CAS 20153-98-4

Dihidrocloruro de dilazep

Descripción:

Dihidrocloruro de dilazep es un compuesto farmacéutico utilizado principalmente como vasodilatador y en el tratamiento de ciertas condiciones cardiovasculares. Pertenece a la clase de las benzodiazepinas y exhibe propiedades que pueden ayudar a mejorar el flujo sanguíneo al relajar los vasos sanguíneos. La sustancia se caracteriza por su forma de sal dihidrocloruro, que mejora su solubilidad en agua, haciéndola adecuada para diversas formulaciones, incluidas formas orales e inyectables. Dihidrocloruro de dilazep actúa inhibiendo la recaptación de ciertos neurotransmisores, influyendo así en el tono del músculo liso vascular. Su estructura química incluye un núcleo de benzodiazepina, lo que contribuye a sus efectos farmacológicos. El compuesto se administra típicamente bajo supervisión médica debido a posibles efectos secundarios, que pueden incluir mareos, dolor de cabeza o trastornos gastrointestinales. Al igual que con muchos medicamentos, es esencial considerar las contraindicaciones y las interacciones con otros fármacos. En general, Dihidrocloruro de dilazep desempeña un papel significativo en el manejo de condiciones de salud específicas relacionadas con la circulación sanguínea y la salud cardiovascular.

Fórmula: C₃₁H₄₄N₂O₁₀·2ClH

InChI: InChI=1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H

Clave InChI: InChIKey=VILIWRRWAWKXRW-UHFFFAOYSA-N

SMILES: C(OCCCN1CCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CCC1)(=O)C3=CC(OC)=C(OC)C(OC)=C3.Cl

Sinónimos:

• 1,4-Bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)perhydro-1,4-diazepine dihydrochloride
• 1,4-Bis{3-[(3,4,5-Trimethoxybenzoyl)Oxy]Propyl}-1,4-Diazepanediium Dichloride
• 1,4-Diazepane-1,4-Diyldipropane-3,1-Diyl Bis(3,4,5-Trimethoxybenzoate)
• 1H-1,4-Diazepine, benzoic acid deriv.
• 1H-1,4-Diazepine-1,4(5H)-dipropanol, tetrahydro-, bis(3,4,5-trimethoxybenzoate) (ester), dihydrochloride
• As 05
• Asta C
• Asta C 4898
• Benzoic acid, 3,4,5-trimethoxy-, (tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester, dihydrochloride
• Benzoic acid, 3,4,5-trimethoxy-, 1,1′-[(tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl] ester, hydrochloride (1:2)
• Benzoic acid, 3,4,5-trimethoxy-, diester with tetrahydro-1H-1,4-diazepine-1,4(5H)dipropanol, dihydrochloride
• Ccris 3782
• Comelian
• Cormelian
• Dilazep HCl
• Dilazep dihydrochloride
• K-285
• Labitan
• N,N'-(Bis-omega-hydroxypropyl)homopiperazine 3,4,5-trimethoxybenzoate dihydrochloride
• N,N'-Bis(3-(3,4,5-trimethoxybenzoyloxy)propyl)homopiperazine dihydrochloride
• N,N′-Bis[3′-(3′′,4′′,5′′-trimethoxybenzoyloxy)propyl]hexahydro-1,4-diazepine dihydrochloride

Dilazep dihydrochloride

CAS: 20153-98-4

Dilazep dihydrochloride

Pureza: ≥98%

Peso molecular: 677.61g/mol

Ref: 54-BUP15458

Dilazep dihydrochloride

CAS: 20153-98-4

Fórmula: C₃₁H₄₄N₂O₁₀·2HCl

Pureza: (HPLC) ≥ 98.0%

Forma y color: White to light yellow powder

Peso molecular: 677.61

Ref: 7W-GK0119

Dilazep dihydrochloride

CAS: 20153-98-4

Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.

Fórmula: C₃₁H₄₆Cl₂N₂O₁₀

Pureza: 98.39%

Forma y color: Solid

Peso molecular: 677.61

Ref: TM-T15130

Dilazep dihydrochloride

CAS: 20153-98-4

Dilazep dihydrochloride is a p2y receptor antagonist that prevents the activation of these receptors by extracellular nucleotides. It is used to treat angina and other cardiovascular diseases, as well as for the prevention of myocardial infarctions. Dilazep dihydrochloride has been shown to inhibit adenosine transport and uridine uptake in hl-60 cells. This agent also inhibits binding of dipyridamole and adenosine to their respective receptors, which may be due to its ability to block calcium influx through the p2y receptor and subsequent activation of adenylate cyclase. The increased intracellular concentration of ATP has been shown to have a number of physiological effects, including inhibition of platelet aggregation, stimulation of glucose transport, and enhancement of energy metabolism.

Fórmula: C₃₁H₄₄N₂O₁₀·2HCl

Pureza: Min. 95%

Peso molecular: 677.62 g/mol

Ref: 3D-VAA15398