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CAS 2099014-23-8

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  • MJ04
    Targetmol
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    MJ04

    CAS:
    MJ04 is a selective inhibitor of Janus Kinase 3 (JAK3) with an IC50 of 2.03 nM. It hinders T cell differentiation and suppresses pro-inflammatory cytokines in macrophages induced by Lipopolysaccharides. In mice, MJ04 exhibits favorable pharmacokinetic properties and promotes hair growth in a DHT-induced alopecia model in athymic mice, without notable toxicity (LD50>2 g/kg).
    Fórmula:C20H16FN5
    Forma y color:Solid
    Peso molecular:345.37

    Ref: TM-T87974