CAS 189028-95-3

(4S)-3-[(5S)-5-(4-fluorofenil)-5-hidroxi-1-oxopentil]-4-fenil-2-oxazolidinona

Descripción:

La sustancia química conocida como (4S)-3-[(5S)-5-(4-fluorofenil)-5-hidroxi-1-oxopentil]-4-fenil-2-oxazolidinona, con el número CAS 189028-95-3, se caracteriza por su estructura central de oxazolidinona, que es un compuesto heterocíclico de cinco miembros que contiene tanto nitrógeno como oxígeno. Este compuesto presenta un centro quiral en la posición 4 del anillo de oxazolidinona, lo que contribuye a su estereoquímica y potencial actividad biológica. La presencia de un grupo 4-fluorofenilo y un moiety de hidroxi cetona sugiere que puede exhibir interacciones significativas con objetivos biológicos, posiblemente influyendo en sus propiedades farmacológicas. La estructura molecular del compuesto indica potencial para aplicaciones en química medicinal, particularmente en el desarrollo de antibióticos u otros agentes terapéuticos. Su solubilidad, estabilidad y reactividad dependerían de los grupos funcionales específicos y su disposición, lo que puede afectar su comportamiento en sistemas biológicos. En general, este compuesto representa una clase de moléculas que pueden tener importantes implicaciones en el descubrimiento y desarrollo de fármacos.

Fórmula: C₂₀H₂₀FNO₄

InChI: InChI=1S/C20H20FNO4/c21-16-11-9-15(10-12-16)18(23)7-4-8-19(24)22-17(13-26-20(22)25)14-5-2-1-3-6-14/h1-3,5-6,9-12,17-18,23H,4,7-8,13H2/t17-,18+/m1/s1

Clave InChI: InChIKey=AVAZNWOHQJYCEL-MSOLQXFVSA-N

SMILES: C(CCC[C@H](O)C1=CC=C(F)C=C1)(=O)N2[C@H](COC2=O)C3=CC=CC=C3

Sinónimos:

• (4S)-3-[(5R)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl]-4-pheny-1,3-oxzolidin-2-One
• (4S)-3-[(5S)-5-(4-Fluoro phenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-2-oxazolidinone
• (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one
• (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one
• (S)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• 2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-
• 2-Oxazolidinone, 3-[5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, [S-(R*,R*)]-
• 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one
• 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-,(4S)-2-Oxazolidinone
• 3-[5-(4-Fluoro-Phenyl)-5-Hydroxy-Pentanoyl]-5-Phenyl-Oxazolidin-2-One

2-Oxazolidinone, 3-[(5S)-5-(4-fluorophenyl)-5-hydroxy-1-oxopentyl]-4-phenyl-, (4S)-

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 357.3755

Ref: IN-DA002HQD

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-Hydroxypentanoyl)-4-Phenyloxazolidin-2-One

Pureza: 99%

Peso molecular: 357.38g/mol

Ref: 54-PC109163

Ezetimibe Impurity 45

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Forma y color: White To Off-White Solid

Peso molecular: 357.38

Ref: 4Z-E-0652

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 357.3810119628906

Ref: 10-F237771

3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one

Producto controlado

CAS: 189028-95-3

Applications 3-[(5S)-(4-Fluorophenyl)-5-hydroxypentanoyl]-(4S)-phenyl-1,3-oxazolidin-2-one is an intermediate of Ezetimibe (E975000, E975002), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.
References Singh, A., et. al.: J. Molecular Catal. B., 85, 99 (2013); van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)

Fórmula: C₂₀H₂₀FNO₄

Forma y color: Neat

Peso molecular: 357.38

Ref: TR-F595465

Ezetimibe Impurity 16

CAS: 189028-95-3

Fórmula: C₂₀H₂₀FNO₄

Peso molecular: 357.38

Ref: ST-EA-CP-E6041

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is an enzyme inhibitor that interrupts the biosynthesis of glucose by inhibiting the activity of the enzyme glucose dehydrogenase. This drug has been shown to be efficacious against a number of strains, including E. coli and S. typhimurium, but not other bacteria such as escherichia or mycobacteria. (S)-3((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is used in medicines to treat cardiovascular diseases. It has been shown to inhibit the production of dinucleotide phosphate, which is essential for the synthesis of nucleic acids and energy production in cells. The reaction system is circularly closed by this molecule.br>br>

Pureza: Min. 95%

Ref: 3D-FF57617

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one

CAS: 189028-95-3

(S)-3-((S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one is a useful organic compound for research related to life sciences. The catalog number is T66207 and the CAS number is 189028-95-3.

Fórmula: C₂₀H₂₀FNO₄

Forma y color: Solid

Peso molecular: 357.381

Ref: TM-T66207