CAS 22457-89-2

S-benzoiltiamina O-monofosfato

Descripción:

S-benzoiltiamina O-monofosfato, con el número CAS 22457-89-2, es un derivado de la tiamina (vitamina B1) que ha sido modificado para incluir un grupo bencilo y un grupo fosfato. Este compuesto se caracteriza por su papel como un análogo de la tiamina, que puede influir en las reacciones enzimáticas que involucran enzimas dependientes de la tiamina. Típicamente exhibe propiedades como solubilidad en disolventes polares, lo cual es común en los ésteres fosfatados, y puede tener una estabilidad variable dependiendo de las condiciones de pH y temperatura. La presencia del grupo bencilo puede mejorar su lipofilia en comparación con la tiamina, afectando potencialmente su biodisponibilidad e interacción con sistemas biológicos. S-benzoiltiamina O-monofosfato se estudia a menudo por sus propiedades bioquímicas y aplicaciones potenciales en nutrición y farmacología, particularmente en relación con sus efectos en las vías metabólicas y su papel en la producción de energía celular. Al igual que muchos derivados de la tiamina, también puede exhibir propiedades antioxidantes, contribuyendo a su relevancia en contextos de salud y enfermedad.

Fórmula: C₁₉H₂₃N₄O₆PS

InChI: InChI=1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)

Clave InChI: InChIKey=BTNNPSLJPBRMLZ-UHFFFAOYSA-N

SMILES: C(N(C(=C(SC(=O)C1=CC=CC=C1)CCOP(=O)(O)O)C)C=O)C=2C(N)=NC(C)=NC2

Sinónimos:

• 8088Cb
• Benfothiamine
• Benfotiamine
• Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester
• Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester
• Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester)
• Benzoylthiamine O-monophosphate
• Benzoylthiamine monophosphate
• Berdi
• Betivina
• Bietamine
• Biotamin
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate)
• Milgamma
• N-((4-Amino-2-Methyl-5-Pyrimidinyl)Methyl)-N-(4-Hydroxy-2-Mercapto-1-Methyl-1-Butenyl)Formamide-S-Benzoate Dihydrogen Phosphate
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate
• Neurostop
• Nitanevril
• S-Benzoylthiamine monophosphate
• S-[2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-5-(phosphonooxy)pent-2-en-3-yl] benzenecarbothioate
• S-{(1E)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-1-[2-(phosphonooxy)ethyl]prop-1-en-1-yl} benzenecarbothioate
• S-{(1Z)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-1-[2-(phosphonooxy)ethyl]prop-1-en-1-yl} benzenecarbothioate
• Tabiomyl

Benfotiamine

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 466.45

Ref: 3B-B4711

{[(3E)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-[(E)-benzoylsulfanyl]pent-3-en-1-yl]oxy}phosphonic acid

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: 97%

Forma y color: Solid

Peso molecular: 466.4479

Ref: IN-DA007OGT

Benfotiamine

CAS: 22457-89-2

Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: 99.2% - 99.91%

Forma y color: Shinning Black Powder

Peso molecular: 466.45

Ref: TM-T1129

Benfotiamine

CAS: 22457-89-2

Benfotiamine

Pureza: ≥98%

Peso molecular: 466.45g/mol

Ref: 54-BUP16881

Benfotamine

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: 98.0 - 102.0 % (dried basis)

Forma y color: White to off-white powder

Peso molecular: 466.45

Ref: 7W-GP2430

Benfotiamine

CAS: 22457-89-2

Benfotiamine

Pureza: 99%

Peso molecular: 466.45g/mol

Ref: 54-OR1030007

Benfotiamine

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Forma y color: White To Off-White Solid

Peso molecular: 466.45

Ref: 4Z-B-208001

Benfotiamine

Producto controlado

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Forma y color: Neat

Peso molecular: 466.45

Ref: TR-B136000

Benfotiamine

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Peso molecular: 466.45

Ref: ST-EA-CP-B44000

Benfotiamine-Amide

Producto controlado

CAS: 22457-89-2

Stability Hygroscopic
Applications Benfotiamine-Amide is an analog of Benfotiamine, which is a Vitamin B1 analog. Synthetic S-acyl derivative of Thiamine (T344185).
References Stracke, H., et al.: Exper. Clin. Endocrinol., Diabetes, 116, 600 (2008), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010),

Fórmula: C₂₆H₂₇N₄O₇PS

Forma y color: Neat

Peso molecular: 570.55

Ref: TR-B136003

Benfotiamine

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Ref: TR-TRC-B136000

Benfotiamine

CAS: 22457-89-2

Benfotiamine is a thiamine derivative that is structurally similar to thiamine. It has been shown to have pharmacological effects in experimental models of diabetic complications and may be a potential therapeutic agent for the treatment of these conditions. Benfotiamine binds to the response element on the nuclear DNA, which leads to an increase in calcium pantothenate, a cofactor necessary for energy metabolism in mitochondria. The enzyme activities of benfotiamine are also modulated by calcium and magnesium ions. Benfotiamine can be used as an analytical method for nonsteroidal anti-inflammatory drugs (NSAIDs) by measuring the levels of benzoquinone imines and fluoroquinolones in urine.

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 466.45 g/mol

Ref: 3D-FB18169

S-(2-(N-((4-Amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl)benzothioa

CAS: 22457-89-2

Fórmula: C₁₉H₂₃N₄O₆PS

Pureza: 97%

Forma y color: Solid, White to almost white powder

Peso molecular: 466.45

Ref: 10-F093454