CAS 202409-33-4
:Etoricoxib
Descripción:
Etoricoxib es un inhibidor selectivo de la ciclooxigenasa-2 (COX-2), utilizado principalmente como un fármaco antiinflamatorio no esteroideo (AINE) para el tratamiento del dolor y la inflamación asociados con condiciones como la osteoartritis, la artritis reumatoide y el dolor agudo. Su fórmula química es C18H15N3O4S, y presenta un grupo sulfonamida, que contribuye a su actividad farmacológica. Etoricoxib exhibe una alta afinidad por COX-2, lo que lleva a una reducción en la producción de prostaglandinas, que son mediadores de la inflamación y el dolor. La sustancia se administra típicamente por vía oral y tiene una vida media relativamente larga, lo que permite una dosificación una vez al día. Los efectos secundarios comunes pueden incluir problemas gastrointestinales, riesgos cardiovasculares y efectos renales potenciales, similares a otros AINE. Etoricoxib está contraindicado en ciertas poblaciones, como aquellas con antecedentes de enfermedad cardiovascular o deterioro renal severo. En general, su acción dirigida sobre COX-2 lo convierte en una opción valiosa en el manejo del dolor, aunque es esencial considerar cuidadosamente su perfil de seguridad en el uso clínico.
Fórmula:C18H15ClN2O2S
InChI:InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3
Clave InChI:InChIKey=MNJVRJDLRVPLFE-UHFFFAOYSA-N
SMILES:ClC1=CC(=C(N=C1)C=2C=CC(C)=NC2)C3=CC=C(S(C)(=O)=O)C=C3
Sinónimos:- 2,3′-Bipyridine, 5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-
- 5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
- 5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)Phenyl]-2,3'-Bipyridine
- Algix
- Arcoxia
- Etobrix
- Etocox
- Etosaid
- Etoxib
- Etropain
- Kingcox
- Mk 0663
- Mk 663
- Nucoxia
- Tauxib
- Torcoxia
- Ver más sinónimos
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Encontrado 17 productos.
2,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS:Fórmula:C18H15ClN2O2SPureza:99%Forma y color:SolidPeso molecular:358.8419Ref: IN-DA002878
1g28,00€5g69,00€10g128,00€15g149,00€1kgA consultar25g155,00€50gA consultar75g566,00€100g528,00€500gA consultarEtoricoxib
CAS:Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties.Fórmula:C18H15ClN2O2SPureza:99.68%Forma y color:Off-White PowderPeso molecular:358.84Etoricoxib
CAS:Fórmula:C18H15ClN2O2SPureza:≥ 98.5% (dried basis)Forma y color:White to off-white or pale yellow crystalline powderPeso molecular:358.84Etoricoxib-13C-d3
CAS:Fórmula:C1713CH12D3ClN2O2SForma y color:White To Off-White SolidPeso molecular:362.85Etoricoxib
CAS:Fórmula:C18H15ClN2O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:358.84Etoricoxib-d6
CAS:Producto controlado<p>Applications Etoricoxib-d6 is the labelled analog of Etoricoxib (E934100), a specific inhibitor of COX-2 .<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Fórmula:C18H9D6ClN2O2SForma y color:NeatPeso molecular:364.885-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
CAS:Producto controlado<p>Etoricoxib is a cyclooxygenase-2 (COX-2) inhibitor, which is a type of nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the enzyme COX-2 that is involved in the production of certain hormones called prostaglandins. These hormones are involved in the inflammation (swelling and heat) associated with conditions such as arthritis. By blocking the action of the COX-2 enzyme, etoricoxib reduces the production of prostaglandins and thus, reduces the inflammation and pain. It has been observed that Etoricoxib shows a higher selectivity for COX-2 over COX-1 in diverse studies, with a COX-1/COX-2 IC50 ratio of 344 for in vitro assays, and it is involved in the modulation of NF-ΚB/COX-2/PGE2 signaling.</p>Fórmula:C18H15ClN2O2SPureza:Min. 95%Forma y color:PowderPeso molecular:358.84 g/molEtoricoxib - Bio-X ™
CAS:Producto controlado<p>Etoricoxib is a cyclooxygenase-2 (COX-2) inhibitor, which is a type of nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the enzyme COX-2 that is involved in the production of certain hormones called prostaglandins. These hormones are involved in the inflammation (swelling and heat) associated with conditions such as arthritis. By blocking the action of the COX-2 enzyme, Etoricoxib reduces the production of prostaglandins and thus, reduces the inflammation and pain. <br>Etoricoxib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Fórmula:C18H15ClN2O2SPureza:Min. 95%Forma y color:PowderPeso molecular:358.84 g/molEtoricoxib-13C,d3
CAS:Producto controladoFórmula:CC17D3H12ClN2O2SForma y color:NeatPeso molecular:362.853
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