CAS: 192185-72-1 - Tipifarnib

Fórmula: C₂₇H₂₂Cl₂N₄O

InChI: InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1

Clave InChI: InChIKey=PLHJCIYEEKOWNM-HHHXNRCGSA-N

SMILES: O=C1C=C(C=2C=CC=C(Cl)C2)C=3C=C(C=CC3N1C)C(N)(C4=CC=C(Cl)C=C4)C5=CN=CN5C

Sinónimos:

• (R)-(+)-R 115777
• (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
• 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
• 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
• 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
• Tipifarnib Zarnestra
• Zarnestra

2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-

CAS: 192185-72-1

• Fórmula: C₂₇H₂₂Cl₂N₄O
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 489.3958

Tipifarnib

CAS: 192185-72-1

Tipifarnib

CAS: 192185-72-1

• Fórmula: H₂
• Pureza: >98%
• Forma y color: white solid
• Peso molecular: 489.40g/mol

Tipifarnib

CAS: 192185-72-1

Tipifarnib (IND 58359), a quinolinone, inhibits farnesyl transferase, blocks Ras activation, arrests cell growth, and …

• Fórmula: C₂₇H₂₂Cl₂N₄O
• Pureza: 97.1% - 99.22%
• Forma y color: Off-White To Pale Beige Solid
• Peso molecular: 489.4

Tipifarnib

CAS: 192185-72-1

Applications A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation …

• Fórmula: C₂₇H₂₂Cl₂N₄O
• Forma y color: Neat
• Peso molecular: 489.40

Tipifarnib

CAS: 192185-72-1

Tipifarnib is a peptide substrate that inhibits the enzyme DNA methyltransferase, which is responsible for …

• Fórmula: C₂₇H₂₂Cl₂N₄O
• Pureza: Min. 95%
• Peso molecular: 489.4 g/mol