CAS 2182-14-1

(-)-Vindolina

Descripción:

(-)-Vindolina es un alcaloide que se encuentra de forma natural, extraído principalmente de la planta Catharanthus roseus, comúnmente conocida como la vincapervinca de Madagascar. Se caracteriza por su estructura compleja, que incluye un marco tetracíclico y varios grupos funcionales, lo que contribuye a su actividad biológica. Este compuesto es conocido por su papel en la biosíntesis del fármaco anticancerígeno vincristina, lo que lo hace significativo en la química medicinal. (-)-Vindolina exhibe un centro quiral, lo que resulta en su actividad óptica específica, que es crucial para sus propiedades farmacológicas. La sustancia es típicamente un sólido cristalino blanco a blanco sucio y es soluble en disolventes orgánicos como el metanol y el etanol, pero menos soluble en agua. Su fórmula molecular refleja un grado de complejidad relativamente alto, y a menudo se estudia por sus posibles efectos terapéuticos, particularmente en oncología. Además, las interacciones de (-)-Vindolina con los mecanismos celulares y su capacidad para inhibir la división celular lo convierten en un tema de interés en la investigación del cáncer y el desarrollo de fármacos.

Fórmula: C₂₅H₃₂N₂O₆

InChI: InChI=1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-13H2,1-5H3/t19-,20+,21+,23+,24+,25-/m0/s1

Clave InChI: InChIKey=CXBGOBGJHGGWIE-ACSXSLCXSA-N

SMILES: C(C)[C@@]12[C@]3([C@@]4([C@]([C@](C(OC)=O)(O)[C@@H]1OC(C)=O)(N(C)C=5C4=CC=C(OC)C5)[H])CCN3CC=C2)[H]

Sinónimos:

• (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester
• 1H-Indolizino[8,1-cd]carbazole, aspidospermidine-3-carboxylic acid deriv.
• Aspidospermidine-3-Carboxylicacid,4-(Acetyloxy)-6,7-Didehydro-3-Hydroxy-16-Me
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
• Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-
• Bufexamacum
• Methyl (2Beta,3Beta,4Beta,5Alpha,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,3Beta,4Beta,5Alpha,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,3Beta,4Beta,5Xi,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• Methyl (2Beta,4Beta,5Alpha,12Beta,19Alpha)-4-(Acetyloxy)-3-Hydroxy-16-Methoxy-1-Methyl-6,7-Didehydroaspidospermidine-3-Carboxylate
• NSC 91994
• Thoxy-1-Methyl-,Methylester,(2-Beta,3-Beta,4-Beta,5-Alpha,12-Beta,19-Alpha)
• Vindolin
• Vindoline Tartrate
• Vindoline free base
• Vindoline, (-)-

Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-, methylester, (2b,3b,4b,5a,12R,19a)-

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Pureza: 95%

Forma y color: Solid

Peso molecular: 456.5314

Ref: IN-DA00I48E

Vindoline

CAS: 2182-14-1

Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.

Fórmula: C₂₅H₃₂N₂O₆

Pureza: 99.89%

Forma y color: White Or Offwhite Powder

Peso molecular: 456.53

Ref: TM-T2773

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Peso molecular: 456.54

Ref: 4Z-V-116001

Vindoline

CAS: 2182-14-1

Vindoline

Pureza: ≥98%

Peso molecular: 456.53g/mol

Ref: 54-BUP06409

Vindoline

CAS: 2182-14-1

Vindoline

Pureza: 98%

Peso molecular: 456.53g/mol

Ref: 54-OR1025615

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Pureza: >98.0%(HPLC)(qNMR)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 456.54

Ref: 3B-V0193

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Pureza: 95%~99%

Peso molecular: 456.539

Ref: BP-BP1443

Vindoline

CAS: 2182-14-1

Forma y color: Neat

Ref: 86-MM3359.01

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Pureza: (HPLC) ≥ 98.0%

Forma y color: White powder

Peso molecular: 456.53

Ref: 7W-GP8222

Vindoline

Producto controlado

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Forma y color: Neat

Peso molecular: 456.53

Ref: TR-V416500

Vindoline

Producto controlado

CAS: 2182-14-1

Vindoline is a monoterpenoid indole alkaloid that is found in plants of the genus Vinca. It has been used to prepare samples for thin-layer chromatography, and can be detected by sephadex g-100. The reaction mechanism of vindoline is thought to be similar to other indole alkaloids, such as tryptamine, where two molecules are combined through a covalent bond between the amine group and the carbonyl group. Vindoline has been shown to inhibit polymerase chain reactions and also has a number of biological properties that could be useful in tissue culture. This natural product structure has been shown to have steric interactions with enzymes, including tyrosinase, which is involved in plant metabolism. Vindoline may also be able to inhibit plant physiology by altering photosynthesis or respiration.

Fórmula: C₂₅H₃₂N₂O₆

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 456.53 g/mol

Ref: 3D-FV10830

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Peso molecular: 456.54

Ref: ST-EA-CP-V49003

Vindoline

CAS: 2182-14-1

Fórmula: C₂₅H₃₂N₂O₆

Forma y color: White To Off-White Solid

Peso molecular: 456.54

Ref: 4Z-V-040012