

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Forma y color: White To Off-White Solid

Peso molecular: 524.63

Ref: 4Z-D-3629

Dexamethasone Phenylpropionate

Producto controlado

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Forma y color: Neat

Peso molecular: 524.62

Ref: TR-D222830

Dexamethasone Phenylpropionate

CAS: 1879-72-7

Fórmula: C₃₁H₃₇FO₆

Peso molecular: 524.63

Ref: ST-EA-CP-D17070

Dexamethasone 21-(3-phenylpropionate)

CAS: 1879-72-7

Dexamethasone 21-(3-phenylpropionate) is a corticosteroid that is used for the treatment of a variety of inflammatory skin conditions. Dexamethasone 21-(3-phenylpropionate) has been shown to be effective in the treatment of cutaneous lesions in mice and rabbits. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit cytokine production. Dexamethasone 21-(3-phenylpropionate) is not metabolized by liver enzymes and has a long half life, making it more predictable than prednisolone. This medication should not be used during pregnancy or if you are trying to become pregnant, as it may cause abortion or premature birth. It should also not be used by women who are breastfeeding, as it can pass through breast milk and affect the baby.

Fórmula: C₃₁H₃₇FO₆

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 524.62 g/mol

Ref: 3D-FD31959