CAS 208538-73-2

Sodio de Micafungina

Descripción:

Sodio de Micafungina es un agente antifúngico que pertenece a la clase de las equinocandinas, utilizado principalmente en el tratamiento de infecciones fúngicas invasivas, particularmente aquellas causadas por especies de Candida y Aspergillus. Funciona inhibiendo la síntesis de β-(1,3)-D-glucano, un componente esencial de la pared celular fúngica, comprometiendo así la integridad estructural del hongo y llevando a la lisis celular. La micafungina se administra típicamente por vía intravenosa y se caracteriza por su actividad de amplio espectro contra varios patógenos fúngicos, lo que la convierte en una opción valiosa en entornos clínicos, especialmente para pacientes inmunocomprometidos. La sustancia es soluble en agua y exhibe estabilidad bajo condiciones fisiológicas. Su farmacocinética implica una vida media relativamente larga, lo que permite una dosificación una vez al día. Los efectos secundarios comunes pueden incluir reacciones relacionadas con la infusión, elevaciones de enzimas hepáticas y trastornos gastrointestinales. Debido a su mecanismo de acción y perfil de seguridad, la micafungina a menudo se prefiere en casos donde otras terapias antifúngicas pueden ser menos efectivas o contraindicadas.

InChI: InChI=1/C56H71N9O23S.Na/c1-4-5-6-17-86-32-14-11-28(12-15-32)39-21-33(63-87-39)27-7-9-29(10-8-27)49(75)58-34-20-38(70)52(78)62-54(80)45-46(72)25(2)23-65(45)56(82)43(37(69)22-41(57)71)60-53(79)44(48(74)47(73)30-13-16-36(68)40(18-30)88-89(83,84)85)61-51(77)35-19-31(67)24-64(35)55(81)42(26(3)66)59-50(34)76;/h7-16,18,21,25-26,31,34-35,37-38,42-48,52,66-70,72-74,78H,4-6,17,19-20,22-24H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)(H,83,84,85);/q;+1/p-1/t25-,26-,31+,34?,35-,37+,38+,42-,43-,44-,45-,46-,47+,48?,52-;/m1./s1

SMILES: CCCCCOc1ccc(cc1)c1cc(c2ccc(cc2)C(=O)NC2CC(C(N=C(C3C(C(C)CN3C(=O)C(C(CC(=N)O)O)N=C(C(C(C(c3ccc(c(c3)OS(=O)(=O)O)O)O)O)N=C(C3CC(CN3C(=O)C(C(C)O)N=C2O)O)O)O)O)O)O)O)no1.[Na]

Sinónimos:

• Fk 463
• 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((1R)-3-Amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((1R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-((4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoyl)amino)tetracosahydro-1H-dipyrrolo(2,1-c:2',1'-l)(1,4,7,10,13,16)hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sodium sulfate
• Fk463
• Unii-Is1Up79R56
• Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(5-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxy-3-(sulfooxy)phenyl)-L-threonine)-, monosodium salt

Micafungin Sodium

CAS: 208538-73-2

Fórmula: C56H70N9O23SNa

Pureza: ≥97% (HPLC)

Forma y color: white to beige powder

Peso molecular: 1292.26

Ref: 23-SML2268

Micafungin Sodium (INTERNATIONAL COLD SHIPMENT REQUIRED)

CAS: 208538-73-2

Antibiotics nesoi

Fórmula: C₅₆H₇₀N₉NaO₂₃S

Forma y color: White Powder

Peso molecular: 1291.4203

Ref: 45-1443384

Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-, sodium salt (1:1)

CAS: 208538-73-2

Fórmula: C₅₆H₇₀N₉NaO₂₃S

Pureza: 97%

Forma y color: Solid

Peso molecular: 1292.2563

Ref: IN-DA002JQV

Micafungin Sodium Salt

CAS: 208538-73-2

Fórmula: C₅₆H₇₀N₉O₂₃S·Na

Forma y color: White To Off-White Solid Solid

Peso molecular: 1269.29 22.99

Ref: 4Z-PM-127001

Micafungin (sodium)

CAS: 208538-73-2

Micafungin (sodium)

Pureza: 97%

Peso molecular: 1292.26g/mol

Ref: 54-OR1031626

Micafungin sodium

CAS: 208538-73-2

Fórmula: C₅₆H₇₁N₉O₂₃S·Na

Pureza: ≥ 98.0% (anhydrous)

Forma y color: White to off-white or beige powder

Peso molecular: 1292.28

Ref: 7W-GX5973

Micafungin sodium

CAS: 208538-73-2

Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri

Fórmula: C₅₆H₇₀N₉NaO₂₃S

Pureza: 98% - 99.41%

Forma y color: Solid

Peso molecular: 1292.26

Ref: TM-T1794

Micafungin Sodium

CAS: 208538-73-2

Stability Hygroscopic
Applications An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.
References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999);

Fórmula: C₅₆H₇₀N₉O₂₃S·Na

Forma y color: Off White

Peso molecular: 1292.26

Ref: TR-M342350

Micafungin sodium

CAS: 208538-73-2

Anti-fungal; glucan synthase inhibitor

Fórmula: C₅₆H₇₀N₉NaO₂₃S

Pureza: Min. 97 Area-%

Forma y color: White Powder

Peso molecular: 1,292.26 g/mol

Ref: 3D-FM34148

Micafungin-¹³C₆ Sodium

Producto controlado

CAS: 208538-73-2

Fórmula: C₅₀C₆H₇₀N₉NaO₂₃S

Forma y color: Neat

Peso molecular: 1298.22

Ref: TR-M442141

Micafungin-d11 Sodium

Producto controlado

CAS: 208538-73-2

Applications Micafungin-d11 Sodium is the isotope labelled analog of Micafungin Sodium (M342350); an echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall. Micafungin Sodium also represents a valuable treatment option for fungal infections.
References Chen, S.C. et al.: Drugs, 71, 11 (2011); Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2000); Tomishima, M. et al.: J. Antibiot., 52, 674 (1999)

Fórmula: C₅₆H₅₉D₁₁N₉NaO₂₃S

Forma y color: Neat

Peso molecular: 1303.33

Ref: TR-M342352

Micafungin sodium - Bio-X ™

CAS: 208538-73-2

Micafungin, as one of three echinocandina, has been proven to be a successful antifungal therapeutic in treating general Candida fungus infections. The treatment of immunocompromised patients is particularly important as Candida infections cause high mortality rates in patients in intensive care units, receiving chemotherapy, or stem cell transplants. This product acts as an anti-fungal by inhibiting the 1,3-beta-D-glucan synthase enzyme. As a result the production of 1,3-beta-D-glucan, which is crucial to the fungal cell wall, is hindered. Thus, the fungal cell wall loses integrity allowing for osmotic instability and cell lysis to occur.

Fórmula: C₅₆H₇₁N₉O₂₃S•Na

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,293.27 g/mol

Ref: 3D-BM164667