CAS 19309-14-9

Cardamonina

Descripción:

Cardamonina es un compuesto que se encuentra de forma natural clasificado como un chalcona, derivado principalmente de las semillas de la planta Elettaria cardamomum, comúnmente conocida como cardamomo. Se caracteriza por su apariencia cristalina amarilla y tiene una fórmula molecular que refleja su estructura compleja. Cardamonina exhibe diversas actividades biológicas, incluyendo propiedades antiinflamatorias, antioxidantes y antimicrobianas, lo que lo hace de interés en la investigación farmacológica. Su mecanismo de acción a menudo implica la modulación de vías de señalización, que pueden influir en la proliferación celular y la apoptosis. Además, Cardamonina ha sido estudiado por sus posibles efectos terapéuticos en condiciones como el cáncer y trastornos metabólicos. El compuesto es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua, lo que puede afectar su biodisponibilidad. En general, Cardamonina representa un área significativa de interés en la química de productos naturales y la investigación medicinal debido a sus diversas actividades biológicas y posibles beneficios para la salud.

Fórmula: C₁₆H₁₄O₄

InChI: InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

Clave InChI: InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N

SMILES: C(/C=C/C1=CC=CC=C1)(=O)C2=C(OC)C=C(O)C=C2O

Sinónimos:

• (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
• (2E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
• (E)-1-(2,4-Dihydroxy-6-Methoxy-Phenyl)-3-Phenyl-Propenone
• (E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-, (E)-
• Alpinetin chalcone
• Cardamomin
• Chalcone, 2', 4'-dihydroxy-6'-methoxy-
• Chalcone, 2′,4′-dihydroxy-6′-methoxy-
• Cardamonin

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera.

Fórmula: C₁₆H₁₄O₄

Pureza: 99.07% - 99.84%

Forma y color: Solid

Peso molecular: 270.28

Ref: TM-T2994

Cardamonin

CAS: 19309-14-9

Fórmula: C₁₆H₁₄O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 270.2800

Ref: IN-DA00AOR0

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

CAS: 19309-14-9

(E)-1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-Phenylprop-2-En-1-One

Pureza: 99%

Peso molecular: 270.28g/mol

Ref: 54-OR1008324

(E)-Cardamonin

CAS: 19309-14-9

(E)-Cardamonin

Pureza: ≥98%

Peso molecular: 270.28g/mol

Ref: 54-BUP11154

Cardamonin

CAS: 19309-14-9

Cardamonin is a naturally occurring chalcone with strong anti-inflammatory , anticancer, anti-melanogenesis, and vascular activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor. It ameliorates insulin resistance induced by high insulin and high glucose through the mTOR and signal pathway. It also may be a potential whitening agent for use in cosmetics and in the medical treatment of hyperpigmentation disorders.

Fórmula: C₁₆H₁₄O₄

Pureza: 95%~99%

Peso molecular: 270.284

Ref: BP-BP0315

Cardamonin

CAS: 19309-14-9

Fórmula: C₁₆H₁₄O₄

Pureza: ≥ 98.0%

Forma y color: Yellow powder

Peso molecular: 270.28

Ref: 7W-GK9563

Cardamomin

CAS: 19309-14-9

Ketone phenol

Fórmula: C₁₆H₁₄O₄

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 270.29

Ref: 5G-80379

Cardamonin

CAS: 19309-14-9

Cardamonin is a natural chalcone, which is a type of aromatic ketone and an unsaturated polyphenolic compound. It is primarily sourced from various plants, particularly from the seeds of Alpinia katsumadai, a member of the Zingiberaceae family. Its mode of action involves modulation of multiple cellular pathways, including inhibition of NF-κB activation, which plays a critical role in inflammatory responses and cancer cell proliferation. Additionally, cardamonin has been shown to interfere with other signaling pathways like MAPK and PI3K/Akt, which are key in regulating cell growth and survival.

Fórmula: C₁₆H₁₄O₄

Pureza: Min. 95%

Forma y color: Yellow Powder

Peso molecular: 270.28 g/mol

Ref: 3D-FC66017

Cardamonin

CAS: 19309-14-9

Applications Cardamonin maintains inhibitory effects of cardamonin on thromboxane A2-induced scratching response in mice. Also inhibits angiotensin II-induced vascular smooth muscle cell proliferation.
References Park, M. et al.: Pharm. Biochem. Behav., 126, 131 (2014); Shen, Y. et al.: J. Nat. Med., 68, 623 (2014);

Fórmula: C₁₆H₁₄O₄

Forma y color: Off White Solid

Peso molecular: 270.28

Ref: TR-C183380