CAS 199739-10-1

Palmitato de Paliperidona

Descripción:

Palmitato de Paliperidona es un medicamento antipsicótico atípico utilizado principalmente en el tratamiento de la esquizofrenia y el trastorno esquizoafectivo. Es una formulación de liberación prolongada de paliperidona, que es el metabolito activo de risperidona. Este compuesto se caracteriza por sus propiedades de acción prolongada, lo que permite una dosificación menos frecuente en comparación con los antipsicóticos orales. Químicamente, Palmitato de Paliperidona es un éster de palmitato de paliperidona, que mejora su lipofilia y facilita la liberación sostenida en el torrente sanguíneo. La sustancia se administra típicamente mediante inyección intramuscular, proporcionando efectos terapéuticos durante un período prolongado, a menudo hasta un mes. Su mecanismo de acción implica el antagonismo de los receptores de dopamina D2 y de serotonina 5-HT2A, contribuyendo a su eficacia en el manejo de síntomas psicóticos. Los efectos secundarios comunes pueden incluir aumento de peso, sedación y cambios metabólicos. Al igual que con otros antipsicóticos, es esencial un monitoreo cuidadoso para gestionar posibles efectos adversos y garantizar la seguridad del paciente. En general, Palmitato de Paliperidona representa un avance significativo en el manejo farmacológico de condiciones psiquiátricas crónicas.

Fórmula: C₃₉H₅₇FN₄O₄

InChI: InChI=1S/C39H57FN4O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18-36(45)47-34-17-16-24-44-38(34)41-29(2)32(39(44)46)23-27-43-25-21-30(22-26-43)37-33-20-19-31(40)28-35(33)48-42-37/h19-20,28,30,34H,3-18,21-27H2,1-2H3

Clave InChI: InChIKey=VOMKSBFLAZZBOW-UHFFFAOYSA-N

SMILES: FC=1C=C2C(C(=NO2)C3CCN(CCC=4C(=O)N5C(=NC4C)C(OC(CCCCCCCCCCCCCCC)=O)CCC5)CC3)=CC1

Sinónimos:

• (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidin-9-yl hexadecanoate
• 9-Hydroxyrisperidone palmitate
• Hexadecanoic acid, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido(1,2-a)pyrimidin-9-yl ester
• Invega Sustenna
• Paliperidone Palmitate [USAN]
• Ro 92670
• Ro92670
• Trevicta
• Unii-R8P8Usm8Fr
• Xeplion
• Paliperidone palmitate
• Paliperidone palmitate
• (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)et
• Paliperidone Palmitate Benzisoxazole Impurity
• hyl)-2-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyriMi
• Hexadecanoic acid 3-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]-ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester
• Paliperidone Palmitate USP/EP/BP
• Paliperidone Palmitate-d31
• 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate
• Paliperidone palmitateQ: What is
• Paliperidone palmitate Q: What is the CAS Number of
• Paliperidone palmitate Q: What are the applications of
• din-9-yl hexadecanoate
• Paliperidone Impurity 39 (Paliperidone Palmitate)

Paliperidone Palmitate

CAS: 199739-10-1

Fórmula: C₃₉H₅₇FN₄O₄

Pureza: >98.0%(HPLC)(T)

Peso molecular: 664.91

Ref: 3B-P2967

Paliperidone Palmitate

CAS: 199739-10-1

Paliperidone Palmitate

Fórmula: C₃₉H₅₇FN₄O₄

Pureza: >98.0%

Peso molecular: 664.91

Ref: 54-PC1008641

Paliperidone Palmitate

CAS: 199739-10-1

Fórmula: C₃₉H₅₇FN₄O₄

Forma y color: Off-White Solid

Peso molecular: 664.91

Ref: 4Z-P-664

Paliperidone Palmitate

CAS: 199739-10-1

Forma y color: Neat

Ref: 86-MM3627.00

Paliperidone Palmitate

CAS: 199739-10-1

Paliperidone Palmitate is a long-acting prodrug of paliperidone. Acting as a D2 and 5-HT2A antagonist, it enables sustained drug release via intramuscular depot, utilized in schizophrenia treatment and drug delivery system research.

Fórmula: C₃₉H₅₇FN₄O₄

Pureza: 98%

Forma y color: White Solid

Peso molecular: 664.89

Ref: TM-T19950

Paliperidone Palmitate

CAS: 199739-10-1

Applications Paliperidone Palmitate is a long-acting injectable atypical antipsychotic used in the treatment of schizophrenia.
References Hough, D. et al.: Prog. Neuro-psychophamacol. Biol. Psych., 33, 1022 (2009); Samtani, M.N. et al.: Clin. Pharmacokin., 48, 585 (2009); Nasrallah, H.A. et al.: Neuropsychopharmacology, 35, 2072 (2010);

Fórmula: C₃₉H₅₇FN₄O₄

Forma y color: Neat

Peso molecular: 664.89

Ref: TR-P141020

Paliperidone Palmitate-d31

CAS: 199739-10-1

Fórmula: C₃₉H₂₆FN₄O₄D₃₁

Peso molecular: 696.10

Ref: 4Z-P-6626

Paliperidone palmitate

Producto controlado

CAS: 199739-10-1

Paliperidone palmitate is a drug that is used in the treatment of schizophrenia. It is the most potent and selective atypical antipsychotic agent available. Paliperidone palmitate has shown long-term efficacy and low risk of extrapyramidal symptoms, which are associated with some other antipsychotic agents. The drug has been shown to have minimal effects on prolactin levels, although it can cause an increase in serum prolactin levels when administered with risperidone. Paliperidone palmitate is a prodrug that is metabolized by esterases to its active form, paliperidone. Paliperidone does not bind to plasma proteins and therefore may be more suitable for patients with hepatic impairment.

Fórmula: C₃₉H₅₇FN₄O₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 664.89 g/mol

Ref: 3D-FP26726

Paliperidone Palmitate

CAS: 199739-10-1

Fórmula: C₃₉H₅₇FN₄O₄

Peso molecular: 664.9

Ref: BE-RMCP013030

Paliperidone Palmitate

CAS: 199739-10-1

Fórmula: C₃₉H₅₇FN₄O₄

Peso molecular: 664.91

Ref: ST-EA-CP-P13055