CAS 2231744-29-7

MT-802

CAS: 2231744-29-7

MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL).

Fórmula: C₄₁H₄₁N₉O₈

Pureza: 95.93% - 97%

Forma y color: Solid

Peso molecular: 787.82

Ref: TM-T16157

2-(2-(2-(4-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide

CAS: 2231744-29-7

Fórmula: C₄₁H₄₁N₉O₈

Pureza: 95%

Forma y color: Solid

Peso molecular: 787.8197

Ref: IN-DA01MVL4

2-(2-(2-(4-(4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Piperidin-1-Yl)Ethoxy)Ethoxy)-N-(2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-5-Yl)Acetamide

CAS: 2231744-29-7

2-(2-(2-(4-(4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-1-Yl)Piperidin-1-Yl)Ethoxy)Ethoxy)-N-(2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-5-Yl)Acetamide

Pureza: 99%

Peso molecular: 787.82g/mol

Ref: 54-OR1024051

MT-802

CAS: 2231744-29-7

MT-802

Pureza: ≥95%

Peso molecular: 787.82g/mol

Ref: 54-BUP12854

MT-802

CAS: 2231744-29-7

MT-802 is a small molecule that inhibits the ubiquitin-proteasome system. It has been shown to inhibit tumor xenografts and chronic lymphocytic leukemia in animal models. MT-802 molecule has also shown efficacy in treating autoimmune diseases, such as lupus. The drug works as a covalent inhibitor of polyubiquitin, which is involved in the process of protein degradation by proteasomes. MT-802 binds to polyubiquitin and irreversibly inhibits its function, leading to increased degradation of proteins and inhibition of tumor growth.

Fórmula: C₄₁H₄₁N₉O₈

Pureza: Min. 95%

Peso molecular: 787.8 g/mol

Ref: 3D-GPD74429