CAS 20633-67-4

calicosina-7-O-beta-D-glucósido

Descripción:

calicosina-7-O-beta-D-glucósido es un glucósido flavonoide que se encuentra de forma natural, derivado principalmente de las raíces de las especies de Astragalus, en particular de Astragalus membranaceus. Este compuesto se caracteriza por su estructura, que consiste en una parte de calicosina unida a una molécula de glucosa a través de un enlace beta-glucosídico. Exhibe diversas actividades biológicas, incluyendo propiedades antioxidantes, antiinflamatorias y potenciales anticancerígenas, lo que lo convierte en un tema de interés en la investigación farmacológica. El compuesto es soluble en disolventes polares, y su estabilidad puede verse influenciada por factores como el pH y la temperatura. calicosina-7-O-beta-D-glucósido se estudia a menudo por sus posibles beneficios para la salud y aplicaciones terapéuticas, particularmente en la medicina tradicional. Su presencia en formulaciones herbales resalta su importancia en la química de productos naturales y la exploración de compuestos derivados de plantas para la salud y el bienestar. Al igual que muchos flavonoides, también puede contribuir a los perfiles de color y sabor de las plantas de las que se extrae.

Fórmula: C₂₂H₂₂O₁₀

InChI: InChI=1/C22H22O10/c1-29-15-5-2-10(6-14(15)24)13-9-30-16-7-11(3-4-12(16)18(13)25)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1

Sinónimos:

• 3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
• 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-
• Calycosin-O-Glucopyranoside
• Calycosin 7-O-Glucoside
• Calycosin 7-O-β-D-glucopyranoside

Calycosin 7-O-β-D-Glucopyranoside (3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen7-yl β-D-glucopyranoside)

CAS: 20633-67-4

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₂₂H₂₂O₁₀

Forma y color: Powder

Peso molecular: 446.1213

Ref: 45-1087483

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-

CAS: 20633-67-4

Fórmula: C₂₂H₂₂O₁₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 446.4041

Ref: IN-DA002IGF

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside

Pureza: ≥98%

Peso molecular: 446.4g/mol

Ref: 54-BUP07155

calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Fórmula: C₂₂H₂₂O₁₀

Peso molecular: 446.41

Ref: 7W-GY4388

calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-d-glucoside(CG) treatment can significantly reduce infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia–reperfusion rat model; inhibit the expression and activities of MMPs, and secure the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex; scavenge NO, inhibit the activities of MMP-2 and MMP-9, and attenuate cell death in the in vitro cultured brain microvascular endothelial cells under OGD condition; thus CG could protect BBB integrity in experimental cerebral ischemia–reperfusion injury via regulating NO/cav-1/MMPs pathway.

Fórmula: C₂₂H₂₂O₁₀

Pureza: 95%~99%

Forma y color: Powder

Peso molecular: 446.408

Ref: BP-BP0306

Calycosin 7-glucoside

CAS: 20633-67-4

Natural glycoside

Fórmula: C₂₂H₂₂O₁₀

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 446.41

Ref: 5G-82492

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside is a flavonoid glycoside, which is primarily derived from the root of Astragalus membranaceus, a plant widely used in traditional Chinese medicine. This compound is characterized by its antioxidative and anti-inflammatory activities, mediated through modulation of various signaling pathways in the body, such as the MAPK and NF-κB pathways. It plays a significant role in scavenging free radicals and inhibiting inflammatory mediators, thus contributing to cellular protection and reducing oxidative stress.

Fórmula: C₂₂H₂₂O₁₀

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 446.4 g/mol

Ref: 3D-MC44349

Calycosin-7-O-β-D-glucoside

CAS: 20633-67-4

Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity.

Fórmula: C₂₂H₂₂O₁₀

Pureza: 98% - 99.981%

Forma y color: Solid

Peso molecular: 446.4

Ref: TM-T3388

Calycosin 7-O-β-D-glucoside

Producto controlado

CAS: 20633-67-4

Applications Calycosin 7-O-β-D-glucoside is one of seven constituent in Guanjiekang (GJK) that is formed by five medicinal herbs that is used for the rheumatoid arthritis (RA).
References Wu, J., et al.: Mol., 21, 1732/1-1732/12 (2016)

Fórmula: C₂₂H₂₂O₁₀

Forma y color: Neat

Peso molecular: 446.40

Ref: TR-C148935