CAS 21967-41-9

Baicalina

Descripción:

Baicalina es un glucósido flavonoide derivado de las raíces de Scutellaria baicalensis, una planta comúnmente utilizada en la medicina tradicional china. Su estructura química consiste en un esqueleto de flavona con un moiety de ácido glucurónico, que contribuye a su solubilidad y bioactividad. Baicalina es conocido por sus diversas propiedades farmacológicas, incluyendo efectos antiinflamatorios, antioxidantes y neuroprotectores. Se ha estudiado por sus posibles aplicaciones terapéuticas en condiciones como la ansiedad, la depresión y las enfermedades neurodegenerativas. El compuesto presenta un perfil de toxicidad relativamente bajo, lo que lo convierte en un candidato para investigaciones adicionales en química medicinal. Baicalina se caracteriza típicamente por su color amarillento y es soluble en agua y alcohol, pero menos en disolventes no polares. Su mecanismo de acción implica la modulación de diversas vías de señalización, incluidas las relacionadas con el estrés oxidativo y la inflamación. En general, Baicalina representa un área de interés significativa tanto en la química de productos naturales como en la farmacología debido a sus diversas actividades biológicas y posibles beneficios para la salud.

Fórmula: C₂₁H₁₈O₁₁

InChI: InChI=1/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)

Clave InChI: InChIKey=IKIIZLYTISPENI-ZFORQUDYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=CC=C3)=CC(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=C1O

Sinónimos:

• 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 5,6-Dihydroxy-4-oxygen-2-phenyl-4H-1-benzopyran-7-beta-D-glucopyranose acid
• 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid
• 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl hexopyranosiduronic acid
• Baicalein 7-O-glucuronide
• Baicalein 7-O-β-<span class="text-smallcaps">D</span>-glucuronide
• Baicalein 7-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• Baicalin
• 5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
• β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl
• Baicalein 7-O-β-D-glucuronide
• BAICALIN 7-B-D-GLUCOPYRANOSIDURONATE HYDRATE
• BAICALIN(P)
• BAICALIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
• Bassora
• Baicalin Injection
• BAICALIN HYDRATE
• Baicailin
• Radix
• BAICALIN, 98+% BY HPLC
• BAICALEIN 7-BETA-D-GLUCOPYRANOSIDURONATE HYDRATE
• ASTRAGALIN(KAEMPFEROL-3-O-GLUCOSIDE)(P)
• BAICALINB-D-GLUCOPYRANOSIDURONIC ACID, 5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-1-BENZOPYRAN-7-YL,
• BAICALIN hplc
• 7-GLUCURONICACID-5,6-DIHYDROXYFLAVONE
• BAICALIN WITH HPLC
• 5,6-Dihydroxyflavon-7-yl β-D-glucopyranosiduronic acid

Baicalin

CAS: 21967-41-9

Fórmula: C₂₁H₁₈O₁₁

Pureza: >90.0%(T)

Forma y color: White to Yellow powder to crystal

Peso molecular: 446.36

Ref: 3B-B2835

Baicalin

CAS: 21967-41-9

Baicalin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₁H₁₈O₁₁

Pureza: (HPLC) ≥99%

Forma y color: Powder

Peso molecular: 446.36

Ref: 11-1280S

BAICALIN CRS

CAS: 21967-41-9

BAICALIN CRS

Fórmula: C₂₁H₁₈O₁₁

Forma y color: Powder.

Peso molecular: 446.361

Ref: 41-Y0001273

Baicalein 7-O-Glucuronide

CAS: 21967-41-9

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₂₁H₁₈O₁₁

Forma y color: Yellow Powder

Peso molecular: 446.36

Ref: 45-1048368

Baicalin

CAS: 21967-41-9

Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV

Fórmula: C₂₁H₁₈O₁₁

Pureza: 90.08% - 99.32%

Forma y color: Yellow Powder

Peso molecular: 446.36

Ref: TM-T2775

(2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS: 21967-41-9

Fórmula: C₂₁H₁₈O₁₁

Pureza: 90%

Forma y color: Solid

Peso molecular: 446.3610

Ref: IN-DA00I49P

Baicalin 7-b-D-glucuronide

CAS: 21967-41-9

Fórmula: C₂₁H₁₈O₁₁

Pureza: ≥ 95.0%

Forma y color: White, off-white or yellow powder

Peso molecular: 446.36

Ref: 7W-GC0614

Baicalin

CAS: 21967-41-9

Baicalin

Pureza: 90%

Peso molecular: 446.36g/mol

Ref: 54-OR1028641

Baicalin

CAS: 21967-41-9

Baicalin

Pureza: ≥90%

Peso molecular: 446.36g/mol

Ref: 54-BUP14961

Baicalin

CAS: 21967-41-9

Baicalin is a flavonoid and a major component of a herbal medicine, Sho-saiko-to, which is commonly used for treatment of chronic hepatitis in Japan and China. baicalin acts as anti-oxidants, also causes cytotoxic effect,and induces caspase-3 activation and apoptosis via mitochondrial pathway.

Fórmula: C₂₁H₁₈O₁₁

Pureza: 95%~99%

Forma y color: Yellow powder

Peso molecular: 446.364

Ref: BP-BP0233

Baicalin

CAS: 21967-41-9

Fórmula: C₂₁H₁₈O₁₁

Forma y color: Neat

Peso molecular: 446.36

Ref: 04-C10418100

Baicalin RS

CAS: 21967-41-9

Forma y color: Pale Yellow To Yellow

Ref: 2K-1111000021

Baicalin

CAS: 21967-41-9

Natural glycoside

Fórmula: C₂₁H₁₈O₁₁

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 446.37

Ref: 5G-89322

Baicalin

Producto controlado

CAS: 21967-41-9

Stability Hygroscopic
Applications Baicalin, Baicalin is the glucuronide of Baicalein (B115250). Baicalin is a known prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells,[3] and affects the GABA receptors.
References Tarrago, T., et al.: Bioorg. Med. Chem, 16 (15), 7516 (2008); Takahashi, H., et al.: Biochim Biophys Acta, 1813 (8), 1465 (2011);

Fórmula: C₂₁H₁₈O₁₁

Forma y color: Neat

Peso molecular: 446.36

Ref: TR-B115255

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl ?-D-Glucopyranosiduronic Acid

CAS: 21967-41-9

Fórmula: C₂₁H₁₈O₁₁

Pureza: 98.0%

Peso molecular: 446.364

Ref: 10-F547433

(2S,3S,4S,5R,6S)-6-[(4,6-dihydroxy-5-oxo-2-phenyl-5H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS: 21967-41-9

Pureza: 95%

Peso molecular: 446.3640137

Ref: 10-F808019

Baicalin 7-b-D-glucuronide

CAS: 21967-41-9

Baicalin 7-b-D-glucuronide is a flavonoid metabolite, which is primarily derived from the root of the plant *Scutellaria baicalensis*, commonly known as Chinese skullcap. This compound occurs as part of the extensive array of flavonoids in traditional medicinal plants used in various ethnic medicine systems.

Fórmula: C₂₁H₁₈O₁₁

Pureza: Min. 95 Area-%

Forma y color: White Powder

Peso molecular: 446.36 g/mol

Ref: 3D-MB08110