CAS 2001-95-8

Valinomicina

Descripción:

Valinomicina es un antibiótico ionóforo cíclico que se conoce principalmente por su capacidad para transportar selectivamente iones de potasio a través de membranas lipídicas. Está compuesto por un anillo de lactona de 12 miembros formado por la condensación de varios aminoácidos, incluyendo valina, que le da su nombre. Valinomicina exhibe una alta afinidad por los iones K+ debido a su estructura única, que le permite encapsular el ion de manera efectiva, facilitando su movimiento a través de membranas biológicas. Esta propiedad convierte a Valinomicina en una herramienta valiosa en la investigación bioquímica, particularmente en estudios que involucran el transporte de iones y el potencial de membrana. Además, se ha demostrado que Valinomicina exhibe actividad antimicrobiana contra varios microorganismos. Su mecanismo de acción implica interrumpir el equilibrio iónico dentro de las células, lo que lleva a la muerte celular. Valinomicina es soluble en disolventes orgánicos y tiene una solubilidad limitada en agua, lo que influye en su aplicación en entornos de laboratorio. Debido a sus potentes efectos biológicos, se utiliza en varios protocolos experimentales, incluidos estudios sobre canales iónicos y vías de señalización celular.

Fórmula: C₅₄H₉₀N₆O₁₈

InChI: InChI=1/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36?,37-,38-,39-,40+,41+,42+/m0/s1

Sinónimos:

• 1,7,13,19,25,31-Hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone, 3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-
• Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
• Nsc 122023
• Valinomicin
• Valinomicina
• Valinomycine
• valinomicin[qr]
• VALINOMYCIN READY MADE SOLUTION
• aleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l
• CYCLO[-L-VAL-D-HYLVA-D-VAL-L-LAC-]3
• cyclic(d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisov
• 1Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-
• akis(1-methylethyl)-[qr]
• Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid
• VALINOMYCIN 99%
• 3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-triMethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
• VALINOMYCIN >94% PURITY
• Valinomycin,90%
• ValinoMycin, froM StreptoMyces fulvissiMus
• 1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,
• hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
• Valinomycin,Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid
• 14,17,20,23,26,29,32,35-dodecone,12,24,36-trimetyl-3,6,9,15,18,21,27,30,33-non
• antibioticn-329b
• VALINOMYCINRESEARCH GRADE
• -valyl)[qr]
• nsc122023[qr]
• POTASSIUM IONOPHORE I
• Valinomycin,96%
• VALINOMYCIN, STREPTOMYCES FULVISSIMUS
• nsc122023
• Potassium ionophore I,Valinomycin
• VALINOMYCIN
• CYCLO(LAC-VAL-D-HIV-D-VAL-LAC-VAL-D-HIV-D-VAL-)

Valinomycin, 90+%

CAS: 2001-95-8

Potassium-selective ionophoric cyclodepsipeptide; inhibitor of mitochondrial action

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: 90+%

Forma y color: White, Powder or crystals or crystalline powder

Peso molecular: 1111.34

Ref: 02-J62312

Valinomycin

CAS: 2001-95-8

Valinomycin

Pureza: ≥95%

Peso molecular: 1111.32g/mol

Ref: 54-BUP02178

Valinomycin

CAS: 2001-95-8

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: ≥ 95%

Forma y color: White powder

Peso molecular: 1111.34

Ref: 7W-GA5799

Valinomycin

CAS: 2001-95-8

Valinomycin

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: By hplc: 100% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 1,111.32g/mol

Ref: 54-BIV0893

Valinomycin

CAS: 2001-95-8

Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: 95.37% - 97.16%

Forma y color: White Solid

Peso molecular: 1111.32

Ref: TM-TP1072

Valinomycin

Producto controlado

CAS: 2001-95-8

Applications K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. Used as insecticide, nematocide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ivanov, et al.: Biochem. Biophys. Res. Commun., 34, 803 (1969), Duax, et al.: Science, 176, 911 (1972),

Fórmula: C₅₄H₉₀N₆O₁₈

Forma y color: Neat

Peso molecular: 1111.32

Ref: TR-V094370

Valinomycin

CAS: 2001-95-8

Valinomycin is an ionophore antibiotic with action on potassium ion transport across cell membranes and is used for research on ion transport and as an antimicrobial agent.

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: Min. 90 Area-%

Forma y color: White Powder

Peso molecular: 1,111.32 g/mol

Ref: 3D-AV28656

Valinomycin, 95%

CAS: 2001-95-8

Fórmula: C₅₄H₉₀N₆O₁₈

Pureza: min. 95%

Forma y color: White, Crystalline powder, Clear, Colourless

Peso molecular: 1111.3

Ref: SR-40652