CAS 2022-85-7

Flucitosina

Descripción:

Flucitosina, con el número CAS 2022-85-7, es un medicamento antifúngico que se utiliza principalmente para tratar infecciones fúngicas graves, particularmente aquellas causadas por especies de Candida y Cryptococcus. Es un análogo de pirimidina que interfiere con la síntesis de ácidos nucleicos al inhibir la timidilato sintasa, interrumpiendo en última instancia la síntesis de ADN y ARN fúngico. Flucitosina se administra típicamente en conjunto con otros agentes antifúngicos, como la anfotericina B, para mejorar su eficacia y reducir el riesgo de resistencia. La sustancia se absorbe bien cuando se toma por vía oral y se distribuye ampliamente por todo el cuerpo, incluido el sistema nervioso central, lo que la hace efectiva para tratar la meningitis criptocócica. Flucitosina generalmente es bien tolerado, pero puede causar efectos secundarios como supresión de la médula ósea y trastornos gastrointestinales. Su uso requiere un monitoreo cuidadoso de la función renal y de los conteos sanguíneos debido a la posible toxicidad. En general, Flucitosina es una herramienta valiosa en el arsenal antifúngico, particularmente para pacientes inmunocomprometidos.

Fórmula: C₄H₄FN₃O

InChI: InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)

Clave InChI: InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

SMILES: NC1=C(F)C=NC(=O)N1

Sinónimos:

• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
• 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
• 2-Hydroxy-4-Amino-5-Fluoropyrimidine
• 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
• 4-Amino-5-fluoro-2(1H)-pyrmidinone
• 4-Amino-5-fluoropyrimidin-2(1H)-one
• 4-Amino-5-fluoropyrimidin-2-ol
• 4-amino-1-fluoropyrimidin-2(1H)-one
• 5-Flucytosine
• 5-Fluoro Cytosine
• 5-Fluorocystosine
• 5-Fluorocytosin
• 5-Fluorocytosine
• 6-Amino-2-oxo-5-fluoropyrimidine
• 6-Amino-5-fluoro-2(1H)-pyrimidinone
• 6-amino-5-fluoropyrimidin-2(1H)-one
• Alcobon
• Ancobon
• Ancotil
• Ancotyl
• Cytosine, 5-fluoro-
• Flucitosina
• Flucylosine
• Flucytosin
• Flucytosine
• Fluocytosine
• Nsc 103805
• Ro 2-9915
• Toca FC
• 5-FC
• TIMTEC-BB SBB000061
• 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
• FLUCYSTINE
• fluorocytosine
• 4-amino-5-fluoro-2(1h)-pyrimidinon
• 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE

5-Fluorocytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 129.09

Ref: 3B-F0321

5-Fluorocytosine, 98+%

CAS: 2022-85-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₄H₄FN₃O

Pureza: 98+%

Forma y color: White, crystalline powder

Peso molecular: 129.09

Ref: 02-L16496

Flucytosine 2.0 mg/ml in Methanol

CAS: 2022-85-7

Forma y color: Single Solution

Ref: 61-AMP0355.00-07

Flucytosine

CAS: 2022-85-7

Forma y color: Neat

Ref: 61-FOR0355.00

FLUCYTOSINE RS

CAS: 2022-85-7

FLUCYTOSINE RS

Fórmula: C₄H₄FN₃O

Peso molecular: 129.0925

Ref: 41-ICRS0310

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

CAS: 2022-85-7

FLUCYTOSINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₄H₄FN₃O

Peso molecular: 129.0925

Ref: 41-Y0001262

FLUCYTOSINE CRS

CAS: 2022-85-7

FLUCYTOSINE CRS

Fórmula: C₄H₄FN₃O

Forma y color: Crystalline Powder. White. Powder.

Peso molecular: 129.0925

Ref: 41-F0175000

Flucytosine

CAS: 2022-85-7

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Fórmula: C₄H₄FN₃O

Forma y color: White Off-White Crystalline Powder

Peso molecular: 129.03384

Ref: 45-1272000

2(1H)-Pyrimidinone, 6-amino-5-fluoro-

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: 95%

Forma y color: Solid

Peso molecular: 129.0925

Ref: IN-DA002851

Flucytosine

CAS: 2022-85-7

Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.

Fórmula: C₄H₄FN₃O

Pureza: 98.76% - 99.28%

Forma y color: White Crystalline Solid Solid

Peso molecular: 129.09

Ref: TM-T0986

5-Fluorocytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 129.09

Ref: 7W-GA6771

Flucytosine

CAS: 2022-85-7

Flucytosine

Pureza: ≥98%

Peso molecular: 129.09g/mol

Ref: 54-BUP19221

5-Fluorocytosine

CAS: 2022-85-7

5-Fluorocytosine

Fórmula: C₄H₄FN₃O

Pureza: 97%

Forma y color: off white powder

Peso molecular: 129.09g/mol

Ref: 54-PC3735

Flucytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Peso molecular: 129.09

Ref: 4Z-F-422

5-Fluorocytosine

CAS: 2022-85-7

Pureza: 97%

Peso molecular: 129.09

Ref: FT-F14483

Flucytosine

CAS: 2022-85-7

Fórmula: C₄H₄FN₃O

Forma y color: Neat

Peso molecular: 129.09

Ref: 86-MM0355.00

Flucytosine

CAS: 2022-85-7

Forma y color: Neat

Ref: 04-C13700500

5-Fluoro Cytosine

Producto controlado

CAS: 2022-85-7

Applications 5-FC is a toxic antifungal/antimicrobial agent.
References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),

Fórmula: C₄H₄FN₃O

Forma y color: White To Off-White

Peso molecular: 129.09

Ref: TR-F589000

Cytosine-13C,15N2

CAS: 2022-85-7

Fórmula: CC₃H₅₁₅N₂NO

Forma y color: Off-White To Light Yellow

Peso molecular: 114.08

Ref: TR-C998952

5-Fluorocytosine

CAS: 2022-85-7

Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.

Fórmula: C₄H₄FN₃O

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 129.09 g/mol

Ref: 3D-FF02813