CAS 2246380-69-6

MAC glucuronide phenol-linked SN-38

CAS: 2246380-69-6

pH-sensitive lactone drug linker, inhibits DNA topoisomerase I, cytotoxic in L540cy/Ramos cells, IC50: 113/67 ng/mL.

Fórmula: C₅₀H₅₄N₆O₂₀S

Pureza: 98%

Forma y color: Solid

Peso molecular: 1091.06

Ref: TM-T18538

Mac glucuronide phenol-linked sn-38

CAS: 2246380-69-6

Mac glucuronide phenol-linked SN-38 is a chemically engineered prodrug derived from irinotecan. This compound serves as a targeted therapeutic agent, designed to enhance the delivery and activation of SN-38, an active metabolite, at tumor sites. The source of this product arises from the selective conjugation of SN-38 with a glucuronide moiety, linked through a phenolic connector, enabling preferential release in the tumor microenvironment.

Fórmula: C₅₀H₅₄N₆O₂₀S

Pureza: Min. 95%

Peso molecular: 1,091.06 g/mol

Ref: 3D-WPD38069