CAS 2002-35-9

2'-Desoxi-N6-metiladenosina

Descripción:

2'-Desoxi-N6-metiladenosina (CAS 2002-35-9) es un nucleósido modificado que juega un papel significativo en varios procesos biológicos, particularmente en el contexto de la metilación de ARN y ADN. Es un derivado de la adenosina, donde se añade un grupo metilo al átomo de nitrógeno en la sexta posición de la base de adenina. Esta modificación puede influir en la expresión génica y está involucrada en la regulación de varias funciones celulares. La presencia del azúcar 2′-desoxi ribosa lo distingue de otros nucleósidos, convirtiéndolo en un componente del ADN en lugar de ARN. La metilación de nucleósidos como 2'-Desoxi-N6-metiladenosina es crucial para la regulación epigenética, impactando procesos como la regulación transcripcional y la estructura de la cromatina. En términos de solubilidad, generalmente es soluble en agua y disolventes orgánicos, lo que facilita su uso en ensayos bioquímicos e investigación. Su estudio es importante para entender los mecanismos de regulación génica y las posibles implicaciones en enfermedades como el cáncer.

Fórmula: C₁₁H₁₅N₅O₃

InChI: InChI=1/C11H15N5O3/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(18)7(3-17)19-8/h4-8,17-18H,2-3H2,1H3,(H,12,13,14)/t6-,7+,8+/m0/s1

Clave InChI: InChIKey=DYSDOYRQWBDGQQ-XLPZGREQSA-N

SMILES: N(C)C1=C2C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)C3)=NC=N1

Sinónimos:

• 2'-Deoxy-N(6)-methyladenosine
• 2'-deoxy-N-methyladenosine
• 2′-Deoxy-N⁶-methyladenosine
• 6-(Methylamino)purine deoxyriboside
• Adenosine, 2'-deoxy-N-methyl-
• N(6)-Me-Dado
• N6-Methyl-2'-Deoxy-Adenosine
• N6-Methyl-2'-deoxyadenosine
• N⁶-Methyl-2′-deoxyadenosine
• N⁶-Methyldeoxyadenosine
• Nsc 66392
• N(6)-Methyl-2'-deoxyadenosine
• 2′-Deoxy-N6-methyladenosine
• N6-Me-dA
• (2R,3S,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol
• N6-Me-dAdo
• 6
• 2'-Deoxy-N
• (2R,3S,5R)-5-[6-(methylamino)purin-9-yl]-2-methylol-tetrahydrofuran-3-ol
• (2R,3S,5R)-2-(HydroxyMethyl)-5-(6-(MethylaMino)-9H-purin-9-yl)tetrahydrofuran-3-ol
• N6-Me-2'-deoxyadenosine
• -Methyladenosine
• -Me-dAdo
• 2'-Deoxy-N6-methyl-D-adenosine
• N6-Me-2'-dA
• N
• -Methyl-2'-deoxyadenosine

N6-Methyl-2'-deoxyadenosine, 99%

CAS: 2002-35-9

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Fórmula: C₁₁H₁₅N₅O₃

Pureza: 99%

Peso molecular: 265.27

Ref: 02-J64961

Adenosine, 2'-deoxy-N-methyl-

CAS: 2002-35-9

Fórmula: C₁₁H₁₅N₅O₃

Pureza: 95%

Forma y color: Solid

Peso molecular: 265.2685

Ref: IN-DA002CM4

N-6-Methyl-2-deoxyadenosine

CAS: 2002-35-9

N-6-Methyl-2-deoxyadenosine

Pureza: 95%

Peso molecular: 265.27g/mol

Ref: 54-OR1035917

2''-Deoxy-N6-methyladenosine

CAS: 2002-35-9

Fórmula: C₁₁H₁₅N₅O₃

Pureza: ≥ 99.0%

Forma y color: White powder

Peso molecular: 265.27

Ref: 7W-GN1250

N6-METHYL-2'-DEOXYADENOSINE

CAS: 2002-35-9

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 265.27301025390625

Ref: 10-F334242

N6-Methyldeoxyadenosine

CAS: 2002-35-9

N6-Methyldeoxyadenosine is an adenine nucleoside analogue exhibiting antimalarial activity against Plasmodium falciparum, with an IC₃₇ of 10 μM.

Fórmula: C₁₁H₁₅N₅O₃

Pureza: 99%

Forma y color: Solid

Peso molecular: 265.27

Ref: TM-TNU0419

2'-Deoxy-N-methyladenosine-d3

Producto controlado

CAS: 2002-35-9

Applications 2'-Deoxy-N-methyladenosine-d3 is the labelled form of 2'-Deoxy-N-methyladenosine (D242415). 2'-Deoxy-N-methyladenosine plays role in catalytic activity and may promote proper folding of A730 loop.
References Lafontaine, D. A., et al.: J. Mol. Biol., 323, 23-34 (2002)

Fórmula: C₁₁H₁₂D₃N₅O₃

Forma y color: Neat

Peso molecular: 268.29

Ref: TR-D242417

2'-Deoxy-N-methyladenosine

Producto controlado

CAS: 2002-35-9

Applications 2'-Deoxy-N-methyladenosine plays role in catalytic activity and may promote proper folding of A730 loop.
References Lafontaine, D. A., et al.: J. Mol. Biol., 323, 23-34 (2002)

Fórmula: C₁₁H₁₅N₅O₃

Forma y color: Neat

Peso molecular: 265.27

Ref: TR-D242415

2'-Deoxy-N6-methyladenosine

CAS: 2002-35-9

2'-Deoxy-N6-methyladenosine (2DMA) is a nucleoside that has been found to inhibit the phosphorylation of p2y receptors in rat kidney cells. 2DMA inhibits the production of collagen, which may have a matrix effect on cells. Studies have shown that 2DMA can be used as a sample preparation reagent for nuclear DNA. It has also been shown to be effective at inhibiting transcription and replication of human mitochondrial DNA.

Fórmula: C₁₁H₁₅N₅O₃

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 265.27 g/mol

Ref: 3D-ND06386