CAS 22465-48-1

Acetatocobalamina

Descripción:

Acetatocobalamina, también conocido como acetato de vitamina B12, es un derivado de la cobalamina, que es esencial para diversas funciones biológicas en el cuerpo humano. Se caracteriza por su estructura de anillo corrin que contiene cobalto, que es central para su actividad como cofactor en reacciones enzimáticas, particularmente en la síntesis de ADN y la formación de glóbulos rojos. Acetatocobalamina es típicamente un polvo cristalino rojo, que refleja el color característico de los compuestos de vitamina B12. Es soluble en agua y exhibe estabilidad en condiciones normales, aunque puede ser sensible a la luz y al calor. Este compuesto juega un papel crucial en el metabolismo de ácidos grasos y aminoácidos, y su deficiencia puede llevar a problemas de salud graves, incluyendo anemia y trastornos neurológicos. Acetatocobalamina se utiliza a menudo en suplementos dietéticos y alimentos fortificados para prevenir o tratar la deficiencia de vitamina B12. Su biodisponibilidad y efectividad en el cuerpo lo convierten en un compuesto importante en la ciencia nutricional y la medicina.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

InChI: InChI=1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+3/p-3

Clave InChI: InChIKey=KPFAAKYTRSSOQN-UHFFFAOYSA-K

SMILES: [O-](C(C)=O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Sinónimos:

• Acetatocobalamin
• Co(Acetato-kappaO)cobinamide dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobalamin, acetato-
• Cobalamin, acetato- (6CI)
• Cobinamide, Co(acetato-kappaO)-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobinamide, Co-(acetato-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole, inner salt
• Depo-gamma
• Fresmin S
• Hydroxocobalamine acetate
• Hydroxycobalamine acetate
• Novidroxin
• Twelvmin
• Unii-S535M27N3Q
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole, inner salt

Hydroxocobalamin Acetate

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: >90.0%(HPLC)

Forma y color: Orange to Brown to Dark red powder to crystal

Peso molecular: 1,388.41

Ref: 3B-H1542

Hydroxocobalamin Acetate

CAS: 22465-48-1

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Forma y color: Dark Red Powder

Peso molecular: 1387.57763

Ref: 45-1324308

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate treats B12 deficiency and cyanide poisoning; FDA-approved with few side effects.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 96.73% - 99.86%

Forma y color: Solid

Peso molecular: 1388.39

Ref: TM-T13730

Hydroxocobalamin acetate

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 96.0 - 102.0 %

Forma y color: Dark red crystalline powder or crystals

Peso molecular: 1388.39

Ref: 7W-GE5819

Hydroxycobalamine Acetate

CAS: 22465-48-1

Hydroxycobalamine Acetate

Pureza: 98%

Peso molecular: 1,388.39g/mol

Ref: 54-OR1013546

Hydroxocobalamin Acetate (Vitamin B12 Analog)

CAS: 22465-48-1

Fórmula: C₆₄H₉₂CoN₁₃O₁₆P

Forma y color: Dark Red Solid

Peso molecular: 1389.42

Ref: 4Z-V-035001

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate

Pureza: ≥95%

Peso molecular: 1388.39g/mol

Ref: 54-BUP14167

Hydroxocobalamin Acetate

CAS: 22465-48-1

Fórmula: C₆₂H₈₉CoN₁₃O₁₅PC₂H₄O₂

Peso molecular: 1346.38 : 60.05

Ref: ST-EA-CP-H13001

Hydroxocobalamin Acetate

Producto controlado

CAS: 22465-48-1

Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Forma y color: Dark Red

Peso molecular: 1388.39

Ref: TR-H826800

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate is a water-soluble form of hydroxocobalamin, a vitamin B12 prodrug. It is an insoluble polymer that dissolves slowly in an acidic environment. Hydroxocobalamin acetate has been shown to inhibit the growth of human carcinoma cells in culture and can be used as a test compound for anticancer drugs. Hydroxocobalamin acetate is also used as a mouth rinse agent to prevent or treat dental cavities. In addition, it can be used to relieve the symptoms of gastroesophageal reflux disease (GERD) by reducing the acidity of gastric contents. This drug has been shown to stimulate vasoactive intestinal polypeptide release from enterochromaffin cells and can be used for the treatment of irritable bowel syndrome (IBS). Hydroxocobalamin acetate is poorly soluble in neutral pH environments and should not be given orally.

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: Min. 90 Area-%

Forma y color: Red Powder

Peso molecular: 1,388.39 g/mol

Ref: 3D-FH23894

Cobinamide, Co-(acetato-kO)-, dihydrogen phosphate (ester), innersalt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)

CAS: 22465-48-1

Fórmula: C₆₄H₉₁CoN₁₃O₁₆P

Pureza: 98%

Forma y color: Solid

Peso molecular: 1388.3918

Ref: IN-DA00I4FP