CAS 192725-17-0
:Lopinavir
Descripción:
Lopinavir es un medicamento antirretroviral utilizado principalmente en el tratamiento del VIH/SIDA. Pertenece a la clase de inhibidores de la proteasa y a menudo se combina con ritonavir para mejorar su eficacia y biodisponibilidad. La fórmula química de Lopinavir es C37H48N4O5, y tiene un peso molecular de aproximadamente 628.88 g/mol. Lopinavir se caracteriza por su estructura compleja, que incluye múltiples anillos y grupos funcionales que contribuyen a su actividad farmacológica. Se administra típicamente por vía oral en forma de tabletas o solución líquida. La sustancia es conocida por su capacidad para inhibir la enzima proteasa del VIH, evitando así la replicación viral. Lopinavir generalmente es bien tolerado, pero puede tener efectos secundarios, incluidos trastornos gastrointestinales y posibles impactos en el metabolismo de lípidos. Debido a su papel en el tratamiento del VIH, Lopinavir a menudo forma parte de regímenes de terapia combinada, que pueden incluir otros agentes antirretrovirales para mejorar los resultados del tratamiento y reducir el riesgo de resistencia.
Fórmula:C37H48N4O5
InChI:InChI=1/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
Clave InChI:InChIKey=KJHKTHWMRKYKJE-SUGCFTRWSA-N
SMILES:[C@@H](C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)([C@@H](C)C)N4C(=O)NCCC4
Sinónimos:- A 157378.0
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- 1(2H)-Pyrimidineacetamide, N-[(1S,3S,4S)-4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, (αS)-
- (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- 1(2H)-Pyrimidineacetamide, N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-, [1S-[1R*(R*),3R*,4R*]]-
- ABT 378
- ABT-378
- UNII-2494G1JF75
- Kaletra
- (S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- (1S-(1R*(R*),3R*,4R*))-N-(4-(((2,6-Dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
- (2S)-N-[(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide
- 1(2H)-Pyrimidineacetamide, N-((1S,3S,4S)-4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahyrdo-alpha-1-methylethyl)-2-oxo-, (alphaS)-
- (alphaS)-Tetrahydro-N-((alphaS)-alpha-((2S,3S)-2-hydroxy-4-phenyl-3-(2-(2,6-xylyloxy)acetamido)butyl)phenethyl)-alpha-isopropyl-2-oxo-1(2H)-pyrimidineacetamide
- LOPINAVIR
- Aluviran
- Koletra
- (2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
- (2s)-n-[(2r,4s,5s)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
- (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
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Encontrado 20 productos.
Lopinavir
CAS:Fórmula:C37H48N4O5Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:628.81LOPINAVIR FOR SYSTEM SUITABILITY CRS
CAS:LOPINAVIR FOR SYSTEM SUITABILITY CRSFórmula:C37H48N4O5Peso molecular:628.8008LOPINAVIR FOR PEAK IDENTIFICATION CRS
CAS:LOPINAVIR FOR PEAK IDENTIFICATION CRSFórmula:C37H48N4O5Peso molecular:628.8008Lopinavir
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFórmula:C37H48N4O5Forma y color:White Off-White PowderPeso molecular:628.36247(2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
CAS:Fórmula:C37H48N4O5Pureza:%Forma y color:SolidPeso molecular:628.8008Ref: IN-DA003RD4
1g158,00€5gA consultar100gA consultar10mg30,00€25mg50,00€50mg50,00€100mg65,00€250mg99,00€Lopinavir EP Impurity H
CAS:Fórmula:C29H32N2O4Forma y color:White To Off-White SolidPeso molecular:472.58Lopinavir
CAS:Fórmula:C37H48N4O5Pureza:≥ 98.0% (anhydrous basis)Forma y color:White crystalline powderPeso molecular:628.80Lopinavir
CAS:<p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>Fórmula:C37H48N4O5Pureza:98% - 99.62%Forma y color:White Crystalline SolidPeso molecular:628.8Lopinavir
CAS:<p>Stability Hygroscopic<br>Applications A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Fórmula:C37H48N4O5Forma y color:White SolidPeso molecular:628.80Lopinavir
CAS:<p>Anti-viral; HIV protease inhibitor</p>Fórmula:C37H48N4O5Pureza:Min. 97.5 Area-%Forma y color:White Off-White PowderPeso molecular:628.8 g/molLopinavir - Bio-X ™
CAS:<p>Chemically derived from ritonavir, Lopinavir belongs to the amphetamines. Lopinavir is clinically used in the prevention and treatment of HIV infections as it acts as HIV-1 protease inhibitor. In 2020, lopinavir was tested to treat COVID-19 patients and although it led to a higher rate of gastrointestinal side effects, the Lopinavir-treated group had a lower incidence of severe complications. Overall it was deemed not to work as a treatment.</p>Fórmula:C37H48N4O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:628.8 g/molN5-Des[(2,6-dimethylphenoxy)acetyl] N5-Formal Lopinavir
CAS:Producto controladoFórmula:C28H38N4O4Forma y color:NeatPeso molecular:494.63Ref: 10-F079428
Producto descatalogado
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