CAS 1953-04-4

Hidrobromuro de galantamina

Descripción:

Hidrobromuro de galantamina es un inhibidor reversible de la enzima acetilcolinesterasa, utilizado principalmente en el tratamiento de la enfermedad de Alzheimer leve a moderada y otros trastornos cognitivos. Es un compuesto de amonio cuaternario derivado de la planta de campanilla y exhibe un mecanismo de acción dual al mejorar la función colinérgica y modular los receptores nicotínicos. La sustancia aparece como un polvo cristalino blanco a blanco amarillento, es soluble en agua y tiene una fórmula molecular que refleja su estructura compleja. Hidrobromuro de galantamina se administra típicamente por vía oral y es conocido por su capacidad para mejorar la función cognitiva y la memoria en los pacientes. Su farmacocinética implica procesos de absorción, distribución, metabolismo y excreción que están influenciados por factores como la edad y la función hepática. Los efectos secundarios comunes pueden incluir náuseas, vómitos y diarrea, que generalmente son leves. Al igual que con cualquier medicamento, es esencial usar Hidrobromuro de galantamina bajo supervisión médica para monitorear la eficacia y las posibles reacciones adversas.

Fórmula: C₁₇H₂₂BrNO₃

InChI: InChI=1/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/p+1/t12-,14-,17-/m0/s1

Clave InChI: InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N

SMILES: O(C)C1=C2C=3[C@]4([C@@](O2)(C[C@@H](O)C=C4)[H])CCN(C)CC3C=C1.Br

Sinónimos:

• (4aS,6R,8aS)-6-hydroxy-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium
• 5A,6,7,8,8A,12B-Hexahydrogalanthamine Hydrobromide (1:1)
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide (1:1), (4aS,6R,8aS)-
• 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, hydrobromide, (4aS,6R,8aS)-
• Galantamine Hbr
• Galantamine Hydrobromide
• Galanthamine HBr
• Galanthamine Hydrobromide (1:1)
• Galanthamine hydrogen bromide
• Jilkon hydrobromide
• Lycoremine hydrobromide
• Nivalin
• Nivaline
• Nivaline (pharmaceutical)
• Razadyne
• Reminyl
• Tamilin
• Galanthamine, hydrobromide
• GALANTHAMINE HYDROBROMIDUM
• Galanthamine Hydrobromide Injection
• Hydrobromic acid·galanthamine
• 4A,5,9,10,11,12-HEXAHYDRO-3-METHOXY-11-METHYL-6H-BENZOFURO[3A,3,2-EF][2]BENZAZEPIN-6-OL HYDROBROMIDE
• NIVALIN, HBR
• (-)-Galanthaminium bromide
• GALANTHAMIDE HYDROBROMIDE
• galanthamine hydrobromide from lycoris sp.

Galantamine Hydrobromide

CAS: 1953-04-4, 357-70-0

Fórmula: C₁₇H₂₁NO₃·HBr

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 368.27

Ref: 3B-G0293

Galanthamine hydrobromide

CAS: 1953-04-4

Centrally active and long-acting acetylcholinesterase inhibitor

Fórmula: C₁₇H₂₁NO₃•HBr

Peso molecular: 368.27

Ref: 02-J62482

Galantamine hydrobromide impurity standard

CAS: 1668-85-5, 1953-04-4, 199014-26-1, 60755-80-8

Galantamine hydrobromide impurity standard

Forma y color: White Powder

Ref: 47-1214

Galantamine hydrobromide

CAS: 1953-04-4

Galantamine hydrobromide

Fórmula: C₁₇H₂₁NO₃

Pureza: 77.4%

Forma y color: White

Peso molecular: 287.15214

Ref: 47-1111

GALANTAMINE HYDROBROMIDE CRS

CAS: 1953-04-4

GALANTAMINE HYDROBROMIDE CRS

Fórmula: C₁₇H₂₂BrNO₃

Peso molecular: 368.2655

Ref: 41-Y0001279

GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS

CAS: 1953-04-4

GALANTAMINE NATURAL FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₇H₂₂BrNO₃

Forma y color: Crystalline Powder. White. Amorphous.

Peso molecular: 368.2655

Ref: 41-Y0001190

GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS

CAS: 1953-04-4

GALANTAMINE SYNTHETIC FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₇H₂₂BrNO₃

Peso molecular: 368.2655

Ref: 41-Y0001191

Galantamine Hydrobromide

CAS: 1953-04-4, 69353-21-5

Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi

Fórmula: C₁₇H₂₁NO₃·BrH

Forma y color: White Powder

Peso molecular: 367.07831

Ref: 45-1287755

(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide

CAS: 1953-04-4

Fórmula: C₁₇H₂₂BrNO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 368.2655

Ref: IN-DA0034YM

Galanthamine hydrobromide

CAS: 1953-04-4

Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal

Fórmula: C₁₇H₂₁NO₃·HBr

Pureza: 98% - 99.49%

Forma y color: White To Off-White Powder

Peso molecular: 368.27

Ref: TM-T0086

Galantamine HBr

CAS: 1953-04-4

Fórmula: C₁₇H₂₁NO₃·HBr

Forma y color: White To Off-White Solid

Peso molecular: 287.36 80.91

Ref: 4Z-G-016

Galantamine Hydrobromide

CAS: 1953-04-4

Galantamine Hydrobromide

Pureza: 98%

Peso molecular: 368.27g/mol

Ref: 54-OR1027829

Galanthamine hydrobromide

CAS: 1953-04-4

Fórmula: C₁₇H₂₁NO₃HBr

Pureza: ≥ 98.0%

Forma y color: White powder

Peso molecular: 368.27

Ref: 7W-GP2704

Galanthamine hydrobromide

CAS: 1953-04-4

Galanthamine hydrobromide

Pureza: ≥98%

Peso molecular: 368.27g/mol

Ref: 54-BUP11938

Galantamine hydrobromide

Producto controlado

CAS: 1953-04-4

Fórmula: C₁₇H₂₁NO₃·BrH

Forma y color: Neat

Peso molecular: 368.27

Ref: 04-C13997200

Galanthamine hydrobromide

CAS: 1953-04-4

Fórmula: C₁₇H₂₂BrNO₃

Pureza: 95%~99%

Peso molecular: 368.271

Ref: BP-BP0607

Galantamine Hydrobromide

Producto controlado

CAS: 1953-04-4

Fórmula: C₁₇H₂₁NO₃·BrH

Forma y color: Neat

Peso molecular: 368.27

Ref: 86-MM1256.00

Galanthamine hydrobromide

CAS: 1953-04-4

Natural alkaloid

Fórmula: C₁₇H₂₁NO₃HBr

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 368.27

Ref: 5G-89666

Galanthamine Hydrobromide

Producto controlado

CAS: 1953-04-4

Applications A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Friess, S.L., et al.: Toxicol. Appl. Pharmacol., 3, 347 (1961), Bickel, U., et al.: Clin. Pharmacol. Ther., 50, 420 (1991), Harvey, A.L., et al.: Pharmacol. Ther., 68, 113 (1995),

Fórmula: C₁₇H₂₁NO₃·BrH

Forma y color: White To Off-White

Peso molecular: 368.27

Ref: TR-G188500

Galanthamine hydrobromide

Producto controlado

CAS: 1953-04-4

A reversible and competitive inhibitor of acetylcholinesterase (AChE) that is approved for the treatment of Alzheimer’s disease. It is also an allosteric modulator of nicotinic acetylcholine receptors (nAChR). Activation of nAChR along with upregulation of anti-apoptotic protein Bcl-2 prevents apoptosis and therefore provides neuroprotection.

Fórmula: C₁₇H₂₁NO₃·HBr

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 368.27 g/mol

Ref: 3D-FH15701

Galanthamine-O-methyl-d3 Hydrobromide

Producto controlado

CAS: 1953-04-4

Fórmula: C₁₇D₃H₁₈NO₃·HBr

Forma y color: Neat

Peso molecular: 371.284

Ref: TR-G188504

9-Bromo-7-methoxy-1,2,3,4-tetrahydrobenzofuro[4,3-cd]azepine Hydrobromide

Producto controlado

CAS: 1953-04-4

Fórmula: C₁₂H₁₂BrNO₂·HBr

Forma y color: Neat

Peso molecular: 363.05

Ref: TR-B188550

Galantamine Hydrobromide extrapure, 98%

CAS: 1953-04-4

Fórmula: C₁₇H₂₁NO₃·HBr

Pureza: min. 98%

Forma y color: White to off - white, Hygroscopic crystalline powder

Peso molecular: 368.27

Ref: SR-83055