CAS 19210-12-9
:Harpagósido
Descripción:
Harpagósido es un glucósido iridoide que se encuentra de forma natural principalmente en las raíces de la planta Harpagophytum procumbens, comúnmente conocida como garra del diablo. Se caracteriza por su fórmula molecular, que incluye átomos de carbono, hidrógeno y oxígeno, reflejando su estructura glucosídica. Harpagósido es conocido por sus potenciales propiedades antiinflamatorias y analgésicas, lo que lo hace de interés en la medicina herbal y los suplementos dietéticos, particularmente para condiciones como la artritis y el dolor articular. El compuesto exhibe un sabor amargo y a menudo se extrae para su uso en diversas formulaciones. En términos de solubilidad, Harpagósido es generalmente soluble en agua y solventes orgánicos, lo que facilita su extracción e incorporación en varios productos. Sus efectos farmacológicos se atribuyen a su capacidad para modular las vías inflamatorias e influir en la percepción del dolor. Al igual que muchos compuestos naturales, la eficacia y seguridad de Harpagósido pueden variar según la dosis y la respuesta individual, lo que requiere más investigación para comprender completamente su potencial terapéutico y mecanismos de acción.
Fórmula:C24H30O11
InChI:InChI=1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1
Clave InChI:InChIKey=KVRQGMOSZKPBNS-FMHLWDFHSA-N
SMILES:O[C@@]12[C@@]([C@](OC(/C=C/C3=CC=CC=C3)=O)(C)C[C@H]1O)([C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC=C2)[H]
Sinónimos:- (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
- (1S,4aS,5R,7S,7aS)-1-(beta-D-glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl (2E)-3-phenylprop-2-enoate
- (1S-(1alpha,4aalpha,5alpha,7alpha(E),7aalpha))-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-((allyl-1-oxo-3-phenyl)oxy)cyclopenta(c)pyran-1-yl-beta-D-glucopyranoside
- 1-(Hexopyranosyloxy)-4A,5-Dihydroxy-7-Methyl-1,4A,5,6,7,7A-Hexahydrocyclopenta[C]Pyran-7-Yl 3-Phenylprop-2-Enoate
- E-Harpagoside
- Hapagoside
- Harpagoside
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]cyclopenta[c]pyran-1-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(1-oxo-3-phenyl-2-propenyl)oxy]cyclopenta[c]pyran-1-yl, [1S-[1α,4aα,5α,7α(E),7aα]]-
- β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]cyclopenta[c]pyran-1-yl
- (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-D-glucopyranoside
- β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl
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Encontrado 16 productos.
Harpagoside
CAS:Harpagoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C24H30O11Pureza:(HPLC) ≥98%Forma y color:PowderPeso molecular:494.49Harpagoside
CAS:Fórmula:C24H30O11Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:494.49Harpagoside
CAS:Harpagoside has anti-inflammatory effects, it blocks lipopolysaccharide (LPS)-induced bone loss in an inflammatory osteoporosis model, and it does not prevent ovariectomy-mediated bone erosion in a postmenopausal osteoporosis model, it may lead to a partial prevention of obesity-induced atherosclerosis by attenuating inflammatory responses. Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-κB activation. Harpagoside exerts neuroprotection effect and ameliorates learning and memory deficit appears to be associated, at least in part, with up-regulation of brain-derived neurotrophic factor (BDNF) content as well as activating its downstream signaling pathways, e.g., MAPK/PI3K pathways.Fórmula:C24H30O11Pureza:95%~99%Peso molecular:494.493Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Fórmula:C24H30O11Pureza:99.71% - ≥95%Forma y color:White To Off-White PowderPeso molecular:494.49Harpagoside
CAS:Natural glycosideFórmula:C24H30O11Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:494.5Harpagoside
CAS:<p>Applications Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.<br>References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);<br></p>Fórmula:C24H30O11Forma y color:NeatPeso molecular:494.49Harpagoside
CAS:<p>Harpagoside is a bioactive compound, which is an iridoid glycoside derived from the root of the plant Harpagophytum procumbens, commonly known as Devil’s Claw. This compound is predominantly sourced from Southern Africa, where the plant is native to semi-arid regions and has been traditionally used in herbal medicine.</p>Fórmula:C24H30O11Pureza:Min. 95%Forma y color:PowderPeso molecular:494.5 g/molHarpagoside-D5
CAS:Producto controlado<p>Applications Harpagoside-D5 is an isotope labelled analog of Harpagoside (H105275). Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.<br>References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);<br></p>Fórmula:C24D5H25O11Forma y color:NeatPeso molecular:499.519
