CAS 1957203-02-9

CDK7-IN-1

CAS: 1957203-02-9

CDK7-IN-1, analog of YKL-5-124, inhibits cdk7 with IC50 < 100 nM.

Fórmula: C₂₈H₃₅N₇O₃

Forma y color: Solid

Peso molecular: 517.634

Ref: TM-T39372

CDK7-IN-1

CAS: 1957203-02-9

CDK7-IN-1 is a potent and selective inhibitor of the human cyclin-dependent kinase 7 (CDK7) protein, which is involved in cell cycle regulation. This analog has shown anticancer activity in Chinese hamster ovary cells and has been identified as a potential anticancer drug candidate. CDK7-IN-1 is a potent inhibitor of tumor growth and induces apoptosis in cancer cells. It has been shown to be effective against a variety of cancers, including breast, lung, and ovarian cancer. This inhibitor also exhibits high selectivity for CDK7 over other kinases, making it an attractive target for cancer therapy. Additionally, CDK7-IN-1 has low toxicity and is excreted primarily in urine, making it a promising candidate for further development as an anticancer agent.

Fórmula: C₂₈H₃₉N₇O₃

Pureza: Min. 95%

Peso molecular: 521.7 g/mol

Ref: 3D-HDD20302